| Amstrad CPC 464 disk |  Databox 09-88 | 1988 | DMV Daten und Medien Verlag Eschwege, Germany |
| Amstrad CPC 464 disk | Databox 10-88 | 1988 | DMV Daten und Medien Verlag Eschwege, Germany |
| Amstrad CPC cass. | Databox 11-88 | 1988 | DMV Daten und Medien Verlag Eschwege, Germany |
| Amstrad CPC 464 disk | Databox 11-88 | 1988 | DMV Daten und Medien Verlag Eschwege, Germany |
| Amstrad CPC 464 disk | Databox 12-88 | 1988 | DMV Daten und Medien Verlag Eschwege, Germany |
| Amstrad CPC 464 disk | Databox Sonderheft 07-88 | 1988 | DMV Daten und Medien Verlag Eschwege, Germany |
| Apple II 5.25 disk | Dataquest Composer - North American Mammals Model MECC-A250 | 1988 | MECC Minnesota Educational Computing Corp. |
| NEC PC-8801 Series disk | Datenshi Kyouko - Part I 18 | 1988 | System House Oh! Japan |
| NEC PC-9801 Series 5.25in. disk | Datenshi Kyouko - Part I | 1988 | System House Oh! Japan |
| Arcade Video game | Datsugoku - Prisoners of War | 1988 | SNK Corp. Shin Nihon Kikaku Japan |
| Atari 400/800 cass. | Dawn Raider | 1988 | Atlantis Soft. |
| Atari 400/800 cass. | Daylight Robbery | 1988 | Atlantis Soft. |
| Sinclair ZX Spectrum cass. | Dea Tenebrarum Model 1SEA-308 | 1988 | System 4 de Espana, S.A. Spain |
| Arcade Video game |  Dead Angle | 1988 | Fabtek, Inc. Redmond, WA, USA |
| MSX type-in | Dead Heat | 1988 | Dempa Shinbunsha Japan |
| Amstrad CPC 464 disk | Dead or Alive + Microball Model AS088 | 1988 | System 4 de Espana, S.A. Spain |
| Acorn BBC/Electron cass. | Dead or Alive Model AS086 | 1988 | Alternative Soft., Ltd. |
| IBM PC DOS pack. | Deadly Maze Sw | 1988 | Software Concepts |
| Commodore C64 disk | Deadzone | 1988 | Markt & Technik |
| NEC PC-9801 Series 5.25in. disk | Death Bringer | 1988 | Telenet Japan |
| NEC PC-88 VA disk | Death Bringer | 1988 | Telenet Japan |
| NEC PC-9801 Series 3.5in. disk | Death Bringer | 1988 | Telenet Japan |
| Amstrad CPC cass. | Death Stalker Model 2122 | 1988 | Codemasters Soft. Co., Ltd., The 015026 |
| Apple II 5.25 disk | Death Sword | 1988 | Epyx, Inc. Redwood City, CA, USA |
| Commodore C64 disk | Death Sword | 1988 | Epyx, Inc. Redwood City, CA, USA |
| Amstrad CPC cass. | Death Wake Model 61731495 | 1988 | Zafiro Soft. Div. Spain |
| IBM PC DOS pack. | DeathRace Ver. 2 Sw | 1988 | Tesseract Soft. |
| Apple II 5.25 disk | Decisive Battles Of The American Civil War, Vol. II | 1988 | SSG Strategic Studies Group Pty., Ltd. Australia |
| Apple II 5.25 disk | Decisive Battles Of The American Civil War, Vol. III | 1988 | SSG Strategic Studies Group Pty., Ltd. Australia |
| MSX cart. | Deep Dungeon - Madou Senki | 1988 | ScapTrust Japan |
| MSX cart. | Deep Dungeon II - Yuushi no Monshou | 1988 | ScapTrust Japan |
| Nintendo Famicom cart. | Deep Dungeon III - Yuushi e no Tabi Model SQF-UT | 1988 | Square Co., Ltd. Japan |
| Commodore Amiga 500 disk | Def Con 5 | 1988 | MicroProse, Ltd. Bristol, UK 015352 |
| Atari 2600 cart. | Defender II Model CX26120 P | 1988 | Atari Corp. CA, USA |
| Nintendo NES cart. | Defender II Model NES-SB-USA | 1988 | HAL Laboratory, Inc. Japan |
| Thomson TO disk | Defi au Tarot | 1988 | Coktel Vision |
| Amstrad CPC 464 disk | Defi au Tarot | 1988 | Coktel Vision |
| Atari ST disk | Deflektor | 1988 | Gremlin Graphics Soft., Ltd. 013658 |
| Apple IIGS disk | Deja Vu - A Nightmare Comes True Model 110303 | 1988 | Mindscape, Inc. Northbrook, IL, USA 24294 |
| Nintendo Famicom cart. | Deja Vu - Akumu wa Hotouni Yatte Raita Model KSC-DG | 1988 | Kemco, Ltd. |
