| Handheld game |  Les Envahisseurs | 1981 | Ludotronic France |
| Handheld game | Lightfight Model 4144 | 1981 | MB Milton Bradley Co. East Longmeadow, MA, USA |
| Handheld game | Lion Model LN-08 | 1981 | Nintendo Co., Ltd. Japan |
| Handheld game | Long Beach Grand Prix Model 40540 | 1981 | Kenner |
| Handheld game | Manhole Model MH-06 | 1981 | Nintendo Co., Ltd. Japan |
| Handheld game | Memory Match Model 60-2122 | 1981 | Tandy Corp. |
| Handheld game | Mickey Mouse Model MC-25 | 1981 | Nintendo Co., Ltd. Japan |
| Handheld game | Mini Sensory Chess Challenger | 1981 | Fidelity Electronics |
| Handheld game | Monkey | 1981 | VTECH Video Technology, Ltd. |
| Handheld game | Monkey Business Model 8108 | 1981 | Bandai Co., Ltd. Japan |
| Handheld game | Monster Panic Model 36520 | 1981 | Epoch Co., Ltd. Tokyo, Japan |
| Handheld game | Octopus Model OC-22 | 1981 | Nintendo Co., Ltd. Japan |
| Handheld game | Oil Gang | 1981 | Epoch Co., Ltd. Tokyo, Japan |
| Handheld game | Ottosei Land Model 16197 | 1981 | Bandai Co., Ltd. Japan |
| Handheld game | Pac Man 2 | 1981 | Entex Industries, Inc. Compton, CA, USA |
| Handheld game | Pak-Pak Man | 1981 | Unimex |
| Handheld game | Pancake | 1981 | VTECH Video Technology, Ltd. |
| Handheld game | Parachute Model PR-21 | 1981 | Nintendo Co., Ltd. Japan |
| Handheld game | Pinball | 1981 | Gakken Japan |
| Handheld game | Pirate | 1981 | Acetronic |
| Handheld game | Pocket Repeat Model 60-2152 | 1981 | Tandy Corp. |
| Handheld game | Popeye Model PP-23 | 1981 | Nintendo Co., Ltd. Japan |
| Handheld game | Programmable Baseball | 1981 | US Games Corp. Santa Clara, CA, USA |
| Handheld game | Red Line | 1981 | Kenner |
| Handheld game | Reflex Model 4000 | 1981 | Parker Bros. Beverly, MA, USA |
| Handheld game | Rocket Pinball Model 60-2140 | 1981 | Tandy Corp. |
| Handheld game | Rushhour Model 16263 | 1981 | Bandai Co., Ltd. Japan |
| Handheld game | Safari | 1981 | Acetronic |
| Handheld game | Savant | 1981 | NOVAG |
| Handheld game | Sleep Walker | 1981 | VTECH Video Technology, Ltd. |
| Handheld game | Slimboy Shooting 6 | 1981 | Tomy |
| Handheld game | Slimline Speedway Model 7605 | 1981 | Tomy |
| Handheld game | Soccer 2 Model HG-821 | 1981 | Tommy |
| Handheld game | Sonic Invader | 1981 | VTECH Video Technology, Ltd. |
| Handheld game | Space Invader Model COP444 | 1981 | Entex Industries, Inc. Compton, CA, USA |
| Handheld game | Speak & Spell Compact | 1981 | Texas Instruments |
| Handheld game | Sports Arena Model 60-2158 | 1981 | Tandy Corp. |
| Handheld game | Star Hawk Model 5152 | 1981 | Mattel Electronics Mattel, Inc. |
| Handheld game | Sub Wars Model 7-490 | 1981 | Tiger Electronic Toys, Inc. Orchard Mundelein, IL, USA |
| Handheld game | Super Battles | 1981 | Gakken Japan |
