| TRS-80 cass. |  Zossed in Space Model 010-0049 | 1980 | Adventure International |
| Amstrad CPC/PCW disk | CPM 03 | 1980 | Adventure PD London, England |
| TRS-80 disk | Cosmic Intruders | 1980 | Ala Video |
| Arcade Video game | Shougi | 1980 | Alpha Denshi Co., Ltd. Japan |
| TRS-80 disk | Wizard's Castle | 1980 | Alternate Source, The |
| Handheld game | Football Model 2026 | 1980 | Amico Electronics |
| Arcade Video game | Phoenix | 1980 | Amstar Electronics Corp. Phoenix, AZ, USA |
| Bally Astrocade type-in | Chessette | 1980 | Anderson, Craig |
| Apple II 5.25 disk | Adventure | 1980 | Apple Computer, Inc. |
| Apple II 5.25 disk | Apple Stellar Invaders | 1980 | Apple Computer, Inc. |
| Apple II 5.25 disk | Bridge Tutor with Precision and Scientific Bidding | 1980 | Apple Computer, Inc. |
| Apple II 5.25 disk | Galactic Wars | 1980 | Apple Computer, Inc. |
| Applied Concepts Great Game Machine mod. | Boris 2.5 / Sargon 2.5 | 1980 | Applied Concepts, Inc. |
| Chess board | Great Game Machine | 1980 | Applied Concepts, Inc. |
| Applied Concepts Great Game Machine mod. | Las Vegas 21 - Master Blackjack | 1980 | Applied Concepts, Inc. |
| Signetics 2650 cass. | Games Tape 1 | 1980 | Applied Technology Pty., Ltd. |
| Signetics 2650 cass. | Games Tape 2 | 1980 | Applied Technology Pty., Ltd. |
| Signetics 2650 cass. | Games Tape 3 | 1980 | Applied Technology Pty., Ltd. |
| TRS-80 cass. | Games Tape T1 | 1980 | Applied Technology Pty., Ltd. |
| TRS-80 cass. | Games Tape T2 | 1980 | Applied Technology Pty., Ltd. |
| Signetics 2650 cass. | Microworld Sargon Chess | 1980 | Applied Technology Pty., Ltd. |
| Applied Technology Microbee cass. | Target | 1980 | Applied Technology Pty., Ltd. |
| Apple II 5.25 disk | Dungeon of Doom | 1980 | Argon Games |
| Pinball | Sexy Girl | 1980 | Arkon Automaten |
| Atari 400/800 cass. | Hearts 1.5 | 1980 | Artworx Soft. Co., Inc. |
| RCA COSMAC VIP type-in | Flip/Flop | 1980 | Association of Computer Experimenters |
| RCA COSMAC VIP type-in | Life for 1802! P | 1980 | Association of Computer Experimenters |
| RCA COSMAC VIP type-in | Ortho | 1980 | Association of Computer Experimenters |
| RCA COSMAC VIP type-in | Russian Roulette | 1980 | Association of Computer Experimenters |
| RCA COSMAC VIP type-in | Tic-Tac-Toe Modification | 1980 | Association of Computer Experimenters |
| Apple II cass. | The Bomber | 1980 | Astar International, Inc. |
| Atari 400/800 cass. | Ministre de l'Energie Model CX 4121 | 1980 | Atari PECF Creteil, France |
| Atari 2600 cart. |  3-D Tic-Tac-Toe Model CX2618P | 1980 | Atari, Inc. CA, USA |
| Arcade Video game | Asteroids Cabaret model | 1980 | Atari, Inc. CA, USA |
| Arcade Video game | Asteroids Cocktail model | 1980 | Atari, Inc. CA, USA |
| Arcade Video game | Atari Soccer | 1980 | Atari, Inc. CA, USA |
| Arcade Video game | Battlezone Cabaret model | 1980 | Atari, Inc. CA, USA |
| Arcade Video game | Battlezone Upright model | 1980 | Atari, Inc. CA, USA |
| Atari 400/800 cass. | Biorhythm | 1980 | Atari, Inc. CA, USA |
| Atari 400/800 cass. | Blackjack | 1980 | Atari, Inc. CA, USA |
