| Pachislot |  Deka Donchan | 2001 | Aruze Corp. Japan |
| Pachislot | Delta Storm | 2001 | Abilit Japan |
| Pachinko | Demae Icchou | 2001 | Sansei R&D Japan |
| Sony PlayStation CD |  Dengeki PlayStation D43 Model SLPM-80612 | 2001 | Media Works Japan |
| Sony PlayStation CD | Dengeki PlayStation D44 Model SLPM-80615 | 2001 | Media Works Japan |
| Sony PlayStation CD | Dengeki PlayStation D45 Model SLPM-80618 | 2001 | Media Works Japan |
| Sega Dreamcast GD |  Dengen Tenshi Taisen Mahjong Shangri-La Model T-40803M | 2001 | Marvelous Ent., Inc. |
| Sky Gamestar game | Denki Blocks! | 2001 | Sky Games |
| Nintendo GBA cart. | Denki Blocks! Model AGB-ADBE-USA | 2001 | Majesco Sales, Inc. |
| Nintendo GBA cart. | Denki Blocks! Model AGB-ADBP | 2001 | Rage |
| Nintendo Game Boy Color cart. | denki Blocks! Model CGB-BD9P-EUR | 2001 | Rage |
| Sony PlayStation CD | Derby Jockey 2001 Model SLPS-03131 | 2001 | Asmik Ace Ent., Inc. Japan |
| Arcade Video game | Derby Owners Club II | 2001 | SEGA Corp. |
| Arcade Video game | Derby Owners Club World Edition | 2001 | SEGA Corp. |
| Nintendo 64 cart. | Derby Stallion 64 Model NUS-NDAJ | 2001 | Media Factory Japan |
| Sega Dreamcast GD | Derby Tsuku 2 Model HDR-0167 | 2001 | SEGA Corp. |
| PC/MS-Windows CD | Desblood Racer | 2001 | Illusion Japan |
| Commodore Amiga CD | Descent - Freespace - The Great War | 2001 | Interplay |
| PC/MS-Windows CD | Desperados - Wanted Dead or Alive | 2001 | Infogrames Interactive, Inc. 329720 |
| Nintendo GBA cart. | Dexter's Laboratory - Deesaster Strikes! Model AGB-ADLE-USA | 2001 | BAM! Ent. |
| Nintendo GBA cart. |  Dexter's Laboratory - Deesaster Strikes! Model AGB-ADLP | 2001 | BAM! Ent. |
| Sega Dreamcast GD | Di Gi Charat Fantasy Model T-46301M | 2001 | Broccoli Japan |
| Sega Dreamcast GD | Di Gi Charat Fantasy Model T-46302M | 2001 | Broccoli Japan |
| PC/MS-Windows CD | Diablo II - Lord of Destruction | 2001 | Blizzard Ent., Inc. |
| Nintendo GBA cart. | Diadroids World - Evil Teikoku no Yabou Model AGB-ADDJ-JPN | 2001 | Epoch Co., Ltd. Tokyo, Japan |
| Slot Machine | Diamonds 4 Ever | 2001 | WMS Gaming, Inc. Chicago, IL, USA |
| Slot Machine | Dick Clark's Censored Bloopers | 2001 | IGT International Game Technologies Reno, NV, USA |
| Nintendo GBA cart. |  Diddy Kong Pilot | 2001 | Nintendo Co., Ltd. Japan |
| Nintendo Game Boy Color cart. | Die Maus - Verrückte Olympiade Model CGB-BVOD-NOE | 2001 | Infogrames Interactive, Inc. 329720 |
| Sony PlayStation CD | Die Millionen Show Model SLES-03588 | 2001 | Unknown |
| Nintendo Game Boy Color cart. | Die Monster AG Model CGB-B4QD-NOE | 2001 | T-HQ, Inc. Toy HeadQuarters |
| Arcade Video game | Diet Family | 2001 | SemiCom Seoul, Korea |
| PC/MS-Windows CD | Dig Dug Deeper | 2001 | Infogrames Interactive, Inc. 329720 |
| Nintendo Game Boy Color cart. | Digimon Adventure 2001 | 2001 | BBD |
| Sony PlayStation CD | Digimon Digital Card Battle Model SLUS-01328 | 2001 | Bandai America, Inc. 45557 |
| Sony PlayStation CD | Digimon Tamers - Battle Evolution Model SLPS-03357 | 2001 | Bandai Co., Ltd. Japan |
| Bandai WonderSwan Color cart. | Digimon Tamers - Battle Spirit Model SWJ-BANC1A | 2001 | Bandai Co., Ltd. Japan |
| Bandai WonderSwan Color cart. | Digimon Tamers - Brave Tamer Model SWJ-BANC1D | 2001 | Bandai Co., Ltd. Japan |
| Bandai WonderSwan Color cart. | Digimon Tamers - Digimon Medley Model SWJ-BANC14 | 2001 | Bandai Co., Ltd. Japan |
| Sony PlayStation CD | Digimon Tamers - Pocket Culumon Model SLPS-03211 | 2001 | Bandai Co., Ltd. Japan |
