| Phillips Videopac cart. |  Las Vegas Gambling Model 23 | 1980 | Magnavox Co., The Fort Wayne, IN, USA |
| Phillips Videopac cart. | Laser War Model 18 | 1980 | Philips Corp. |
| Tabletop game | Le Boom Model 9025 | 1980 | Lakeside |
| Compukit UK101 cass. | Le Passe-Temps | 1980 | Practical Electronics |
| TRS-80 cass. | Learning Fun I: Scurve Invaders | 1980 | Dick Smith Electronics |
| Bally Astrocade type-in | Life | 1980 | Keller, Mark S. |
| RCA COSMAC VIP type-in | Life for 1802! P | 1980 | Association of Computer Experimenters |
| TRS-80 disk | Life Two Model 011-0039 | 1980 | Adventure International |
| TRS-80 type-in | Line-Four | 1980 | SoftSide Publications, Inc. |
| Fruit Machine | Lite-a-Nudge | 1980 | JPM International |
| Handheld game | Live Action Football | 1980 | Kenner |
| Nascom cass. | Logichess | 1980 | Blue Label Soft. |
| TRS-80 type-in | Lone Star Corral | 1980 | SoftSide Publications, Inc. |
| Handheld game | Look Alive! Baseball Model 1996 | 1980 | Mattel Electronics Mattel, Inc. |
| Handheld game | Look Alive! Basketball Model 1997 | 1980 | Mattel Electronics Mattel, Inc. |
| Handheld game | Look Alive! Football Model 1998 | 1980 | Mattel Electronics Mattel, Inc. |
| Apple II/PET/TRS-80 cass. | Lords of Karma Model 40500 | 1980 | Microcomputer Games |
| Atari 800/Apple II/PET/TRS-80 cass. | Lords of Karma Model 40501 | 1980 | Microcomputer Games |
| TRS-80 type-in | Lost Dutchman's Gold | 1980 | SoftSide Publications, Inc. |
| Slot Machine | Low Boy Model 1208 | 1980 | Bally Mfg. Co. Chicago, IL, USA |
| Arcade Video game | Lucky Today | 1980 | Sigma Enterprises, Inc. Tokyo, Japan |
| Nascom cass. | Lumberjack | 1980 | Program Power |
| Sharp MZ-80K type-in | Lunar Lander | 1980 | ASCII Corp. Japan |
| Arcade Video game |  Lunar Rescue | 1980 | Taito America Corp. Elk Grove Village, IL, USA |
| Arcade Video game | Lunar Rescue | 1980 | Video Games, Ltd. Nottingham, England |
| Arcade Video game | Lupin III | 1980 | Taito Corp. Japan |
| TRS-80 disk | Lying Chimps Model 011-0037 | 1980 | Adventure International |
| Tabletop game | MAC Mini Computer | 1980 | Entex Industries, Inc. Compton, CA, USA |
| Arcade Video game | Mad Alien | 1980 | Data East Corp. Japan |
| TRS-80 type-in | Mad Scientist | 1980 | SoftSide Publications, Inc. |
| Pachinko | Magic Neon Challenge Ball | 1980 | Taiyo Co., Ltd. Japan |
| Arcade Video game | Magical Spot | 1980 | Universal Co., Ltd Tokyo, Japan |
| Arcade Video game | Magical Spot II | 1980 | Universal Co., Ltd Tokyo, Japan |
| Texas Instruments Speak & Spell mod. | Magnificent Modifiers Model CD2349 | 1980 | Texas Instruments |
| Slot Machine | Magnificent Seven Model 1207 | 1980 | Bally Mfg. Co. Chicago, IL, USA |
| Commodore PET cass. | Making an Outline | 1980 | Micro-Ed, Inc. |
| Bingo | Malibu Beach Model 1169 | 1980 | Bally Mfg. Co. Chicago, IL, USA |
| Slot Machine | Manhattan | 1980 | Wulff, Günter Berlin, Germany |
| Commodore PET cass. | Marching Capital Letters | 1980 | Micro-Ed, Inc. |
| Exidy Sorcerer cass. | Martian Invaders | 1980 | Quality Soft. Reseda, CA, USA |
