| Amstrad CPC cass. |  Aftermath Model AS217 | 1988 | Alternative Soft., Ltd. |
| Commodore C64 cass. | Aftermath Model AS265 | 1988 | Alternative Soft., Ltd. |
| Amstrad CPC cass. | Afteroids | 1988 | Zigurat Soft. Spain |
| MSX cass. | Afteroids | 1988 | Zigurat Soft. Spain |
| Amstrad CPC 464 disk | Afteroids | 1988 | Zigurat Soft. Spain |
| Sinclair ZX Spectrum cass. | Afteroids Model AFT2_SP | 1988 | Zigurat Soft. Spain |
| Hitachi MB-S1 type-in | Again - Onigo no Gyakushuu | 1988 | Dempa Shinbunsha Japan |
| NEC PC-8801 Series disk | Agni no Ishi - The Stone of Agni | 1988 | HummingBird Japan |
| Nintendo Famicom cart. | Ai no Densetsu - Olympus no Tatakai Model IMA-AD | 1988 | Imagineer Co., Ltd. Japan |
| Elektronika BK0010 cass. | Air battle | 1988 | Zotov AJ |
| Pachinko | Air Force | 1988 | Sanyo Japan |
| Pachinko | Air Shuttle | 1988 | Sanyo Japan |
| Atari XE cart. | Airball Model RX8109 | 1988 | Atari Corp. CA, USA |
| Amstrad CPC cass. | Airborne Ranger | 1988 | MicroProse, Ltd. Bristol, UK 015352 |
| Sinclair ZX Spectrum cass. | Airborne Ranger | 1988 | MicroProse, Ltd. Bristol, UK 015352 |
| Amstrad CPC 464 disk | Airborne Ranger | 1988 | MicroProse, Ltd. Bristol, UK 015352 |
| IBM PC 3.5in. disk | Airborne Ranger | 1988 | MicroProse, Ltd. Bristol, UK 015352 |
| Sinclair ZX Spectrum+3 disk | Airborne Ranger | 1988 | MicroProse, Ltd. Bristol, UK 015352 |
| Handheld game | Airwolf | 1988 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Sinclair ZX Spectrum cass. |  Airwolf | 1988 | Encore 012189 |
| Nintendo Famicom cart. | Airwolf Model KYG-AX | 1988 | Kyugo Japan |
| Sinclair ZX Spectrum cass. |  Airwolf Model LS-036 | 1988 | MCM Soft. Spain |
| MSX 2 disk | Akanbe Dragon | 1988 | Winky Soft. Japan |
| Nintendo Famicom disk | Akara Senki Raijin Model SQF-RJN | 1988 | Square Co., Ltd. Japan |
| MSX 2 type-in | Akazukin Oukami Taiji Densetsu | 1988 | Dempa Shinbunsha Japan |
| NEC PC-9801 Series 5.25in. disk | Aki to Tsukasa no Fushigi no Kabe | 1988 | System House Oh! Japan |
| Nintendo Famicom cart. | Akira Model TFC-AK-6800 | 1988 | Taito Corp. Japan |
| Arcade Video game | Akumajou Dracula Model GX768 | 1988 | Konami Industry Co., Ltd. Japan |
| NEC PC-8801 Series disk | Akuryou no Machi | 1988 | Unknown Japan |
| NEC PC-9801 Series 3.5in. disk | Alantia Model R-3543~45 | 1988 | Victor Musical Industries, Inc. Japan |
| NEC PC-9801 Series 5.25in. disk | Alantia Model R-5083~85 | 1988 | Victor Musical Industries, Inc. Japan |
| Arcade Video game |  Albatross | 1988 | Face Co., Ltd. Tokyo, Japan |
| Commodore Amiga 500 disk | Albedo | 1988 | Myriad |
| MSX cass. | Ale Hop! | 1988 | Topo Soft. Spain |
| Commodore Amiga 500 disk | Alert | 1988 | ECP Entertainment & Computer Products Pty. Ltd. |
| Sega Mark III cart. | Aleste Model G-1352 | 1988 | SEGA Enterprises, Ltd. Tokyo, Japan |
| MSX 2 cart. | Aleste Model IA-8801 | 1988 | Compile |
| Sega Master System cart. | Alex Kidd - The Lost Stars Model 7005 P | 1988 | Tonka Corp. MN, USA |
| Sega Master System cart. | Alex Kidd - The Lost Stars Model 7005 P | 1988 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mark III cart. | Alex Kidd - The Lost Stars Model G-1347 P | 1988 | SEGA Enterprises, Ltd. Tokyo, Japan |
