| Bally Astrocade type-in |  Crazy Ball | 1980 | L&M Soft. Newburgh, IN, USA |
| Arcade Video game | Crazy Balloon | 1980 | Taito Corp. Japan |
| Sharp MZ-80K type-in | Crazy Balloon P | 1980 | Kohgaku-Sha Co.,Ltd. |
| Arcade Video game |  Crazy Climber | 1980 | Model Racing S.p.a. Montemarciano, Italy |
| Arcade Video game | Crazy Climber | 1980 | Operamatic Spain |
| Arcade Video game | Crazy Climber | 1980 | Rodmar Elec. Spain |
| Arcade Video game | Crazy Climber Model CC-70001 | 1980 | Nichibutsu Nihon Bussan Co., Ltd. Osaka, Japan |
| Arcade Video game | Crazy Climber Model CCA-7001 | 1980 | Nichibutsu Nihon Bussan Co., Ltd. Osaka, Japan |
| Bally Astrocade type-in | Crazy Face | 1980 | Walters, S.L. |
| Atari 400/800 cass. | Cribbage Model CS-7008 | 1980 | Creative Computing Soft. |
| Bally Astrocade cass. | Critter | 1980 | Bilbrey, Brett |
| Apple II 5.25 disk | Crossword | 1980 | Softape |
| Apple II 5.25 disk | Crossword Magic | 1980 | Computerware |
| Apple II 5.25 disk | Cyber Strike | 1980 | Sirius Soft., Inc. Sacramento, CA, USA |
| Handheld game | Cylon 16 | 1980 | Yonezawa Corp. Japan |
| Sharp MZ-80K type-in | D-Day | 1980 | Kohgaku-Sha Co.,Ltd. |
| Sharp MZ-80K cass. | D-Day Model Z-1045 | 1980 | Hudson Soft. Hudson Group Japan |
| Phillips Videopac cart. | Dam Buster Model 29 | 1980 | Philips Corp. |
| TRS-80 cass. | Dancing Demon Model 26-1911 | 1980 | Radio Shack Fort Worth, TX, USA |
| Arcade Video game | Dancing Queen | 1980 | Denki Onkyo |
| TRS-80 type-in | Dante's Inferno | 1980 | SoftSide Publications, Inc. |
| Apple II cass. | Dart Room Model Ap133 | 1980 | Programma International, Inc. |
| Arcade Video game | DCA | 1980 | Karateco Tokyo, Japan |
| Slot Machine | Dead Heat | 1980 | Nichibutsu Nihon Bussan Co., Ltd. Osaka, Japan |
| TRS-80 type-in | Deadstick - Land the Space Shuttle | 1980 | SoftSide Publications, Inc. |
| TRS-80 disk | Death Dreadnaught | 1980 | Programmer's Guild, The |
| TRS-80 cass. | Death Dreadnaught | 1980 | Programmer's Guild, The |
| TRS-80 cass. | Death Trap | 1980 | Dick Smith Electronics |
| Apple II 5.25 disk | Deathmaze 5000 | 1980 | Med Systems |
| TRS-80 cass. | Deathmaze 5000 | 1980 | Med Systems |
| Sharp MZ-80K type-in | Deep Scan | 1980 | Kohgaku-Sha Co.,Ltd. |
| TRS-80 type-in | Deep Six | 1980 | SoftSide Publications, Inc. |
| Arcade Video game | Defender | 1980 | Williams Electronics, Inc. Chicago, IL, USA |
| Atari 400/800 disk | Deflection Model 051-0031 | 1980 | Adventure International |
| Handheld game | Deluxe Football Model 7-550 | 1980 | Tiger Electronic Toys, Inc. Orchard Mundelein, IL, USA |
| Acorn Atom cass. | Demon Dungeon | 1980 | Program Power |
| Pinball | Dennis Lillee's Howzat! | 1980 | Hankin & Co., A. Newcastle, Australia |
| Sharp MZ-80K type-in | Dentakumodoki | 1980 | Kosaido Publishing |
| Phillips Videopac cart. | Depth Charge + Marksman Model 16 | 1980 | Philips Corp. |
| Sharp MZ-80K cass. | Derby Model Z-1041 | 1980 | Hudson Soft. Hudson Group Japan |
