| Sega Mega Drive cart. |  Comix Zone Model G-4132 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Crack Down Model 1111-50 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. |  Crack Down Model G-4024 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Crying - Aseimei Sensou Model G-4087 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Cyber Police ESWAT Model G-4029 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | CyberBall - Football in the 21st Century Model G-4027 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Daffy Duck in Hollywood Model 1094-50 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Dai Senpuu Model G-4034 P | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Daimakaimura Model G-4013 P | 1989 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Darwin 4081 Model G-4033 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | David Robinson Basketball | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. |  David Robinson's Supreme Court | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | DecapAttack Model 1027-50 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Demolition Man Model T-81486-50 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Disney's Aladdin | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Disney's TaleSpin | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Disney's Toy Story Model 1193-50 | 1996 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | DJ Boy | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Donald in Maui Mallard Model 1192-50 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Doraemon - Yume Dorobou to 7-nin no Gozans Model G-4094 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Double Clutch | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Dr. Robotnik's Mean Bean Machine Model 1706-50 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Dragon Slayer - Eiyuu Densetsu II Model G-5544 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Dragon Slayer - Eiyuu Densetsu Model G-5536 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Dynamite Duke Model G-4038 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Dynamite Headdy Model 1543-50 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Dynamite Headdy Model G-4117 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Ecco - The Tides of Time Model 1553-50 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Ecco Jr. Model FECC0035MC | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Ecco the Dolphin II Model G-4123 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Ecco the Dolphin Asian Version | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Ecco the Dolphin Model 1042-50 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Ecco the Dolphin Model G-4106 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Escape from Mars Starring Taz | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | ESWAT - City Under Siege | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Eternal Champions Model 1145-50 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Eternal Champions Model 1145 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Eternal Champions Model G-4114 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Ex-Ranza Model G-4097 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Fantasia Model 1021-50 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
