| Pachislot |  Slot Basilisk - Kouka Ninpouchou Hitomi Jutsu ver. | 2010 | Mizuho Corp. Universal Ent. Group Japan |
| Slot Machine | Slot Club Silver | 2010 | Octavian Italy srl Bussolengo, VR, Italy |
| Slot Machine | Slotto Double Gold | 2010 | AC Coin & Slot USA |
| Slot Machine | Snakes & Ladders | 2010 | Mazooma Interactive Games Novomatic Group |
| Nintendo NES cart. | Sneak'n Peek Model KHG-SP-GBL Hb | 2010 | RetroZone |
| Microsoft XBOX 360 disc | Sniper - Ghost Warrior | 2010 | City Interactive USA, Inc. |
| PC/MS-Windows CD | Sniper - Ghost Warrior | 2010 | City Interactive USA, Inc. |
| Redemption mechanical game | Sniper DX | 2010 | GFI Japan |
| PC/MS-Windows pack. | Sniper Elite - Berlin 1945 | 2010 | GOG sp. z o.o. |
| Sony PSP UMD | SNK Arcade Classics Vol.1 Model ULJS-00297 | 2010 | SNK Playmore Japan |
| Slot Machine | Snow Day! | 2010 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Soccer Mania | 2010 | ELSY Electro System Imola, BO, Italy |
| Sony PSN: Shodai PS Archives pack. |  Sogaku Toshi Osaka Model NPJI-????? | 2010 | GungHo Online Ent. |
| Belogic Uzebox ROM | Sokoban World Hb | 2010 | Belogic |
| Amstrad CPC 464 disk | Soleil Vert Hb | 2010 | Sucres en Morceaux, Les |
| Sony PlayStation 3 disc | Sonic & SEGA All-Stars Racing Model BLES-00750 | 2010 | SEGA Europe Ltd. |
| Microsoft XBOX 360 disc | Sonic - Free Riders | 2010 | SEGA of America, Inc. San Francisco, CA, USA |
| Arcade Video game | Sonic Blast Heroes | 2010 | Taito Corp. Japan |
| Nintendo DS cart. | Sonic Classic Collection Model TWL-VSOE-USA P | 2010 | SEGA Corp. |
| Nintendo DS cart. |  Sonic Classic Collection TWL-VSOV-AUS P | 2010 | SEGA Corp. |
| Nintendo DS cart. | Sonic Classic Collection TWL-VSOV-EUR P | 2010 | SEGA Corp. |
| Nintendo Wii disc | Sonic Colors | 2010 | SEGA Corp. |
| Sony PSN: PSone Classics pack. | Sorcerer's Maze Model NPEF-00103 | 2010 | XS Games |
| Sony PSN: PSone Classics pack. | Sorcerer's Maze Model NPUJ-01495 | 2010 | Console Classics |
| Sony PSN: PSone Classics pack. | Soviet Strike Model NPUJ-????? | 2010 | Electronic Arts CA, USA 14633 |
| Slot Machine | Space Ace | 2010 | Compu-Games A.S. Esbjerg, Denmark |
| Redemption mechanical game | Space Ballz | 2010 | JET Jennison Ent. Technologies Daytona Beach, FL, USA |
| Belogic Uzebox ROM | Space Invaders Hb | 2010 | Belogic |
| PC/MS-Windows pack. | Space Quest 1+2+3 | 2010 | GOG sp. z o.o. |
| PC/MS-Windows pack. | Space Quest 4+5+6 | 2010 | GOG sp. z o.o. |
| Slot Machine | Sparkling Diamonds Mega Series | 2010 | Bally Tech., Inc. |
| Slot Machine | Sparrow | 2010 | EVG spa Elettronica Video-Games Cormano, MI, Italy |
| Fruit Machine | Special Dice | 2010 | Barcrest Games |
| Arcade Video game | Speed Driver 3 - Crash Hour | 2010 | IGS Co., Ltd. International Game System |
| Slot Machine | Speed Racer | 2010 | Lightning Gaming, Inc. Boothwyn, PA, USA |
| PC/MS-Windows CD | SpellForce 2 - Faith in Destiny | 2010 | Nordic Games GmbH |
| Microsoft XBOX 360 disc | Spider-Man - Shattered Dimensions | 2010 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Sony PlayStation 3 disc | Spider-Man - Shattered Dimensions Model BLUS-30499 | 2010 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Medal video game | Spiral Dealer | 2010 | Taito Corp. Japan |
| Slot Machine | Spirit Bear | 2010 | IGT International Game Technologies Reno, NV, USA |
