| Slot Machine |  Star of India | 2005 | WMS Gaming, Inc. Chicago, IL, USA |
| Sony PSP UMD | Star Soldier Model ULJM-05026 | 2005 | Hudson Soft. Hudson Group Japan |
| Sky Gamestar game | Star Trek The Next Generation - STRANDED | 2005 | Sky Games |
| Apple Macintosh CD | Star Wars - Battlefront P | 2005 | Aspyr |
| PC/MS-Windows CD | Star Wars - Battlefront II | 2005 | LucasArts Ent. Co. |
| Sony PSP UMD | Star Wars - Battlefront II Model ULES-00183 | 2005 | LucasArts Ent. Co. |
| Sony PSP UMD | Star Wars - Battlefront II Model ULUS-10053 | 2005 | LucasArts Ent. Co. |
| Nintendo GBA cart. | Star Wars - Episode III - Revenge of the Sith Model AGB-BE3E-USA | 2005 | Ubisoft Ent. Montreuil sous Bois, France |
| Nintendo GBA cart. | Star Wars - Episode III - Revenge of the Sith Model AGB-BE3P | 2005 | Ubisoft Ent. Montreuil sous Bois, France |
| PC/MS-Windows CD | Star Wars - Republic Commando | 2005 | LucasArts Ent. Co. |
| Dedicated Console | Star Wars - Revenge of the Sith | 2005 | Jakks Pacific, Inc. |
| Nintendo DS cart. | Star Wars Episode III - Revenge of the Sith Model NTR-ASTE-USA | 2005 | Ubisoft Ent. Montreuil sous Bois, France |
| PC/MS-Windows CD | Star Wars Galaxies - Rage of the Wookiees | 2005 | LucasArts Ent. Co. |
| PC/MS-Windows CD | Star Wars Galaxies - Trials of Obi-Wan | 2005 | LucasArts Ent. Co. |
| PC/MS-Windows CD | Star Wolves | 2005 | 1C Co. Russia |
| PC/MS-Windows CD | Starship Troopers | 2005 | Empire Interactive Europe, Ltd. |
| Sony PlayStation 2 disc | Steel Dragon EX Model SLES-52482 | 2005 | Midas Int. Ent. |
| Nintendo GBA cart. | Steel Empire Model AGB-BKTP | 2005 | Zoo Digital Publishing |
| PC/MS-Windows CD | Still Life | 2005 | Microïds |
| Redemption mechanical game | Stock Car Challenge | 2005 | Bay Tek Games, Inc. Pulaski, WI, USA |
| Mattel Intellivision cart. | Stonix Model 9112 | 2005 | IntelligentVision |
| Medal video game | Storm of Desert | 2005 | Unknown Korea |
| Sinclair ZX Spectrum cass. | Stranded Hb | 2005 | Cronosoft |
| Nintendo GBA cart. | Strawberry Shortcake - Summertime Adventure - Special Edition Model AGB-BQWE-USA | 2005 | Majesco Ent. Co. |
| Pachislot | Street Fighter II - The World Warrior | 2005 | Aristocrat Technologies Co., Ltd. Tokyo, Japan |
| Nintendo GBA cart. | Street Racing Syndicate Model AGB-BCZE-USA | 2005 | DSI Games |
| Nintendo GBA cart. | Street Racing Syndicate Model AGB-BCZP | 2005 | Zoo Digital Publishing |
| Nintendo GameCube disc | Strike Force Bowling | 2005 | Crave Ent., Inc. |
| PC/MS-Windows CD | Stronghold 2 | 2005 | 2K Games, Inc. New York, NY, USA |
| PC/MS-Windows CD | Stubbs the Zombie in Rebel Without a Pulse | 2005 | Aspyr |
| Apple Macintosh CD | Stubbs the Zombie in Rebel Without a Pulse | 2005 | Aspyr |
| PC/MS-Windows CD | Sudeki | 2005 | Zoo Digital Publishing |
| Nintendo GBA cart. | Sugar Sugar Rune - Heart Ga Ippai! Moegi Gakuen Model AGB-B4LJ-JPN | 2005 | Bandai Co., Ltd. Japan |
| Medal video game | Summer Time | 2005 | Andamiro Co., Ltd. |
| Nintendo GBA cart. | Summon Night - Craft Sword Monogatari - Hajimari no Ishi Model AGB-B3CJ-JPN | 2005 | Banpresto Japan |
| Slot Machine | Sun & Surf | 2005 | IGT International Game Technologies Reno, NV, USA |
| Medal video game | Sun Flower | 2005 | Unknown Korea |
| Nintendo GBA cart. | Super Army War Model AGB-BG6E-USA | 2005 | Atlus USA, Inc. CA, USA |
| Slot Machine | Super Credits | 2005 | WMS Gaming, Inc. Chicago, IL, USA |
| Nintendo GBA cart. | Super Donkey Kong 3 Model AGB-BDQJ-JPN | 2005 | Nintendo Co., Ltd. Japan |
