| RCA COSMAC ELF type-in |  Stix | 1980 | Quest Electronics |
| Exidy Sorcerer cass. | Stomper | 1980 | Unknown |
| Commodore PET cass. | Story Problems in Addition Subtraction | 1980 | Micro-Ed, Inc. |
| TRS-80 cass. | Strategy Games Model CS-3005 | 1980 | Creative Computing Soft. |
| Atari 400/800 type-in | Stratoblaster Outpost | 1980 | SoftSide Publications, Inc. |
| Arcade Video game |  Stratovox | 1980 | Taito Corp. Japan |
| TRS-80 type-in | Stud Poker | 1980 | SoftSide Publications, Inc. |
| Atari 2600 cart. |  Stunt Cycle | 1980 | Atari, Inc. CA, USA |
| Bally Astrocade type-in | Sub Search | 1980 | Fabris, Robert San Jose, CA, USA |
| Handheld game | Sumou Model 16181 | 1980 | Bandai Co., Ltd. Japan |
| Bowler | Super Ball | 1980 | FAB Electronics Co., Inc. |
| Atari 400/800 type-in | Super Barricade | 1980 | SoftSide Publications, Inc. |
| Handheld game | Super Breakout | 1980 | Atari, Inc. CA, USA |
| Sharp MZ-80K type-in | Super Commander | 1980 | Kohgaku-Sha Co.,Ltd. |
| Video Slot Machine | Super Conti | 1980 | SNK Corp. Shin Nihon Kikaku Japan |
| Bally Astrocade cass. | Super Craps | 1980 | Super Soft. |
| Video Slot Machine | Super Five | 1980 | SNK Corp. Shin Nihon Kikaku Japan |
| Handheld game | Super Galaxy Invader Model 8003 | 1980 | Bandai Co., Ltd. Japan |
| Apple II 5.25 disk | Super Galaxy Wars | 1980 | Broderbund Soft., Inc. CA, USA 47956 |
| Arcade Video game | Super GX | 1980 | Nichibutsu Nihon Bussan Co., Ltd. Osaka, Japan |
| Radofin 1292 Advanced Programmable Video System cart. | Super Knockout | 1980 | Radofin Electronics Germany |
| Arcade Video game | Super Man | 1980 | Shoei Co., Ltd. |
| Arcade Video game |  Super Meteor Cocktail model | 1980 | Hoei International, Inc. Japan |
| Arcade Video game | Super Meteor Upright model | 1980 | Hoei International, Inc. Japan |
| Arcade Video game | Super Moon Base | 1980 | Nichibutsu Nihon Bussan Co., Ltd. Osaka, Japan |
| TRS-80 cass. | Super Nova | 1980 | Big Five Soft. Van Nuys, CA, USA |
| Arcade Video game | Super Space Guerrilla | 1980 | OEC Omori Electric Co., Ltd. Japan |
| Arcade Video game | Super Speed Race GP V | 1980 | Taito Corp. Japan |
| Sharp MZ-80K type-in | Super Star Trek | 1980 | ASCII Corp. Japan |
| Bingo | Super Win | 1980 | Playmatic, S.A. Spain |
| Apple II 5.25 disk | SuperCube | 1980 | Software Alternatives |
| Commodore PET cass. | Synonym Game | 1980 | Micro-Ed, Inc. |
| Commodore PET cass. | Synonyms | 1980 | Microcomputers in Education |
| Commodore PET cass. | Synonyms 1 | 1980 | Activity Records, Inc. |
| Commodore PET cass. | Synonyms 2 | 1980 | Activity Records, Inc. |
| Commodore PET cass. | Synonyms 3 | 1980 | Activity Records, Inc. |
| Commodore PET cass. | Synonyms 4 | 1980 | Activity Records, Inc. |
| Arcade Video game | T.T Balloon Bomber | 1980 | Taito Corp. Japan |
| Arcade Video game | T.T Crazy Balloon | 1980 | Taito Corp. Japan |
| Arcade Video game | T.T Lupin III | 1980 | Taito Corp. Japan |
