| Slot Machine |  Twin Dragon | 2010 | Cron Corp. Japan |
| Video Slot Machine | Twister | 2010 | BetStone Isle of Man, UK |
| Slot Machine | Two for the Money | 2010 | Bally Tech., Inc. |
| PC/MS-Windows pack. | Two Worlds Epic Edition | 2010 | GOG sp. z o.o. |
| Coin-op Misc. game | Typhoon | 2010 | Triotech Amusement |
| Sony PSN: Shodai PS Archives pack. |  Uchu Goshoden - Bakuretsu Akindo Model NPJI-????? | 2010 | Hamster Japan |
| Nintendo Wii disc | uDraw Pictionary | 2010 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo Wii disc | uDraw Studio | 2010 | T-HQ, Inc. Toy HeadQuarters |
| PC/MS-Windows pack. | UFO - Afterlight | 2010 | GOG sp. z o.o. |
| Redemption mechanical game | UFO Balance Catcher | 2010 | SEGA Corp. |
| Sony PSP UMD |  Ultimate Hits: Dissidia - Final Fantasy - Universal Tuning Model UCAS-40322 | 2010 | Sony Computer Ent., Inc. SCEI Japan |
| Sony PSP UMD | Ultimate Hits: Dissidia - Final Fantasy - Universal Tuning Model ULJM-05761 | 2010 | Square Enix Co., Ltd. Japan |
| Sony PSP UMD | Ultimate Hits: Dissidia - Final Fantasy Model UCKS-45160 | 2010 | Square Enix Co., Ltd. Japan |
| Sony PSP UMD | Ultimate Hits: Dissidia - Final Fantasy Model ULJM-05760 | 2010 | Square Enix Co., Ltd. Japan |
| Slot Machine | Ultimate X Poker | 2010 | IGT International Game Technologies Reno, NV, USA |
| Arcade Video game | Ultra Tekichu | 2010 | Techno-Top, Ltd. Japan |
| Arcade Video game | Ultra Tekichu Tsundere | 2010 | Techno-Top, Ltd. Japan |
| Sony PSN: Shodai PS Archives pack. | Umi no Nushi Tsuri - Takarajima ni Mukatte Model NPJI-????? | 2010 | Marvelous Ent., Inc. |
| Sony PSN: Shodai PS Archives pack. | Umi no Oh! Yah! Model NPJI-????? | 2010 | Marvelous Ent., Inc. |
| PC/MS-Windows CD | Umineko no Naku Koro ni Chiru Episode 7 - Requiem of the Golden Witch | 2010 | 07th Expansion |
| PC/MS-Windows CD | Umineko no Naku Koro ni Chiru Episode 8 - Twilight of the Golden Witch | 2010 | 07th Expansion |
| PC/MS-Windows CD | Umineko no Naku Koro ni Tsubasa | 2010 | 07th Expansion |
| Sony PlayStation 3 disc | Uncharted 2 - Among Thieves Model BCUS-98257 | 2010 | Sony Computer Ent. America SCEA CA, USA |
| Sony PSN: Shodai PS Archives pack. | Ungra Walker Model NPJI-????? | 2010 | Hamster Japan |
| Redemption mechanical game | Urikire Gomen! Drink Choice | 2010 | Hope Japan |
| PC/MS-Windows pack. | Uru - Complete Chronicles | 2010 | GOG sp. z o.o. |
| Sega Genesis cart. | Uwol - Quest for Money Hb | 2010 | Mojon Twins, The |
| Amstrad CPC 464 disk | Uwol 2 - Quest For Money Hb | 2010 | Mojon Twins, The |
| Belogic Uzebox ROM | Uze Feud Hb | 2010 | Belogic |
| Belogic Uzebox ROM | Uze Snakes Hb | 2010 | Belogic |
| Belogic Uzebox ROM | Uzebox Movie Player Hb | 2010 | Belogic |
| Slot Machine | Valiant Knight Super Multi-Pay | 2010 | WMS Gaming, Inc. Chicago, IL, USA |
| Slot Machine | Valley of the Scarab | 2010 | Atronic |
| PC/MS-Windows pack. | Vampire - The Masquerade - Redemption | 2010 | GOG sp. z o.o. |
| Slot Machine | Vampire and Beauty | 2010 | Aruze Gaming America, Inc. Las Vegas, NV, USA |
| Slot Machine | Vampire's Embrace G+ Deluxe | 2010 | WMS Gaming, Inc. Chicago, IL, USA |
| Slot Machine | Vamps | 2010 | IGT International Game Technologies Reno, NV, USA |
| Sony PlayStation 3 disc | Vancouver 2010 | 2010 | SEGA Europe Ltd. |
| Sony PlayStation 3 disc | Vanquish | 2010 | SEGA of America, Inc. San Francisco, CA, USA |
| Microsoft XBOX 360 disc | Vanquish | 2010 | SEGA of America, Inc. San Francisco, CA, USA |
