| NEC PC-9801 Series 5.25in. disk |  Aktie - Kabushiki Toushi Simulation Game | 1991 | Fuga System Japan |
| Nintendo Super Famicom cart. | Akumajou Dracula Model SHVC-AD | 1991 | Konami Co., Ltd. Japan |
| Atari ST disk | Alcantor | 1991 | Lankhor |
| Acorn Archimedes disk | Aldebaran | 1991 | Evolution Trading |
| IBM PC DOS pack. | Aldo Again Sw | 1991 | Ibach, David & Benjamin |
| IBM PC DOS pack. | Aldo's Assault Sw | 1991 | Ibach, David & Benjamin |
| NEC Supergraphx HuCARD | Aldynes Model HC91044 | 1991 | Hudson Soft. Hudson Group Japan |
| Sega Mega Drive cart. |  Alex Kidd in the Enchanted Castle | 1991 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Arcade Video game | Alexey Pajitnov's Welltris P | 1991 | Video System Co., Ltd. Kyoto, Japan |
| Sharp X68000 Series 5.25in. disk | Algarna | 1991 | Brother Kougyou Japan |
| Commodore Amiga 500 disk | Alianator | 1991 | CompuTec Verlag |
| Apple Macintosh CD | Alice - An interactive Museum Model TONP-1506 | 1991 | Toshiba EMI Japan |
| Fujitsu FM Towns CD | Alice no Yakata CD 18 | 1991 | Alicesoft Japan |
| Commodore C64 disk | Alien Attack | 1991 | Markt & Technik |
| Commodore Amiga 500 disk | Alien Breed | 1991 | Team 17 Soft., Ltd. |
| Commodore Amiga 500 disk | Alien Breed - Sory Disk | 1991 | Team 17 Soft., Ltd. |
| Commodore Amiga 500 disk | Alien Drug Lords - The Chyropian Connection | 1991 | Panther Games |
| Amstrad CPC cass. | Alien Legion | 1991 | Mega Soft Spain |
| Commodore C64 disk | Alien Science Quiz | 1991 | J&F Publishing, Inc. |
| Amstrad CPC cass. | Alien Storm P | 1991 | US Gold, Ltd. Birmingham, England 13442 |
| Sinclair ZX Spectrum cass. | Alien Storm P | 1991 | US Gold, Ltd. Birmingham, England 13442 |
| Sega Mega Drive cart. | Alien Storm P | 1991 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sinclair ZX Spectrum+3 disk | Alien Storm P | 1991 | Erbe Soft. Spain |
| Commodore C64 cass. | Alien Storm P | 1991 | US Gold, Ltd. Birmingham, England 13442 |
| Sega Mega Drive cart. | Alien Storm Model 1121-50 P | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Genesis cart. | Alien Storm Model 1121 P | 1991 | SEGA of America, Inc. San Francisco, CA, USA |
| Sega Mega-Tech cart. | Alien Storm Model 47 P | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Amstrad CPC/Spectrum+3 disk | Alien Storm Model 537961 P | 1991 | US Gold, Ltd. Birmingham, England 13442 |
| Sega Master System cart. | Alien Storm Model 7075 P | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Commodore Amiga 500 disk | Alien Storm Model 9698 P | 1991 | US Gold, Ltd. Birmingham, England 13442 |
| Amstrad CPC 464 disk | Alien Storm Model AMD-1191 P | 1991 | Erbe Soft. Spain |
| Sega Mega Drive cart. | Alien Storm Model G-4048 P | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Amstrad CPC 464 disk | Alien Tank Attack Hb | 1991 | Bollaware |
| Commodore C64 cass. | Alienworld | 1991 | Hi-Tec Soft. |
| Amstrad CPC type-in | Alinka | 1991 | Media Système Edition Gentilly, France |
| Amstrad CPC 464 disk | Alive | 1991 | Lankhor |
| Commodore Amiga CDTV CD | All Dogs Go To Heaven - Talking Electric Crayon | 1991 | Merit Soft. |
| Commodore Amiga 500 disk | All Dogs To Go Heaven - Electric Crayon Deluxe | 1991 | Merit Soft. |
| Orion-128 cass. | Almaz | 1991 | Unknown Russia |
| Commodore Amiga 500 disk | Alpha Waves | 1991 | Infogrames Interactive, Inc. 329720 |
