| Sony PlayStation CD |  Dengeki PlayStation D21 Model SLPM-80457 | 2000 | Media Works Japan |
| Sony PlayStation CD | Dengeki PlayStation D32 Model SLPM-80557 | 2000 | Media Works Japan |
| Sony PlayStation CD | Dengeki PlayStation D33 Model SLPM-80562 | 2000 | Media Works Japan |
| Sony PlayStation CD | Dengeki PlayStation D34 Model SLPM-80569 | 2000 | Media Works Japan |
| Sony PlayStation CD | Dengeki PlayStation D35 Model SLPM-80574 | 2000 | Media Works Japan |
| Sony PlayStation CD | Dengeki PlayStation D36 Model SLPM-80578 | 2000 | Media Works Japan |
| Sony PlayStation CD | Dengeki PlayStation D37 Model SLPM-80582 | 2000 | Media Works Japan |
| Sony PlayStation CD | Dengeki PlayStation D38 Model SLPM-80589 | 2000 | Media Works Japan |
| Sony PlayStation CD | Dengeki PlayStation D39 Model SLPM-80603 | 2000 | Media Works Japan |
| Sony PlayStation CD | Dengeki PlayStation D41 Model SLPM 80607 | 2000 | Media Works Japan |
| Sony PlayStation CD | Dengeki PlayStation D42 Model SLPM-80611 | 2000 | Media Works Japan |
| Sony PlayStation CD |  Denkousekka Micro Runner - Maniac Hakase no Hisaku Model SLPS-02851 | 2000 | Spike Japan |
| PC/MS-Windows CD |  Dennou M Dorei - Reimi Model WILL-033 18 | 2000 | Guilty Japan |
| SNK Neo-Geo Pocket Color cart. | Densetsu no Ogre Battle Gaiden - Zenobia no Ouji Model NEOP00850 | 2000 | SNK Corp. Shin Nihon Kikaku Japan |
| Sega Dreamcast GD | Densha de Go! 2 - Kousoku-hen 3000 Bandai Model T-1102M | 2000 | Taito Corp. Japan |
| Nintendo Game Boy Color cart. | Densha de Go! 2 Model CGB-B82J-JPN | 2000 | CyberFront Corp. Japan |
| Arcade Video game | Densha De Go! 3 Tsukin-hen | 2000 | Taito Corp. Japan |
| Arcade Video game | Densha De Go! 3 Tsukin-hen Daiya Kaisei | 2000 | Taito Corp. Japan |
| Sony PlayStation CD | Densha de Go! Nagoya Tetsudou-hen Model SLPM-86424 | 2000 | Taito Corp. Japan |
| Arcade Video game | Densha de Go! Ryojo-hen | 2000 | Taito Corp. Japan |
| Nintendo Game Boy Color cart. | Der König der Löwen - Simbas grosses Abenteuer Model CGB-BLKD-NOE | 2000 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Arcade Video game | Derby Owners Club 2000 | 2000 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Dreamcast GD | Derby Tsuku - Derby Ba wo Tsukurou! Taikenban | 2000 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Dreamcast GD | Derby Tsuku - Derby Ba wo Tsukurou! Model HDR-0084 | 2000 | SEGA Enterprises, Ltd. Tokyo, Japan |
| PC/MS-Windows CD | Des Blood 3 | 2000 | Illusion Japan |
| PC/MS-Windows CD | Descent³ - Mercenary | 2000 | Interplay |
| Sega Dreamcast GD | deSPIRIA Taikenban | 2000 | Atlus Co., Ltd. Japan |
| Sega Dreamcast GD | deSPIRIA Model T-14402M | 2000 | Atlus Co., Ltd. Japan |
| Sony PlayStation CD | Destruction Derby Raw demo Model SLUS-90092 | 2000 | Midway Home Ent. |
| Sony PlayStation CD | Destruction Derby Raw Model SCES-02060 | 2000 | Psygnosis, Ltd. |
| Sony PlayStation CD | Destruction Derby Raw Model SLUS-00912 | 2000 | Midway Home Ent. |
| Sony PlayStation CD | Detective Barbie - The Mystery Cruise Model SLUS-01221 | 2000 | Mattel Interactive Mattel, Inc. |
| Sony PlayStation CD |  Deuce Prototype | 2000 | Midway Home Ent. |
| PC/MS-Windows CD | Deus Ex | 2000 | Eidos Interactive |
| Sony PlayStation CD | DevilMan Model SLPS-02275 | 2000 | Bandai Co., Ltd. Japan |
| Nintendo Game Boy Color cart. | Dexter's Laboratory - Robot Rampage Model CGB-BROE-USA | 2000 | BAM! Ent. |
| PC/MS-Windows CD | Diablo II | 2000 | Blizzard Ent., Inc. |
| Slot Machine | Diamond Cinema Bogart and Bergman | 2000 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Diamond Cinema Frank Sinatra | 2000 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Diamond Cinema Marilyn Monroe | 2000 | IGT International Game Technologies Reno, NV, USA |
