| Sega Saturn CD |  Shining Wisdom | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega SG-1000 game | Shinnyushain Tooru Kun Model G-1041 | 1985 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Play cart. | Shinobi III - Return of the Ninja Master Model 09 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. |  Shinobi III - Return of the Ninja Master Model 1136-50 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Shinobi X | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega-Tech cart. | Shinobi Model 08 | 1989 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Shinobi Model 317-0049 | 1987 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mark III cart. | Shinobi Model G-1352 | 1988 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Master System cart. | Shinobi Model G-1353 P | 1988 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Master System cart. | Shinobi Model MK-7009-50 P | 1988 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Shinseiki Evangelion | 1996 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Shinseiki Evangelion - 2nd Impression | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Shinsetsu Yumemi Yakata - Tobira no Oku ni Darekaga... Model GS-9005 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Master System cart. | Shooting Gallery Model MK-5072-50 | 1987 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Shooting Master | 1985 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Shooting Zone | 1987 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Shoujo Kakumei Utena Itsuka Kakumei Sareru Monogatari | 1998 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shura no Mon Model G-4073 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Side Pocket Model 670-2893-50 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega-CD | Silpheed Model 4423 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega CD | Silpheed Model T-4423 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Redemption mechanical game | Silver Queen | 198? | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sim City 2000 Model GS-9027 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sim City 2000 Model MK81580-50 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega-CD | SimEarth Model G-6008 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Sindbad Mystery | 1983 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega SG-1000 game | Sindbad Mystery Model G-1012 | 1983 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega-CD | Sing! Teddyboy Blues | 19?? | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega CD |  Sister Sonic | 199? | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Ski Champ | 1998 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Redemption mechanical game | Skill Diga | 1968 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega ST-V cart. | Sky Challenger | 2000 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Pinball | Sky Lover | 1977 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Sky Target | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sky Target | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sky Target | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sky Target | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Slap Shooter | 1986 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Master System cart. | Slap Shot Model 7035 | 1989 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega NAOMI cart. | Slash Out Model 840-0041C | 2000 | SEGA Enterprises, Ltd. Tokyo, Japan |
