| Video Slot Machine |  Europa 2002 | 2001 | Nazionale Elettronica Giochi Italy |
| PC/MS-Windows CD | Europa Universalis II | 2001 | Strategy First |
| Sony PlayStation CD | Europe Racer Model SLES-03415 | 2001 | Davilex |
| Nintendo Game Boy Color cart. | European Super League | 2001 | Virgin Interactive Ent., Ltd. UK 013715 |
| PC/MS-Windows CD | European Super League | 2001 | Virgin Interactive Ent., Ltd. UK 013715 |
| Nintendo GBA cart. | European Super League Model AGB-AELP-EUR | 2001 | Virgin Interactive Ent., Ltd. UK 013715 |
| Sony PlayStation CD | European Super League Model SLES-03082 | 2001 | Virgin Interactive Ent., Ltd. UK 013715 |
| Sega Dreamcast GD | European Super League Model T-7015D-50 | 2001 | Virgin Interactive Ent., Ltd. UK 013715 |
| Arcade Video game | EuroPlay 2001 | 2001 | SLEIC Creaciones E Investigaciones Electronicas, S.L. Spain |
| Sony PlayStation CD | EVE - The Fatal Attraction Model SLPM-86826~28 | 2001 | Gamevillage |
| Sega Dreamcast GD | Eve Zero - Ark of the Matter Model T-39802M | 2001 | NetVillage Japan |
| Sony PlayStation CD |  Eve Zero Model SLPM-86976~8 | 2001 | Gamevillage |
| Sony PlayStation CD | Evergreen Avenue Model SLPS-03278 | 2001 | Datam Polystar |
| PC/MS-Windows CD | EverQuest - The Shadows of Luclin | 2001 | Sony Online Ent., Inc. |
| PC/MS-Windows CD | Evil Dead - Hail to the King | 2001 | T-HQ, Inc. Toy HeadQuarters |
| Sony PlayStation CD |  Evil Dead - Hail to the King Model SLES-03428/13428 | 2001 | T-HQ, Inc. Toy HeadQuarters |
| Sega Dreamcast GD | Evil Dead - Hail to the King Model T-10005D-80 | 2001 | T-HQ, Inc. Toy HeadQuarters |
| PC/MS-Windows CD | Evil Twin - Cyprien's Chronicles | 2001 | UBI Soft Creteil, France 307211 |
| Sega Dreamcast GD | Evolution 2 - Far Off Promise Model T-45005D-50 | 2001 | UBI Soft Creteil, France 307211 |
| Nintendo GBA cart. | EX Monopoly Model AGB-AMOJ-JPN | 2001 | Takara Co., Ltd. Japan |
| Slot Machine | Excellent | 2001 | Unknown Korea |
| Sony PlayStation CD | Exciting Bass 3 Model SLPM-86729 | 2001 | Konami Corp. Japan |
| Nintendo GBA cart. | Exciting Bass Model AGB-AMGJ-JPN | 2001 | Konami Corp. Japan |
| Sony PlayStation CD | Exciting Pro Wres 2 Model SLPS-03122 | 2001 | Yuke's Japan |
| Pachislot | Exhaust | 2001 | Heiwa Japan |
| Sega Dreamcast GD | Exodus Guilty Neos Model T-44404M | 2001 | Abel |
| Nintendo GBA cart. | Expedition der Stachelbeeren - Zoff im Zoo | 2001 | T-HQ, Inc. Toy HeadQuarters |
| PC/MS-Windows CD | Exploman | 2001 | CDV Soft. Ent. USA, Inc. |
| Pachislot | Explorer | 2001 | Bellco Corp. Japan |
| Slot Machine | Extrema Draw Poker | 2001 | Extrema Intersystems |
| Nintendo Game Boy Color cart. | Extreme Ghostbusters Model CGB-BEBP-EUR | 2001 | LSP Light & Shadow Production |
| Dragon cass. | Eye-Spy Hb | 2001 | Crandall, David |
| Nintendo GBA cart. | EZ-Talk - Shokyuu-Hen 1 Model AGB-A22J-JPN | 2001 | Keynet, Inc. Japan |
| Nintendo GBA cart. | EZ-Talk - Shokyuu-Hen 2 Model AGB-A23J-JPN | 2001 | Keynet, Inc. Japan |
| Nintendo GBA cart. | EZ-Talk - Shokyuu-Hen 3 Model AGB-A24J-JPN | 2001 | Keynet, Inc. Japan |
| Nintendo GBA cart. | EZ-Talk - Shokyuu-Hen 4 Model AGB-A25J-JPN | 2001 | Keynet, Inc. Japan |
| Nintendo GBA cart. | EZ-Talk - Shokyuu-Hen 5 Model AGB-A26J-JPN | 2001 | Keynet, Inc. Japan |
| Nintendo GBA cart. | EZ-Talk - Shokyuu-Hen 6 Model AGB-A27J-JPN | 2001 | Keynet, Inc. Japan |
| Arcade Video game | Ez2dancer 2nd Move | 2001 | Amuse World Corp. Seoul, Korea |
| Arcade Video game | Ez2DJ 3rd TraX: Absolute Pitch | 2001 | Amuse World Corp. Seoul, Korea |
