| Apple II 5.25 disk |  Dunjonquest: Sorcerer of Siva | 1981 | Automated Simulations, Inc. |
| TRS-80 cass. | Dunjonquest: Sorcerer of Siva Model 342C | 1981 | Automated Simulations, Inc. |
| Atari 400/800 cass. | Dunjonquest: The Datestones of Ryn | 1981 | Automated Simulations, Inc. |
| Atari 400/800 disk | Dunjonquest: The Datestones of Ryn | 1981 | Automated Simulations, Inc. |
| Apple II/TRS-80 disk | Dunjonquest: The Datestones of Ryn | 1981 | Automated Simulations, Inc. |
| Arcade Video game | Dwarfs Den 13in. Upright model | 1981 | ESI Electro Sport, Inc. Costa Mesa, CA, USA |
| Arcade Video game | Dwarfs Den 19in. Upright model | 1981 | ESI Electro Sport, Inc. Costa Mesa, CA, USA |
| Arcade Video game | Dwarfs Den Cocktail model | 1981 | ESI Electro Sport, Inc. Costa Mesa, CA, USA |
| Arcade Video game | Dwarfs Den Countertop model | 1981 | ESI Electro Sport, Inc. Costa Mesa, CA, USA |
| Sharp MZ-80K type-in | Earth Trek | 1981 | ASCII Corp. Japan |
| Pinball | Earth Wind & Fire | 1981 | Zaccaria Bologna, Italy |
| Atari 400/800 disk | Eastern Front 1941 | 1981 | APX Atari Program Exchange |
| Handheld game | Egg Model EG-26 | 1981 | Nintendo Co., Ltd. Japan |
| Pinball | Eight Ball Deluxe Model 1220 | 1981 | Bally Mfg. Co. Chicago, IL, USA |
| PTC SOL-20 cass. | Eight Men P | 1981 | Hopkins, Ralph |
| Nascom cass. | Eldorado Gold | 1981 | Program Power |
| Phillips Videopac cart. | Electronic Billiards Model 35 | 1981 | Philips Corp. |
| Handheld game | Electronic Chess | 1981 | Tryom, Inc. OH, USA |
| Phillips Videopac cart. | Electronic Ice Hockey + Electronic Soccer Model 36 | 1981 | Philips Corp. |
| Handheld game | Electronic Shooting Gallery Model 60-2155 | 1981 | Tandy Corp. |
| Pinball | Elektra Model 1248 | 1981 | Bally Mfg. Co. Chicago, IL, USA |
| Apple II 5.25 disk | Elementary Vol. 6 Model MECC-A725 | 1981 | MECC Minnesota Educational Computing Corp. |
| Apple II 5.25 disk | Elementary Vol. 7 Model MECC-A731 | 1981 | MECC Minnesota Educational Computing Corp. |
| Apple II 5.25 disk | Eliminator | 1981 | Anderson, John |
| Arcade Video game | Eliminator 4-Player model | 1981 | Gremlin Ind, Inc. San Diego, CA, USA |
| Arcade Video game | Eliminator Cocktail 2-Player model | 1981 | Gremlin Ind, Inc. San Diego, CA, USA |
| TRS-80 cass. | Eliminator Model 010-0134 | 1981 | Adventure International |
| TRS-80 disk | Eliminator Model 012-0134 | 1981 | Adventure International |
| Apple II 5.25 disk | Eliminator Model 042-0134 | 1981 | Adventure International |
| Arcade Video game | Eliminator Upright 2-Player model | 1981 | Gremlin Ind, Inc. San Diego, CA, USA |
| Chess board | Elite Champion Challenger | 1981 | Fidelity Electronics |
| Osborne-1 disk | Eliza | 1981 | Software Toolworks, The |
| Heath/Zenith H8 soft. | Eliza P | 1981 | Creative Computing Soft. |
| CP/M 8in. disk | Eliza P | 1981 | Software Toolworks, The |
| Pinball | Embryon Model 1222 | 1981 | Bally Mfg. Co. Chicago, IL, USA |
| Atari 800/Apple II/TRS-80 cass. | Empire of the Overmind Model 41101 | 1981 | Microcomputer Games |
| TRS-80 disk | Empire of the Overmind Model 41151 | 1981 | Microcomputer Games |
| Apple II 5.25 disk | Empire of the Overmind Model 41152 | 1981 | Microcomputer Games |
| Atari 400/800 disk | Empire of the Overmind Model 41153 | 1981 | Microcomputer Games |
| Atari 400/800 cass. | Encounter at Questar IV | 1981 | Artworx Soft. Co., Inc. |
