| Commodore Amiga 500 disk |  Elvira II - The Jaws of Cerberus Model 41104 | 1992 | Accolade, Inc. San Jose, CA, USA 15605 |
| Fujitsu FM Towns CD | Emerald Dragon | 1992 | Glodia Co., Ltd. Japan |
| Sega Mega Drive cart. | Empire of Steel | 1992 | Flying Edge |
| Commodore Amiga 500 disk | Epic | 1992 | Ocean Soft., Ltd. 13156 |
| NEC PC-9801 Series 5.25in. disk | Epic | 1992 | Imagineer Co., Ltd. Japan |
| NEC PC-9801 Series 3.5in. disk | Epic | 1992 | Imagineer Co., Ltd. Japan |
| Atari ST disk | Epic | 1992 | Ocean Soft., Ltd. 13156 |
| Commodore Amiga 600HD disk | Epic | 1992 | Ocean Europe, Ltd. |
| Atari ST disk | Erik | 1992 | Atlantis Soft. |
| Phillips CD-i disc | Ernte der Sonne - Vincent Van Gogh | 1992 | Philips Interactive Media, Inc. |
| Phillips CD-i disc | Escape from CyberCity Model 310690071-2 | 1992 | Philips Interactive Media, Inc. |
| Nintendo Famicom cart. | Esper Dream 2 - Aratanaru Tatakai Model RC861 | 1992 | Konami Co., Ltd. Japan |
| IBM PC/AT DOS 3.5in. disk | Eternam | 1992 | Infogrames Interactive, Inc. 329720 |
| IBM PC/AT DOS 3.5in. disk |  Eternam | 1992 | Capstone |
| IBM PC/AT DOS 5.25in. disk | Eternam | 1992 | Erbe Soft. Spain |
| IBM PC/AT DOS 3.5in. disk | Eternam | 1992 | Erbe Soft. Spain |
| Atari 400/800 disk | Eureka! | 1992 | Mirage |
| Arcade Video game | Euro Champ '92 | 1992 | Taito Corp. Japan |
| Nintendo Super NES cart. | Euro Football Champ Model SNSP-HT | 1992 | Taito Corp. Japan |
| Commodore Amiga 500 disk | Euro Soccer | 1992 | Flair Soft. |
| Fujitsu FM Towns CD | Europa Sensen P | 1992 | KOEI Co., Ltd. Japan |
| NEC PC-9801 Series 3.5in. disk | Europa Sensen P | 1992 | KOEI Co., Ltd. Japan |
| NEC PC-9801 Series 5.25in. disk | Europa Sensen Model KN10221020 P | 1992 | KOEI Co., Ltd. Japan |
| MSX 2 disk | Europa Sensen Model KN10221040 P | 1992 | KOEI Co., Ltd. Japan |
| MSX 2 cart. | Europa Sensen Model KN10221050 P | 1992 | KOEI Co., Ltd. Japan |
| Sharp X68000 Series 5.25in. disk | Europa Sensen Model KN10221060 P | 1992 | KOEI Co., Ltd. Japan |
| Commodore Amiga 500 disk | European Championship 1992 | 1992 | Elite Systems, Ltd. |
| Atari ST disk | European Championship 1992 | 1992 | Tecmo, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | European Club Soccer | 1992 | Virgin Games, Ltd. UK 013715 |
| Commodore Amiga 500 disk | European Football Champ | 1992 | Domark Group, Ltd. |
| Atari ST disk | European Football Champ | 1992 | Domark Group, Ltd. |
| Sega Game Gear cart. | Evander Holyfield Boxing Model 2419-50 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Game Gear cart. | Evander Holyfield Boxing Model 2419 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Genesis cart. | Evander Holyfield's 'Real Deal' Boxing | 1992 | SEGA of America, Inc. San Francisco, CA, USA |
| MSX 2 disk | Evil Spirit | 1992 | BOF |
| Sega Genesis cart. | Ex-Mutants Model 1074 | 1992 | SEGA of America, Inc. San Francisco, CA, USA |
| Pachinko | Excite | 1992 | Fuji Shogi Co., Ltd. Japan |
| Nintendo Famicom cart. | Exciting Rally - World Rally Championship Model VRE-E2 | 1992 | Kaken Japan |
| IBM PC/AT DOS pack. | Executioners | 1992 | Bloodlust Soft. |
| Nintendo Super Famicom cart. | Exhaust Heat Model SHVC-EH | 1992 | Seta Co., Ltd. Japan |
