| Sinclair ZX Spectrum cass. |  Chubby Gristle | 1988 | Grandslam Ent., Ltd. |
| Sinclair ZX Spectrum cass. | Circus Games | 1988 | Tynesoft Computer Soft. |
| Sinclair ZX Spectrum cass. | Class 50 Rover | 1988 | Dee-Kay Systems |
| Sinclair ZX Spectrum cass. | Classic Arcadia - Triple Decker 4 Model AS221 | 1988 | Alternative Soft., Ltd. |
| Sinclair ZX Spectrum cass. |  Classic Arcadia Model 1STA-332 | 1988 | System 4 de Espana, S.A. Spain |
| Sinclair ZX Spectrum cass. | Classic Axiens | 1988 | Bubble Bus Soft. |
| Sinclair ZX Spectrum cass. | Clever & Smart | 1988 | Magic Bytes Germany |
| Sinclair ZX Spectrum cass. | Cloud 99 | 1988 | Marlin Games |
| Sinclair ZX Spectrum cass. | Coleccion De Exitos Dinamic | 1988 | Dinamic Soft. Madrid, Spain |
| Sinclair ZX Spectrum cass. | Coliseum | 1988 | Topo Soft. Spain |
| Sinclair ZX Spectrum cass. |  Commando | 1988 | Encore 012189 |
| Sinclair ZX Spectrum cass. | Commando Model LS-039 | 1988 | MCM Soft. Spain |
| Sinclair ZX Spectrum cass. | Conflict Command | 1988 | Ocean Soft., Ltd. 13156 |
| Sinclair ZX Spectrum cass. |  Crash issue 54: Sneak Preview 1 | 1988 | Crash, Ltd. |
| Sinclair ZX Spectrum cass. | Crash issue 58: Sneak Preview 2 | 1988 | Crash, Ltd. |
| Sinclair ZX Spectrum cass. | Crash issue 59: Sneak Preview 3 | 1988 | Crash, Ltd. |
| Sinclair ZX Spectrum cass. | Crazy Cars | 1988 | Titus Gagny, France |
| Sinclair ZX Spectrum cass. | Crazy Cars II | 1988 | Titus Gagny, France |
| Sinclair ZX Spectrum cass. | Cricket Captain Model SPFC | 1988 | D & H Games |
| Sinclair ZX Spectrum cass. | Cricket Crazy | 1988 | Dreaming Djinn, The |
| Sinclair ZX Spectrum cass. | Crime Busters | 1988 | Players Soft. |
| Sinclair ZX Spectrum cass. | Crosswize Model 011811 | 1988 | Firebird Soft. UK 012439 |
| Sinclair ZX Spectrum cass. | Crusader Model 1 STZ 501 | 1988 | SPE Spain |
| Sinclair ZX Spectrum cass. | Cup Football Model CF | 1988 | Cult |
| Sinclair ZX Spectrum cass. | Cyberknights | 1988 | CRL Group PLC London, England |
| Sinclair ZX Spectrum cass. | Cybernoid | 1988 | Erbe Soft. Spain |
| Sinclair ZX Spectrum cass. | Cybernoid - The Fighting Machine Model 010533 | 1988 | Hewson Consultants, Ltd. England 012635 |
| Sinclair ZX Spectrum cass. | Cybernoid II - The Revenge | 1988 | IBSA Spain |
| Sinclair ZX Spectrum cass. | Cybernoid II - The Revenge Model 010625 | 1988 | Hewson Consultants, Ltd. England 012635 |
| Sinclair ZX Spectrum cass. | Daley Thompson's Olympic Challenge Model 012549 | 1988 | Ocean Soft., Ltd. 13156 |
| Sinclair ZX Spectrum cass. | Dangerous Garden | 1988 | CV |
| Sinclair ZX Spectrum cass. | Dark Fusion Model 021247 | 1988 | Gremlin Graphics Soft., Ltd. 013658 |
| Sinclair ZX Spectrum cass. | Dark Side | 1988 | Incentive Soft., Ltd. |
| Sinclair ZX Spectrum cass. | Data East's Arcade Alley | 1988 | US Gold, Ltd. Birmingham, England 13442 |
| Sinclair ZX Spectrum cass. | Dea Tenebrarum Model 1SEA-308 | 1988 | System 4 de Espana, S.A. Spain |
| Sinclair ZX Spectrum cass. | Delfox Model SPE 880011 | 1988 | Dinamic Soft. Madrid, Spain |
| Sinclair ZX Spectrum cass. | Demon's Dream | 1988 | Redefine Keys |
| Sinclair ZX Spectrum cass. | Denizen | 1988 | Players Soft. |
| Sinclair ZX Spectrum cass. | Desolator | 1988 | US Gold, Ltd. Birmingham, England 13442 |
| Sinclair ZX Spectrum cass. | Desolator | 1988 | Erbe Soft. Spain |
