| Handheld game |  Popeye Model PP-23 | 1981 | Nintendo Co., Ltd. Japan |
| Commodore VIC-20 type-in | Pot Shot | 1981 | EMAP East Midlands Allied Press |
| Commodore VIC-20 type-in | Potshot | 1981 | EMAP East Midlands Allied Press |
| Apple II 5.25 disk | President Elect | 1981 | SSI Strategic Simulations, Inc. 16685 |
| TRS-80 type-in | Press-Ups | 1981 | SoftSide Publications, Inc. |
| TRS-80 cass. | Pro-Pix '81 Model 010-0019 | 1981 | Adventure International |
| TRS-80 disk | Pro-Pix '81 Model 012-0019 | 1981 | Adventure International |
| Pinball | Professional Pinball | 1981 | Geiger-Automatenbau |
| Sinclair ZX-81 cass. | Program Pack 4 | 1981 | Bug-Byte London, England |
| Handheld game | Programmable Baseball | 1981 | US Games Corp. Santa Clara, CA, USA |
| TRS-80 CoCo cart. | Project Nebula | 1981 | Tandy Corp. |
| TRS-80 disk | Project Nebula Model 26-3063 | 1981 | Tandy Corp. |
| TRS-80 cass. | Project Omega Model 010-0076 | 1981 | Adventure International |
| TRS-80 disk | Project Omega Model 012-0076 | 1981 | Adventure International |
| Atari 400/800 disk | Protector | 1981 | Synapse Soft. Corp. |
| Atari 400/800 disk | Protector | 1981 | Crystalware |
| NEC PC-8001 disk | Puck Man | 1981 | Compaq |
| Apple II cass. | Puck Man | 1981 | Star Craft |
| Sinclair ZX-81 cass. | Puckman | 1981 | Hewson Consultants, Ltd. England 012635 |
| Sharp MZ-80B type-in | Puckman P | 1981 | Kohgaku-Sha Co.,Ltd. |
| Apple II 5.25 disk | Pulsar II | 1981 | Sirius Soft., Inc. Sacramento, CA, USA |
| Arcade Video game | Pulsar Model 734-0039 | 1981 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Arcade Video game | Punching Kid | 1981 | Irem Corp. Japan |
| Video Slot Machine | Push Over | 1981 | Summit Coin |
| TRS-80 cass. | Pyramid 2000 Model 26-1909 | 1981 | Radio Shack Fort Worth, TX, USA |
| Texas instrument TI-99/4A cass. | Pyramid of Doom Model PHT 6052 | 1981 | Texas Instruments |
| Arcade Video game | Qix | 1981 | Taito Corp. Japan |
| Video Slot Machine | Quarter Horse Model ??? | 1981 | ESI Electro Sport, Inc. Costa Mesa, CA, USA |
| Apple II type-in | Quest 1 P | 1981 | SoftSide Publications, Inc. |
| Atari 400/800 type-in | Quest 1 P | 1981 | SoftSide Publications, Inc. |
| TRS-80 type-in | Quest 1 | 1981 | SoftSide Publications, Inc. |
| Atari 400/800 disk | Quest for Power | 1981 | Crystalware |
| Phillips Videopac cart. | Quest for the Rings Model 42 | 1981 | Philips Corp. |
| Magnavox Odyssey² cart. | Quest for the Rings Model AC9429 | 1981 | Magnavox Co., The Fort Wayne, IN, USA |
| Atari 400/800 disk | Questions et Réponses Model APX 20081 D | 1981 | Atari PECF Creteil, France |
| Tabletop game | Quiz Wiz Challenger Model 2100 | 1981 | Coleco Industries, Inc. Amsterdam, NY, USA |
| Arcade Video game |  Quizimodo | 1981 | Gottlieb & Co., D. Chicago, IL, USA |
| Arcadia 2001 cart. | R2D Tank | 1981 | UA, Ltd. USA |
| TRS-80 cass. | Raaka-Tu Model 26-1915 | 1981 | Radio Shack Fort Worth, TX, USA |
| Tabletop game | Race 'N' Chase Model ET-0701 | 1981 | Bambino, Inc. Los Angeles, CA, USA |
