| TRS-80 cass. |  Spider Mountain Adventure | 1980 | Programmer's Guild, The |
| TRS-80 disk | Spider Mountain Adventure | 1980 | Programmer's Guild, The |
| Apple II cass. | Spider Tag | 1980 | Programma International, Inc. |
| Handheld game | Split Second | 1980 | Miro-Meccano France |
| Handheld game | Split Second Model 3700 | 1980 | Parker Bros. Beverly, MA, USA |
| Handheld game | Sports Center Model 2009 | 1980 | House of Games, Inc. Waddingtons Evanston, IL, USA |
| HP-83/85 disk | Standard Pac Model 00085-13001 | 1980 | Hewlett-Packard |
| Arcade Video game | Star Castle | 1980 | Cinematronics, Inc. El Cajon, CA, USA |
| Arcade Video game |  Star Crest | 1980 | Taito do Brazil |
| Apple II 5.25 disk | Star Cruiser | 1980 | Sirius Soft., Inc. Sacramento, CA, USA |
| Bally Astrocade cass. | Star Fire | 1980 | Sebree's Computing |
| NEC PC-8001 disk | Star Fire!!! | 1980 | Ogi, Y. |
| Pinball | Star Gazer | 1980 | Stern Electronics, Inc. Elk Grove Village, IL, USA |
| Pinball | Star God | 1980 | Zaccaria Bologna, Italy |
| Arcade Video game | Star Invaders | 1980 | Potomac Mortgage Co. |
| Pinball | Star Race Model 657 | 1980 | Gottlieb & Co., D. Chicago, IL, USA |
| TRS-80 cass. | Star Trader Orion | 1980 | Automated Simulations, Inc. |
| TRS-80 disk | Star Trader Orion | 1980 | Automated Simulations, Inc. |
| Commodore PET cass. | Star Trader Orion | 1980 | Automated Simulations, Inc. |
| Apple II cass. | Star Trader Orion | 1980 | Automated Simulations, Inc. |
| Apple II 5.25 disk | Star Trader Orion | 1980 | Automated Simulations, Inc. |
| Compucolor II disk | Star Trek | 1980 | Epps, Graham |
| TRS-80 cass. | Star Trek + Star Wars | 1980 | Rainbow Computing, Inc. |
| TRS-80 cass. | Star Trek 3.5 Model 010-0025 | 1980 | Adventure International |
| TRS-80 disk | Star Trek 3.5 Model 012-0025 | 1980 | Adventure International |
| TRS-80 cass. | Star Trek III.5 | 1980 | Ramware |
| Apple II cass. | Star Warriors + Space Maze | 1980 | Softape |
| Sharp MZ-80K type-in | Star Wars | 1980 | Kohgaku-Sha Co.,Ltd. |
| Apple II cass. | Starquest: Rescue at Rigel | 1980 | Automated Simulations, Inc. |
| Atari 400/800 disk | Starquest: Rescue at Rigel | 1980 | Automated Simulations, Inc. |
| Apple II/TRS-80 disk | Starquest: Rescue at Rigel | 1980 | Automated Simulations, Inc. |
| Bally Astrocade cass. | Starship Bally | 1980 | Super Soft. |
| TRS-80 type-in | Startrek - Encounter in the near Thloian Secto ver. 2.0 | 1980 | SoftSide Publications, Inc. |
| TRS-80 type-in | Startrek III.4 | 1980 | SoftSide Publications, Inc. |
| TRS-80 type-in | States & Capitals | 1980 | SoftSide Publications, Inc. |
| Atari 400/800 type-in | States & Capitals | 1980 | SoftSide Publications, Inc. |
| Texas instrument TI-99/4A cart. | Statistik Model PHM 3014 | 1980 | Texas Instruments |
| Arcade Video game | Steel Worker | 1980 | Taito Corp. Japan |
| Pinball | Stellar Airship | 1980 | Geiger-Automatenbau |
| Atari 2600 cart. | Stellar Track Model 49-75159 | 1980 | Sears Chicago, IL, USA |
