| Handheld game |  Racetime | 1980 | Bandai Co., Ltd. Japan |
| Handheld game | Racetrack Model 2374 | 1980 | Toytronic |
| Commodore C64 cart. | Radar Rat Race | 1980 | Commodore, Ltd. |
| Apple II 5.25 disk | RAF - The Battle of Britain | 1980 | Discovery Games |
| TRS-80 cass. | Rainbow's Casino | 1980 | Rainbow Computing, Inc. |
| Handheld game | Raise the Devil Pinball | 1980 | Sears Chicago, IL, USA |
| Pinball | Rally | 1980 | Taito do Brazil |
| Arcade Video game | Rally-X | 1980 | NAMCO, Ltd. Japan |
| Arcade Video game |  Rally-X Cocktail Table model Model 936 | 1980 | Midway Mfg. Co. Schiller Park, IL, USA |
| Arcade Video game | Rally-X Mini-Myte model Model 937 | 1980 | Midway Mfg. Co. Schiller Park, IL, USA |
| Arcade Video game | Rally-X Upright model Model 935 | 1980 | Midway Mfg. Co. Schiller Park, IL, USA |
| Sharp MZ-80K type-in | Reach Game | 1980 | Dempa Shinbunsha Japan |
| Tabletop game | Reader's Digest Q&A - Computer Question & Answer Game | 1980 | Reader's Digest Soft. |
| Arcade Video game | Red Dog Poker | 1980 | Sircoma Reno, NV, USA |
| Arcade Video game | Red Tank Cocktail Table model | 1980 | Sigma Enterprises, Inc. Tokyo, Japan |
| Arcade Video game | Red Tank Upright model | 1980 | Sigma Enterprises, Inc. Tokyo, Japan |
| TRS-80 type-in | Reflection | 1980 | SoftSide Publications, Inc. |
| Sharp MZ-80K type-in | Rejack | 1980 | ASCII Corp. Japan |
| Apple II cass. | Renju | 1980 | Tsukumo Denki Japan |
| Apple II 5.25 disk | Retro-Ball - Rocket Air Hockey Game | 1980 | Sierra Soft. |
| Apple II 5.25 disk | Reversal | 1980 | Hayden Book Co. |
| Commodore PET cass. | Reverse P | 1980 | Unknown |
| Atari 400/800 type-in | Ricochet | 1980 | SoftSide Publications, Inc. |
| Arcade Video game | Rip Off | 1980 | Cinematronics, Inc. El Cajon, CA, USA |
| Bally Astrocade type-in |  RND (Art) | 1980 | Fabris, Robert San Jose, CA, USA |
| UNIX soft. | Rogue - Exploring the Dungeons of Doom | 1980 | Unknown |
| Pinball | Roller Disco Model 440 | 1980 | Gottlieb & Co., D. Chicago, IL, USA |
| Arcade Video game | Rolling Crash 2 | 1980 | Nichibutsu Nihon Bussan Co., Ltd. Osaka, Japan |
| Pinball | Rolling Stones Model 1187 | 1980 | Bally Mfg. Co. Chicago, IL, USA |
| Apple II type-in | ROM the Robot Part Three | 1980 | SoftSide Publications, Inc. |
| Bally Astrocade type-in | Rotate | 1980 | Cursor Group, The |
| Slot Machine | Roulet | 1980 | Compu-Games A.S. Esbjerg, Denmark |
| Sharp MZ-80K type-in | Roulette Machine | 1980 | Dempa Shinbunsha Japan |
| RCA COSMAC VIP type-in | Russian Roulette | 1980 | Association of Computer Experimenters |
| TRS-80 type-in | Safari | 1980 | SoftSide Publications, Inc. |
| UNIX soft. | Sail | 1980 | Riggle & Wang |
| TRS-80 type-in | Sailplane | 1980 | SoftSide Publications, Inc. |
| Texas instrument TI-99/4A cart. | Salary Planner | 1980 | Foresman & Co., Scott |
| Arcade Video game | Samurai | 1980 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Phillips Videopac cart. | Samurai Model 15 | 1980 | Philips Corp. |
