| Slot Machine |  Romeo & Juliet | 2010 | IGT International Game Technologies Reno, NV, USA |
| Sony PlayStation 3 disc |  Rorona no Atelier - Arland no Renkinjutsushi Model BLJM-55018 | 2010 | Gust Japan |
| Slot Machine | Royal Diamonds Double Hit Game Plus | 2010 | Ainsworth Game Technology, Ltd. |
| Slot Machine | Royal Race Course | 2010 | AGT Advanced Games Technology Taiwan |
| Slot Machine | Royal Riverboat Run | 2010 | Atronic |
| Slot Machine | Royal Treasures Deluxe | 2010 | AGI Austrian Gaming Industries Novomatic Group |
| Belogic Uzebox ROM | Ruby Crush Hb | 2010 | Belogic |
| Slot Machine | Ruby Reels Spinning Reel | 2010 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Ruby Rush | 2010 | Bally Tech., Inc. |
| Slot Machine | Ruby Saloon | 2010 | Aristocrat Leisure Industries Pty, Ltd. |
| Sony PSN: Shodai PS Archives pack. | Rung Rung - Oz no Mahou Tsukai - Another World Model NPJJ-00442 | 2010 | GungHo Online Ent. |
| Slot Machine | Ruusu | 2010 | Ray Espoo, Finland |
| Sony PlayStation 3 disc | Ryu ga Gotoku 4 - Densetsu o Tsugumono Model BLJM-60208 | 2010 | SEGA Corp. |
| Arcade Video game | Sabin Sound Star | 2010 | 3S Ent. |
| Arcade Video game | Sabin Sound Star - Renascence Burst | 2010 | 3S Ent. |
| Sony PlayStation 3 disc | Sacred 2 - Fallen Angel Model BLJS-10071 | 2010 | Spike Japan |
| Slot Machine | Saguaro | 2010 | IGT International Game Technologies Reno, NV, USA |
| Sony PSN: Shodai PS Archives pack. | Saikyo Ginsei Chess Model NPJI-????? | 2010 | Hamster Japan |
| Sony PSN: Shodai PS Archives pack. | Saikyo Ginsei Mahjong Model NPJI-????? | 2010 | Hamster Japan |
| Sony PSN: Shodai PS Archives pack. | Saikyo Ginsei Shogi 2 Model NPJI-????? | 2010 | Hamster Japan |
| Slot Machine | Saiyuki | 2010 | AGT Advanced Games Technology Taiwan |
| Sony PSN: Shodai PS Archives pack. | Salaryman Champ - Tatakau Salaryman Model NPJI-????? | 2010 | Hamster Japan |
| Slot Machine | Samba Parade | 2010 | Orion Gaming |
| Arcade Video game | Sangokushi Taisen 3 - War Begins | 2010 | SEGA Corp. |
| Pachislot | SanSan Oasis 25-Pai | 2010 | Pioneer Co., Ltd. Japan |
| Slot Machine | Sapphire Sky | 2010 | Bally Tech., Inc. |
| Microsoft XBOX 360 disc | SBK X - Superbike World Championship | 2010 | Black Bean Games |
| PC/MS-Windows CD | SBK X - Superbike World Championship | 2010 | Black Bean Games |
| Sony PlayStation 3 disc | SBK X - Superbike World Championship Model BLES-00774 | 2010 | Black Bean Games |
| Fruit Machine | Scoobie | 2010 | Empire Games, Ltd. Bridgend, England |
| Redemption mechanical game | Sea Wolf - The Next Mission | 2010 | Coastal Amusements, Inc. Lakewood, NJ, USA |
| Slot Machine | Secret Mine | 2010 | Konami Gaming, Inc. Las Vegas, NV, USA |
| Slot Machine | Secrets of the Forest | 2010 | IGT International Game Technologies Reno, NV, USA |
| GCE Vectrex | Sectis Hb | 2010 | Fury Unlimited |
| Arcade Video game | Sega Card-Gen MLB 2010 | 2010 | SEGA Corp. |
| Arcade Video game | Sega Golden Gun | 2010 | SEGA Corp. |
| PC/MS-Windows CD | Sega Mega Drive Classics Collection Vol. 1 | 2010 | SEGA Europe Ltd. |
| PC/MS-Windows CD | Sega Mega Drive Classics Collection Vol. 2 | 2010 | SEGA Europe Ltd. |
| PC/MS-Windows CD | Sega Mega Drive Classics Collection Vol. 3 | 2010 | SEGA Europe Ltd. |
| Sony PSN: Shodai PS Archives pack. | Seiken Densetsu - Legend of Mana Model NPJI-????? | 2010 | Square Enix Co., Ltd. Japan |
