| Sega Mega Drive cart. |  Samurai Spirits Model G-4127 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Coin-op Misc. game | Sand Buggy | 1972 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega ST-V cart. | Sando-R - Puzzle & Action Model 610-0373-11 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Sangokushi Retsuden - Ransei no Eiyuutachi Model G-5504 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Sanrin San-Chan - Tricycle-San | 1984 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Pico game | Sanrio Carnival Tanoshii Card Dukuri Model HPC-6031 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Pico game | Sanrio Puroland de Dance Carnival - Minna de Oryouri Osaihou Model HPC-6026 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Pinball | Sapporo | 1972 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mark III card | Satellite 7 Model C-506 | 1985 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Saturn Bomberman | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Saturn Bomberman Model 81070 | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Coin-op Misc. game | Saurus Wars | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Scholastic's The Magic School Bus | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Pico game | Scholastic's The Magic School Bus Model 49038-00 | 199? | SEGA Enterprises, Ltd. Tokyo, Japan |
| Redemption mechanical game | School Kids | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Scorcher | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Scorcher Model 81214 | 1996 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega System 24 disk | Scramble Spirits | 1988 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Master System cart. | Scramble Spirits Model 7031 P | 1989 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Scud - The Disposable Assassin Model 14003 | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Scud Race | 1996 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Scud Race Plus | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | SDI - Strategic Defense Initiative Model 317-0027 | 1987 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mark III cart. | SDI Model G-1338 P | 1987 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Gun game | Sea Devil | 1972 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Secret Base | 1978 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Master System cart. |  Secret Command Model MK-5081-50 | 1987 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Secret War | 1978 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game |  Seeker Head | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Seesaw Jump Cocktail model | 1978 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Seesaw Jump Upright model | 1978 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sega Ages Vol.1 Model MK81604-50 | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sega Ages: Fushigi no Oshiro Daibouken + Guruzia Ou no Hihou Model GS-9179 P | 1998 | SEGA Enterprises, Ltd. Tokyo, Japan |
| PC/MS-Windows CD | Sega Archives from USA Vol. 1 | 2000 | SEGA Enterprises, Ltd. Tokyo, Japan |
| PC/MS-Windows CD | Sega Archives from USA Vol. 2 | 2000 | SEGA Enterprises, Ltd. Tokyo, Japan |
| PC/MS-Windows CD | Sega Archives from USA Vol. 3 | 2000 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Sega Bass Fishing Deluxe | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Dreamcast GD | Sega Bass Fishing Model MK-51006-05 | 1999 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Slot Machine | Sega Bell Type A | 195? | SEGA Enterprises, Ltd. Tokyo, Japan |
| Slot Machine | Sega Bell Type B | 195? | SEGA Enterprises, Ltd. Tokyo, Japan |
