| LeapFrog Leapster cart. |  Disney·Pixar Buscando a Nemo - Leer Bajo el Mar | 2003 | LeapFrog |
| Slot Machine | Dizzy Dough | 2003 | WMS Gaming, Inc. Chicago, IL, USA |
| Fruit Machine | Do$h 'n' Pecks | 2003 | Barcrest Games |
| Sony PlayStation 2 disc | DoDonPachi Dai-Ou-Jou Model SLPS-25233 | 2003 | Arika Japan |
| Slot Machine | Dog and Bone | 2003 | GTech Corp. Providence, RI, USA |
| Redemption mechanical game | Doki Doki Mario Chance | 2003 | Banpresto Japan |
| Nintendo GBA cart. | Dokidoki Cooking Series 2 - Gourmet Kitchen - Suteki na Obentou Model AGB-A8OJ-JPN | 2003 | MTO, Inc. Japan |
| Coin-op Misc. game | Doko-Doko House | 2003 | Komaya Co., Ltd. Japan |
| Sammy Atomiswave cart. | Dolphin Blue | 2003 | Sammy Corp. Japan |
| Pachislot | Don Don King | 2003 | Daido |
| LeapFrog Leapster cart. | Don Lápiz - Aprender a Dibujar y Escribir | 2003 | LeapFrog |
| MSX 2 disk | Don't Warro! Be Japo! Hb | 2003 | Paxanga Soft |
| Seta Aleck64 cart. | Donchan Puzzle Hanabi de Doon! | 2003 | Aruze Corp. Japan |
| Nintendo GBA cart. | Donkey Kong Country Model AGB-A5NE-USA | 2003 | Nintendo of America, Inc. USA 45496 |
| Nintendo GBA cart. | Donkey Kong Country Model AGB-A5NP | 2003 | Nintendo Co., Ltd. Japan |
| Nintendo GameCube disc | Donkey Konga | 2003 | Nintendo Co., Ltd. Japan |
| Nintendo GameCube disc | Donkey Konga Model DOL-GKGE-USA | 2003 | Nintendo of America, Inc. USA 45496 |
| Nintendo GBA cart. | Dora the Explorer - Super Spies Model AGB-BERE-USA | 2003 | Take-Two Interactive |
| Sega Pico game | Doraemon - Chiiku Asobi Dora-Land Model T-226100 | 2003 | Shogakukan Production |
| Sega Pico game |  Doraemon Ensoku-Imohori-Undoukai | 2003 | Shogakukan Production |
| Nintendo Game Boy Color cart. | Doraemon no Study Boy - Kanji Yomikaki Master Model CGB-BCYJ-JPN | 2003 | Shogakukan Production |
| Pachinko | Doremi Tengoku | 2003 | Daiichi Denshi |
| Pachislot | Doronjo | 2003 | Heiwa Japan |
| Slot Machine | Double Bucks Deluxe Classics | 2003 | IGT International Game Technologies Reno, NV, USA |
| Video Slot Machine | Double Challenge | 2003 | Amcoe, Inc. USA |
| Slot Machine | Double Chance Poker | 2003 | Andamiro Co., Ltd. |
| Slot Machine | Double Diamond - Spin 'n' Hold | 2003 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Double Diamond Run | 2003 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Double Dollars Fast-Hit | 2003 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Double Dollars Red White & Blue | 2003 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Double Double Diamond Luck | 2003 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Double Down Stud | 2003 | IGT International Game Technologies Reno, NV, USA |
| Nintendo GBA cart. | Double Dragon Advance Model AGB-BDDE-USA | 2003 | Atlus USA, Inc. CA, USA |
| Slot Machine | Double Magic Classics | 2003 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Double Red White & Blue - Quarter Mania | 2003 | IGT International Game Technologies Reno, NV, USA |
| Pachislot | Double-X | 2003 | Net Corp. Japan |
| Medal video game | Doubles IV+ | 2003 | Unknown Korea |
| Medal video game | Doubles V | 2003 | Unknown Korea |
| Sony PlayStation CD | Doubutsu Chara Navi Uranai 2: Kosei Shinrigaku + Ren'ai Uranai Puzzle Model SLPS-03526 | 2003 | Culture Brain |
| Nintendo GameCube disc | Doubutsu no Mori e+ | 2003 | Nintendo Co., Ltd. Japan |
