| Sega Saturn CD |  Shining the Holy Ark | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Shinrei Jusatsushi Taroumaru | 1997 | Time Warner Interactive |
| Sega Saturn CD | Shinseiki Evangelion - 2nd Impression | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Shinsetsu Samurai Spirits - Bushidoh Retsuden | 1997 | SNK Corp. Shin Nihon Kikaku Japan |
| Sega Saturn CD | Shutsudou! Mini-skirt Police | 1997 | Sada Soft Genki |
| Sega Saturn CD | Sid Meier's Civilization - Shin Sekai Shichi Dai Bunmei Model T-2003G | 1997 | Asmik Co., Ltd. Japan |
| Sega Saturn CD | Side Pocket 3 | 1997 | Data East Corp. Japan |
| Sega Saturn CD |  Side Pocket 3 Sample | 1997 | Data East Corp. Japan |
| Sega Saturn CD | Silhouette Mirage Taikan CD-ROM Sousa Setsumei Model 610-6679 | 1997 | ESP Ent. Soft. Publishing |
| Sega Saturn CD | Silhouette Mirage Model T-32901G | 1997 | ESP Ent. Soft. Publishing |
| Sega Saturn CD | Simulation Zoo | 1997 | Softbank Corp. Japan |
| Sega Saturn CD | Skeleton Warriors | 1997 | Virgin Interactive Ent., Ltd. UK 013715 |
| Sega Saturn CD | Skull Fang - Kuuga Gaiden Model T-1311G | 1997 | Data East Corp. Japan |
| Sega Saturn CD | Sky Target | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sky Target | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sky Target | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Slayers Royal Model T-27903G | 1997 | Kadokawa Shoten Japan |
| Sega Saturn CD |  Sonic 3D - Flickies' Island Model MK81062-50 | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sonic Jam Model 81079 | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sonic Jam Model GS-9147 | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sonic Jam Model MK81079-50 | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sonic R Model 81800 | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sonic R Model GS-9170 | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sonic R Model MK-81800-50 | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Sotsugyou Crossworld | 1997 | Shogakukan Production |
| Sega Saturn CD | Sotsugyou Graduation S | 1997 | Nec InterChannel, Ltd. Japan |
| Sega Saturn CD | Soukuu no Tsubasa - Gotha World | 1997 | Micronet Co., Ltd. Japan |
| Sega Saturn CD | Soukyuugurentai Otokuyou Model T-10626G | 1997 | Electronic Arts Victor, Inc. Japan |
| Sega Saturn CD | Soukyuugurentai Model T-10616G | 1997 | Electronic Arts Victor, Inc. Japan |
| Sega Saturn CD | Soviet Strike | 1997 | Electronic Arts CA, USA 14633 |
| Sega Saturn CD | Söldnerschild | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Space Jam | 1997 | Acclaim Japan |
| Sega Saturn CD | Space Jam | 1997 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Sega Saturn CD | Spot Goes to Hollywood Model T-7001H-50 | 1997 | Virgin Interactive Ent., Ltd. UK 013715 |
| Sega Saturn CD | Spot Goes to Hollywood Model T-7014G | 1997 | Virgin Interactive Ent., Ltd. UK 013715 |
| Sega Saturn CD | Stakes Winner 2 - Saikyouba Densetsu | 1997 | SNK Corp. Shin Nihon Kikaku Japan |
| Sega Saturn CD | Standby Say You! Shokai Gentei Special Package 2 | 1997 | Human Ent. Japan |
| Sega Saturn CD | Steep Slope Sliders | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Steep Slope Sliders | 1997 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Saturn CD | Steep Slope Sliders Hibaihin | 1997 | Pack In Soft. Japan |
