| Casio FP-1100 cass. |  Cavit Hb | 2021 | Inufuto |
| Fujitsu FM-7 cass. | Cavit Hb | 2021 | Inufuto |
| Hitachi MB-6890 (BM-LIII) cass. | Cavit Hb | 2021 | Inufuto |
| Hitachi MB-6885 (BM-Jr.) cass. | Cavit Hb | 2021 | Inufuto |
| PC/MS-Windows pack. | Centipede - Recharged | 2021 | GOG sp. z o.o. |
| Online Slot | Charlie Chance | 2021 | Play'n GO |
| Online Slot | Charlie Chance and the Curse of Cleopatra | 2021 | Play'n GO |
| PC/MS-Windows pack. | Chasing Tails - A Promise in the Snow Model 1555110 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Chat Millions Model 1499900 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Chernobylite | 2021 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Chernobylite Enhanced Edition Model 1016800 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Chess Brain - Dark Troops Model 1524690 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Chibiclub TD Model 1670210 | 2021 | Steam Valve Corp. |
| Applied Technology Microbee disk | ChickenMan's Adventure's Disk #31 Hb | 2021 | ChickenMan |
| Applied Technology Microbee disk | ChickenMan's Adventure's Disk #32 Hb | 2021 | ChickenMan |
| Applied Technology Microbee disk | ChickenMan's Adventure's Disk #33 Hb | 2021 | ChickenMan |
| PC/MS-Windows pack. | Children of Morta - Complete Edition | 2021 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Children's Jigsaw Puzzles - Beautifully Illustrated Model 1634540 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Children's Jigsaw Puzzles Model 1503410 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Chill Corner Model 1749630 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Chorus | 2021 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Chr$(143) Model 1695620 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Christmas Celebration With Sakuya Izayoi Model 1835060 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Christmas Griddlers Journey To Santa Model 1545370 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Christmas Massacre | 2021 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Christmas Stories - Yulemen Collector's Edition Model 1832250 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Christmas Wonderland 12 Model 1816960 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Chronicle of Innsmouth - Mountains of Madness Model 962700 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Chronicles of Sarval - Bridges of Koni Model 1715470 | 2021 | Steam Valve Corp. |
| Arcade Video game | Chrono Circle | 2021 | Andamiro Co., Ltd. |
| PC/MS-Windows pack. | Chronobreach Ultra Model 1297800 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Chuckle Phrase Builder Model 1457490 | 2021 | Steam Valve Corp. |
| Arcade Video game | Chunithm New | 2021 | SEGA Corp. |
| Arcade Video game | Chunithm Paradise | 2021 | SEGA Corp. |
| Arcade Video game | Chunithm Paradise Plus | 2021 | SEGA Corp. |
| Arcade Video game | Chunithm Super Star Plus | 2021 | SEGA Corp. |
| PC/MS-Windows pack. | Chupacabras - Night Hunt Model 1706570 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. |  Church of Stratum Prologue Model 1677000 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Ciel Nosurge - Ushinawareta Hoshi E Sasagu Uta - DX Model 1477480 | 2021 | Steam Valve Corp. |
| PC/MS-Windows pack. | Cinderella Phenomenon - Evermore Model 1496180 | 2021 | Steam Valve Corp. |
