| Pachislot |  Cherry Travel | 2001 | EMA Japan |
| Sony PlayStation CD |  Chess Model SLUS-01400 | 2001 | A1 Games |
| Sony PlayStation CD | Chi Vuol Essere Miliardario? Model SLES-03582 | 2001 | Eidos Interactive |
| Nintendo Game Boy Color cart. | Chibi Maruko-chan - Go Chounai Minna de Game dayo! Model CGB-BCNJ-JPN | 2001 | Epoch Co., Ltd. Tokyo, Japan |
| Redemption mechanical game | Chibi-Pocket | 2001 | Yuvo |
| Sony PlayStation CD | Chiki Chiki Machine Mou Race - Wacky Races Model SLPM-86845 | 2001 | Hudson Soft. Hudson Group Japan |
| Nintendo Game Boy Color cart. | Chiki Chiki Machine Mou Race Model CGB-AW9J-JPN | 2001 | Syscom Ent. Japan |
| Slot Machine | Chinese Laundry | 2001 | IGT International Game Technologies Reno, NV, USA |
| Nintendo GBA cart. | Chinmoku no Iseki - Estpolis Gaiden Model AGB-AGDJ-JPN | 2001 | Taito Corp. Japan |
| Medal video game | Choice III - Joker's Dream | 2001 | SemiCom Seoul, Korea |
| Nintendo GBA cart. | Choro Q Advance Model AGB-AQAJ-JPN | 2001 | Takara Co., Ltd. Japan |
| Sony PlayStation CD |  Chou Aniki - Kyukyoku Muteki Ginga Saikyo Otoko Model SLPM-86873 | 2001 | Four Winds |
| Sega Dreamcast GD | Choukou Senki Kikaioh for Matching Service Model T-1232M | 2001 | Capcom Co., Ltd. Japan |
| Nintendo GBA cart. | ChuChu Rocket! Model AGB-ACRE-USA | 2001 | SEGA Corp. |
| Nintendo GBA cart. | ChuChu Rocket! Model AGB-ACRJ-JPN | 2001 | SEGA Corp. |
| Nintendo GBA cart. | ChuChu Rocket! Model AGB-ACRP | 2001 | SEGA Corp. |
| PC/MS-Windows CD | CIA Operative - Solo Missions | 2001 | Infogrames Interactive, Inc. 329720 |
| PC/MS-Windows CD | Civilization III | 2001 | Atari Interactive, Inc. |
| Fruit Machine | Classic Adders & Ladders | 2001 | BWB |
| Handheld game | Classic Baseball Model 43386 | 2001 | Mattel Electronics Mattel, Inc. |
| Sony PlayStation CD | Cleopatra Fortune Model SLPS-03187 P | 2001 | Altron Corp. |
| Sega Dreamcast GD | Cleopatra Fortune Model T-16603M P | 2001 | Altron Corp. |
| Fruit Machine | Cliffhanger | 2001 | Vivid Gaming England |
| Pachislot | Climax | 2001 | Aruze Corp. Japan |
| Slot Machine | Clint Eastwood - For A Few Dollars More | 2001 | WMS Gaming, Inc. Chicago, IL, USA |
| Sega Dreamcast GD | Close To - Inori no Oka Model T-19704M | 2001 | KID Kindle Imagine Develop |
| Fruit Machine | Club Big Money | 2001 | Crystal Leisure |
| Arcade Video game | Club Kart | 2001 | SEGA Corp. |
| PC/MS-Windows CD | Codename - Outbreak | 2001 | Virgin Interactive Ent., Ltd. UK 013715 |
| Arcade Video game | Coinmaster Roulette | 2001 | Coinmaster |
| Nintendo Game Boy Color cart. | Colin McRae Rally Model CGB-BCOP-EUR | 2001 | T-HQ, Inc. Toy HeadQuarters |
| Fruit Machine | Coliseum Cash | 2001 | JPM International |
| PC/MS-Windows CD | Collector | 2001 | Mink Japan |
| Pachislot | Colombus 1492 | 2001 | Daito-Giken, Inc. Japan |
| Arcade Video game | Colorama | 2001 | Coinmaster |
| Redemption mechanical game | Colorama II | 2001 | Bromley, Inc. Elk Grove Village, IL, USA |
| Sony PlayStation CD | Colorful Logic 2 Model SLPS-03115 | 2001 | Altron Corp. |
| Sony PlayStation CD | Colorful Logic 3 - Fushigi na Henkei Logic Model SLPS-03239 | 2001 | Altron Corp. |
| Slot Machine | Columbus | 2001 | IGT International Game Technologies Reno, NV, USA |
| Nintendo GBA cart. | Columns Crown Model AGB-ACGE-USA | 2001 | SEGA Corp. |
