| Slot Machine |  Token Vender South Civil War Soldier | 1980 | Royal Casino Antiques |
| Arcade Video game | Tomahawk 777 | 1980 | Data East Corp. Japan |
| Arcade Video game | Tora Tora | 1980 | GPi Game Plan, Inc. IL, USA |
| Pinball | Torch Model 438 | 1980 | Gottlieb & Co., D. Chicago, IL, USA |
| Handheld game | Torpedo Shoot Model 8004 | 1980 | Bandai Co., Ltd. Japan |
| Handheld game | Toss-Up Model 72157 | 1980 | Mego Corp. |
| Coin-op Misc. game | Touch! Action | 1980 | Komaya Co., Ltd. Japan |
| Arcade Video game | Tranquillizer Gun | 1980 | SEGA Enterprises, Ltd. Tokyo, Japan |
| TRS-80 CMD file | Trap ver.1.0 | 1980 | Gray Soft. |
| TRS-80 cass. | Treasure Quest Model 010-0050 | 1980 | Adventure International |
| TRS-80 disk | Treasure Quest Model 012-0050 | 1980 | Adventure International |
| Atari 400/800 type-in | Trench | 1980 | SoftSide Publications, Inc. |
| Arcade Video game | Tri-Attacker | 1980 | Taito Corp. Japan |
| Arcade Video game | Tri-Attacker Cocktail model | 1980 | Taito Corp. Japan |
| Atari 400/800 disk | Trivia Unlimited Model CS-7501 | 1980 | Creative Computing Soft. |
| TRS-80 disk | TRS-80 Opera Model 011-0044 | 1980 | Adventure International |
| TRS-80 disk | Tunnels of Fahad Model 012-0019 | 1980 | Adventure International |
| Dedicated Console | TV Vader | 1980 | Epoch Co., Ltd. Tokyo, Japan |
| Mattel Intellivision cart. | U.S. Ski Team Skiing Model 1817 | 1980 | Mattel Electronics Mattel, Inc. |
| Arcade Video game | UFO | 1980 | Model Racing S.p.a. Montemarciano, Italy |
| Arcade Video game |  UFO | 1980 | Video Games, Ltd. Nottingham, England |
| Handheld game | UFO Attack | 1980 | Tomy |
| Apple II 5.25 disk | Ultima I | 1980 | California Pacific Computer |
| Arcade Video game |  Ultra Invaders | 1980 | Konami Industry Co., Ltd. Japan |
| Handheld game | Ultra Quiz Machine | 1980 | Tsukuda Original Japan |
| Bowler | United's Omni | 1980 | Williams Mfg. Co. Chicago, IL, USA |
| Arcade Video game | UniWar S | 1980 | Irem Corp. Japan |
| Video Slot Machine | Unknown 1980 poker game | 1980 | Unknown |
| Fruit Machine | Upstairs 'N' Downstairs | 1980 | Bell-Fruit Mfg. Co., Ltd. B.F.M. UK |
| Commodore PET cass. | Usage - Exercise Thirteen | 1980 | Micro-Ed, Inc. |
| Commodore PET disk | Valdez P | 1980 | DynaComp, Inc. |
| Apple II 5.25 disk | Valdez P | 1980 | DynaComp, Inc. |
| CP/M 8in. disk | Valdez P | 1980 | DynaComp, Inc. |
| Texas instrument TI-99/4A cart. | VAT Accounting Model PHM 3066 | 1980 | Texas Instruments |
| Commodore PET cass. | Verbs 1 | 1980 | Activity Records, Inc. |
| Commodore PET cass. | Verbs 2 | 1980 | Activity Records, Inc. |
| Commodore PET cass. | Verbs 3 | 1980 | Activity Records, Inc. |
| Commodore PET cass. | Verbs 4 | 1980 | Activity Records, Inc. |
| Handheld game | Vermin Model MT-03 | 1980 | Nintendo Co., Ltd. Japan |
| Arcade Video game | Video 21 | 1980 | Video Games, GmbH Lich, Germany |
