| Tomy Evio cart. |  I Love Classic 1 Model eM4 | 2003 | Tomy |
| Tomy Evio cart. | I Love Classic 2 Model eM12 | 2003 | Tomy |
| LeapFrog Leapster cart. | I Spy - Treasure Hunt | 2003 | LeapFrog |
| PC/MS-Windows CD | I Was An Atomic Mutant | 2003 | ValuSoft |
| Nintendo GameCube disc | I-Ninja Model DOL-GNJE-USA | 2003 | NAMCO Hometek, Ltd. USA |
| Redemption mechanical game | Ice Cold Beer | 2003 | ICE Innovative Concepts in Ent. Buffalo, NY, USA |
| Nintendo GBA cart. | Ice Nine Model AGB-AR3E-USA | 2003 | BAM! Ent. |
| LeapFrog Little Touch LeapPad cart. | If I were... Model 500-11468 | 2003 | LeapFrog |
| Sony PlayStation CD | IK+ Model SLES-04040 | 2003 | Ignition Ent., Ltd. |
| Nintendo GameCube disc | Ikaruga Model DOL-GIKE-USA | 2003 | Infogrames, Inc. NY, USA 22242 |
| Nintendo GameCube disc | Ikaruga Model DOL-GIKJ-JPN | 2003 | Atari, Inc. NY, USA |
| Nintendo GameCube disc | Ikaruga Model DOL-GIKP-UKV | 2003 | Atari Europe S.A.S.U. |
| Nintendo GameCube disc | Ikaruga Model DOL-GSSP-EUR | 2003 | Atari Europe S.A.S.U. |
| PC/MS-Windows CD | IL-2 Sturmovik - Forgotten Battles | 2003 | Ubisoft Ent. Montreuil sous Bois, France |
| PC/MS-Windows CD | In Memoriam | 2003 | Ubisoft Ent. Montreuil sous Bois, France |
| Slot Machine | In the Money | 2003 | Bally Gaming, Inc. Las Vegas, NV, USA |
| Arcade Video game | Incoming | 2003 | Global VR San Jose, CA, USA |
| Slot Machine | Independence Pay 2-Coin Multiplier | 2003 | Bally Gaming, Inc. Las Vegas, NV, USA |
| Video Slot Machine | Indian Dreaming 2nd Chance | 2003 | Aristocrat Leisure Industries Pty, Ltd. |
| Video Slot Machine | Indian Dreaming Lady Luck | 2003 | Aristocrat Leisure Industries Pty, Ltd. |
| Video Slot Machine | Indian Princess | 2003 | Aristocrat Leisure Industries Pty, Ltd. |
| Pachinko | Indian Uso Tsukanai | 2003 | Newgin Japan |
| PC/MS-Windows CD | Indiana Jones and the Emperor's Tomb | 2003 | LucasArts Ent. Co. |
| Pachinko | Inoshishi Ou | 2003 | Sansei R&D Japan |
| Sega Dreamcast GD | Interlude Model T-20117M | 2003 | Nec InterChannel, Ltd. Japan |
| Sega Dreamcast GD | Interlude Model T-20127M | 2003 | Nec InterChannel, Ltd. Japan |
| Sony PlayStation 2 disc | International Cue Club Model SLES-50914 | 2003 | Midas Int. Ent. |
| Nintendo GBA cart. | International Karate Plus Model AGB-A3KE-USA | 2003 | Ignition Ent., Ltd. |
| Nintendo GBA cart. | International Karate Plus Model AGB-A3KP-EUR | 2003 | Ignition Ent., Ltd. |
| Sony PlayStation 2 disc | International Pool Championship Model SLES-51629 | 2003 | Play It |
| Nintendo GBA cart. | International Superstar Soccer Advance Model AGB-AY2P-EUR | 2003 | Konami Corp. Japan |
| Sony PlayStation CD |  Inuyasha - A Feudal Fairy Tale Model SLUS-01534 | 2003 | Bandai America, Inc. 45557 |
| Nintendo GBA cart. | Inuyasha - Naraku no Wana! Mayoi no Mori no Shoutaijou Model AGB-AIYJ-JPN | 2003 | Takara Co., Ltd. Japan |
| Nintendo GBA cart. | Iridion II Model AGB-AI2E-USA | 2003 | Majesco Sales, Inc. |
| Nintendo GBA cart. | Iridion II Model AGB-AI2P | 2003 | Vivendi Universal Games, Inc. |
| Sega Dreamcast GD | Iris Model T-19721M | 2003 | KID Kindle Imagine Develop |
| Pachinko | Iruna Bomber | 2003 | Sansei R&D Japan |
| Slot Machine | It's All Greek to Me | 2003 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | It's My Party! | 2003 | IGT International Game Technologies Reno, NV, USA |
| Takara e-Kara MC series cart. | J-Pop Mix Mini Vol. 1 Model MC0009-JPM | 2003 | Takara Co., Ltd. Japan |
