| SNK Neo-Geo Pocket Color cart. |  Bikkuriman 2000 - Viva! Pocket Festiva! Model NEOP00830 | 2000 | SEGA Toys |
| PC/MS-Windows CD | Biko 2 - Reversible Face | 2000 | Illusion Japan |
| Nintendo Game Boy Color cart. | Binary Monster 2 -Adventure of Hell | 2000 | Gowin Taiwan |
| Slot Machine | Bingo + | 2000 | AGI Austrian Gaming Industries Novomatic Group |
| Medal video game | Bingo Party Special | 2000 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Video Slot Machine | Bingo Slot | 2000 | Unidesa Universal de Desarrollos Electronicos |
| Sega Dreamcast GD | Biohazard - Code: Veronica Shokai Genteiban | 2000 | Capcom Co., Ltd. Japan |
| Sony PlayStation CD | BioHazard - Gun Survivor Model SLPS-02553 | 2000 | Capcom Co., Ltd. Japan |
| Nintendo 64 cart. | BioHazard 2 Model NUS-NB5J | 2000 | Capcom Co., Ltd. Japan |
| Nintendo Game Boy Color cart. | Bionic Commando - Elite Forces Model CGB-AV4E-USA | 2000 | Nintendo of America, Inc. USA 45496 |
| Nintendo Game Boy Color cart. |  Bionic Commando - Elite Forces Model CGB-AV4P-AUS | 2000 | Nintendo Co., Ltd. Japan |
| Sony PlayStation CD | Bishi Bashi Special 3 - Step Champ Model SLPM-86539 | 2000 | Konami Corp. Japan |
| Sony PlayStation CD | Bishi Bashi Special Model SLES-02537 | 2000 | Konami Corp. Japan |
| Sony PlayStation CD | Bishoujo Ren'ai Mahjong Series: Karan Koron Gakuen - Doki Doki-hen Model SLPM-86414 | 2000 | J-Wing |
| Sony PlayStation CD | Bishoujo Ren'ai Mahjong Series: Karan Koron Gakuen - Munekyun-hen Model SLPM-86468 | 2000 | J-Wing |
| Sony PlayStation CD | Bishoujo Ren'ai Mahjong Series: Karan Koron Gakuen - Pure Love-hen Model SLPM-86474 | 2000 | J-Wing |
| Pachislot | Black Jack | 2000 | Net Corp. Japan |
| Pachislot | Black Russian | 2000 | Baltec Japan |
| Sony PlayStation CD | Black/Matrix Cross Model SLPS-02962~3 | 2000 | Nec InterChannel, Ltd. Japan |
| Sony PlayStation CD | Blackjack vs. Matsuda Jun Model SLPS-01983 | 2000 | Pony Canyon, Inc. Japan |
| Sony PlayStation CD | Blade Arts - Tasogare no Miyako R'lyeh Model SLPM-86602 | 2000 | Enix, Ltd. Japan |
| Nintendo Game Boy Color cart. | Blade Model CGB-BLEE-USA | 2000 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Nintendo Game Boy Color cart. | Blade Model CGB-BLEP-EUR | 2000 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Sony PlayStation CD | Blade Model SLES-03213 | 2000 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Sony PlayStation CD | Blade Model SLES-03214 | 2000 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Sony PlayStation CD | Blade Model SLES-03215 | 2000 | Activision, Inc. Los Angeles, CA, USA 47875 |
| Sony PlayStation CD | Blade Model SLUS-01215 | 2000 | Activision, Inc. Los Angeles, CA, USA 47875 |
| PC/MS-Windows CD | Blair Witch Vol. I - Rustin Parr | 2000 | Take-Two Interactive |
| PC/MS-Windows CD | Blair Witch Vol. III - The Elly Kedward Tale | 2000 | Take-Two Interactive |
| PC/MS-Windows CD | Blair Witch, Volume II - The Legend of Coffin Rock | 2000 | Gathering of Developers, Inc. |
| Sony PlayStation CD | Blaster Master - Blasting Again Model SLES-02273 | 2000 | SUNSOFT Kounan, Japan |
| Nintendo Game Boy Color cart. | Blaster Master - Enemy Below Model DMG-AEHE-USA | 2000 | SUNSOFT Sun Corp. of America IL, USA |
| Nintendo Game Boy Color cart. | Blaster Master - Enemy Below Model DMG-AEHP-EUR | 2000 | SUNSOFT Kounan, Japan |
| Sony PlayStation CD | Blaster Master Model SLPS-02617 | 2000 | SUNSOFT Kounan, Japan |
| Sony PlayStation CD | Blend X Brand - Odekake Gousei RPG Model SLPS-02818 | 2000 | Tonkin House Japan |
| Sony PlayStation CD | Block Kuzushi - Kowashite Help! Model SLPS-03042 | 2000 | Media Gallop Japan |
| Sony PlayStation CD | Block Kuzushi 2 Model SLPS-02578 | 2000 | Marvelous Ent., Inc. |
| MSX 2 disk | Blue Warrior Hb | 2000 | Moai Tech |
| PC/MS-Windows CD | Blue's Reading Time Activities | 2000 | Humongous Ent., Inc. |
| Nintendo 64 cart. | Blues Brothers 2000 | 2000 | Titus Gagny, France |
