| Sega Mega Drive cart. |  007 Shitou - The Duel Model T-48073 | 1993 | Tengen, Inc. Milpilas, CA, USA |
| Sega Mega Drive cart. |  13 Ma Jiang - 98 Mei Shao Nu Pian 18 | 1998 | BBD |
| Sega Mega Drive cart. | 16Bit Rhythm Land Hb | 2019 | Columbus Circle Japan |
| Sega Mega Drive cart. | 2 Games on One Cart: Fantastic Dizzy + Cosmic Spacehead Model T-120044 | 1994 | Codemasters Soft. Co., Ltd., The 015026 |
| Sega Mega Drive cart. | 2020 Toshi Super Baseball Model EM20027 P | 1994 | Electronic Arts Victor, Inc. Japan |
| Sega Mega Drive cart. | 2048~16 Hb | 2014 | Titan |
| Sega Mega Drive cart. | 6-Pak Model 052020 | 1996 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | A Q Lian Huan Pao Model G-3051 | 1995 | C&E Computer & Ent., Inc. Taiwan |
| Sega Mega Drive cart. | A Ressha de Ikou MD - Take the A Train Model G-4532 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Aa Harimanada Model G-4086 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Aaahh!!! Real Monsters Model T-139066-50 | 1995 | Viacom New Media Viacom International, Inc. |
| Sega Mega Drive cart. | Addams Family Values Model T-164046-50 | 1995 | Ocean Soft., Ltd. 13156 |
| Sega Mega Drive cart. | Advanced Daisenryaku - Deutsch Dengeki Sakusen Model G-5505 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Adventurous Boy - Mao Xian Xiao Zi | 199? | Gamtec Taiwan |
| Sega Mega Drive cart. | Aero Blasters - Trouble Specialty Raid Unit Model T-33013 | 1991 | Kaneko Co., Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Aero the Acro-Bat 2 | 1994 | SUNSOFT Kounan, Japan |
| Sega Mega Drive cart. | Aero the Acro-Bat Model T-15056-50 | 1993 | SUNSOFT Kounan, Japan |
| Sega Mega Drive cart. | After Burner II P | 1990 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | After Burner II Model 1104-50 P | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | After Burner II Model T-17013 P | 1990 | Dempa Shinbunsha Japan |
| Sega Mega Drive cart. | Air Diver Model T-20023 | 1990 | Asmik Co., Ltd. Japan |
| Sega Mega Drive cart. | Air Management - Oozora ni Kakeru Model T-76083 | 1992 | KOEI Co., Ltd. Japan |
| Sega Mega Drive cart. | Air Management II - Koukuu Ou o Mezase Model T-76143 | 1994 | KOEI Co., Ltd. Japan |
| Sega Mega Drive cart. | Alex Kidd - Tenduu Mashiro Model G-4004 | 1989 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Alex Kidd in the Enchanted Castle | 1991 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Alex Kidd in the Enchanted Castle Model 1005-50 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Alien Soldier Model 1186-50 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Alien Soldier Model G-4130 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Alien Storm P | 1991 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Alien Storm Model 1121-50 P | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Alien Storm Model G-4048 P | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Alisia Dragoon Model 1039-50 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Alisia Dragoon Model T-45033 | 1992 | Game Arts Co., Ltd. Japan |
| Sega Mega Drive cart. | Altered Beast Model 042520 | 1990 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Altered Beast Model 1100-50 | 1989 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Andre AGASSI Tennis Model 043300 | 1992 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Andre AGASSI Tennis Model T-101016-50 | 1992 | TecMagik Ent., Ltd. |
| Sega Mega Drive cart. | Animaniacs Model T-95176-50 | 1994 | Konami Co., Ltd. Japan |
| Sega Mega Drive cart. | Another World Model T-70106-50 | 1993 | Virgin Games, Ltd. UK 013715 |
| Sega Mega Drive cart. | Aoki Ookami to Shiroki Mejika - Genchou Hishi Model T-76103 | 1993 | KOEI Co., Ltd. Japan |
