| Bally Astrocade type-in |  Airbrush and Sandblast | 1980 | Fabris, Robert San Jose, CA, USA |
| Sharp MZ-80K type-in | Aishou Game | 1980 | Kosaido Publishing |
| Apple II 5.25 disk |  Akalabeth + Both Barrels - Retailer Demo | 1980 | California Computer Systems |
| Apple II 5.25 disk | Akalabeth - World of Doom | 1980 | California Pacific Computer |
| Apple II 5.25 disk | Akalabeth - World of Doom Hb | 1980 | Garriott, Richard |
| Sharp MZ-80K type-in | Aldebaran Part 1 | 1980 | Dempa Shinbunsha Japan |
| Sharp MZ-80K cass. | Aldebaran Part 1 Model Z-1046 | 1980 | Hudson Soft. Hudson Group Japan |
| Pinball | Algar | 1980 | Williams Electronics, Inc. Chicago, IL, USA |
| Pinball | Ali | 1980 | Stern Electronics, Inc. Elk Grove Village, IL, USA |
| Handheld game | Alien Avenger Model F-0095 | 1980 | Shinsei |
| NEC PC-8001 type-in | Alien Fall | 1980 | Kohgaku-Sha Co.,Ltd. |
| Magnavox Odyssey² cart. | Alien Invaders Plus! Model AA9428 | 1980 | Magnavox Co., The Fort Wayne, IN, USA |
| Apple II 5.25 disk | Alien Lander | 1980 | Sierra Soft. |
| Pinball | Alien Poker Model 501 | 1980 | Williams Mfg. Co. Chicago, IL, USA |
| Slot Machine | Alpha | 1980 | Compu-Games A.S. Esbjerg, Denmark |
| Commodore PET cass. | Alphabet | 1980 | Microcomputers in Education |
| Pinball | Amazing Spider-Man Model 653 | 1980 | Gottlieb & Co., D. Chicago, IL, USA |
| Arcade Video game | Ame Rug | 1980 | Shoei Co., Ltd. |
| Phillips Videopac cart. | American Football Model 3 | 1980 | Philips Corp. |
| Phillips Videopac cart. | American Football Model 3 | 1980 | Radiola La Radiotechnique Paris, France |
| Pachislot | Americana | 1980 | Universal Co., Ltd Tokyo, Japan |
| TRS-80 disk |  Android NIM Model 011-0036 | 1980 | Adventure International |
| Sharp MZ-80K type-in | Andromeda | 1980 | Dempa Shinbunsha Japan |
| Atari 400/800 disk | Angle Worms + Crolon Diversion Model 051-0092 | 1980 | Adventure International |
| Apple II cass. | Apple 21 Model BJD-378C | 1980 | Softape |
| Apple II 5.25 disk | Apple Galaxian | 1980 | Broderbund Soft., Inc. CA, USA 47956 |
| Apple II 5.25 disk | Apple Graphics Games | 1980 | Unknown |
| Apple II 5.25 disk | Apple Pairing | 1980 | Fan's Brother |
| Apple II 5.25 disk | Apple Stellar Invaders | 1980 | Apple Computer, Inc. |
| Apple II 5.25 disk | Apple World | 1980 | United Soft. of America |
| Bally Astrocade type-in | Arcade Golf | 1980 | Maslowski, Mike |
| Arcade Video game | Armor Attack | 1980 | Cinematronics, Inc. El Cajon, CA, USA |
| Arcade Video game | Armor Attack | 1980 | Rock-Ola Mfg. Corp. Chicago, IL, USA |
| Exidy Sorcerer cass. | Arrows and Alleys | 1980 | Quality Soft. Reseda, CA, USA |
| Bally Astrocade type-in | Artillery Duel | 1980 | Fabris, Robert San Jose, CA, USA |
| Pinball | Asteroid Annie and the Aliens Model 442 | 1980 | Gottlieb & Co., D. Chicago, IL, USA |
| Pinball | Asteroid Killer | 1980 | Universal Co., Ltd Tokyo, Japan |
| TRS-80 cass. | Asteroid Model 0247RD | 1980 | Instant Soft., Inc. |
| Apple II 5.25 disk | Asteroid Model 042-0015 | 1980 | Adventure International |
| Arcade Video game |  Asteroids | 1980 | Taito Corp. Japan |
