| Sega Mega Drive cart. |  Best of the Best - Championship Karate | 1993 | Electro Brain Corp. |
| Sega Mega Drive cart. |  Bill Walsh College Football Model E247SMX | 1993 | EA Sports |
| Sega Mega Drive cart. | Bill's Tomato Game | 199? | Psygnosis, Ltd. |
| Sega Mega Drive cart. | Bio Hazard Battle Model 1060-50 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. |  Bishoujo Senshi Sailormoon Model T-16043 | 1994 | Ma-Ba |
| Sega Mega Drive cart. | Block Out Model E175SMXI | 1991 | Electronic Arts CA, USA 14633 |
| Sega Mega Drive cart. | Blockout Model G-4059 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Bloodshot Model FBLO24SMC | 199? | SEGA OziSoft Australia |
| Sega Mega Drive cart. | Bloodshot Model T-88126-50 | 1994 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Sega Mega Drive cart. | Blue Almanac Model T-46013 | 1991 | Hot-B Japan |
| Sega Mega Drive cart. | Body Count | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Body Count | 1994 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Bomber | 2005 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Bomboy | 1993 | Gamtec Taiwan |
| Sega Mega Drive cart. | Bonanza Bros. P | 1991 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Bonanza Bros. Model 1124-50 P | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Bonanza Bros. Model G-4046 P | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Boogerman - A Pick and Flick Adventure Model T-125066-50 | 1994 | Interplay |
| Sega Mega Drive cart. | Boogerman Model FBOO01SMC | 199? | SEGA OziSoft Australia |
| Sega Mega Drive cart. | Boogie Woogie Bowling | 1993 | Visco Corp. Kyoto, Japan |
| Sega Mega Drive cart. | Boy Soccer Team III | 199? | Unknown |
| Sega Mega Drive cart. | Bram Stoker's Dracula | 1993 | Sony Imagesoft |
| Sega Mega Drive cart. | Brian Lara Cricket | 1995 | Codemasters Soft. Co., Ltd., The 015026 |
| Sega Mega Drive cart. | Brian Lara Cricket 96 | 1996 | Codemasters Soft. Co., Ltd., The 015026 |
| Sega Mega Drive cart. | Brutal - Paws of Fury Model T-83136-50 | 1994 | GameTek UK, Ltd. 026555 |
| Sega Mega Drive cart. | Bubba'n'Stix Model FBUB00SMC | 199? | SEGA OziSoft Australia |
| Sega Mega Drive cart. | Bubba'n'Stix Model T-115026-50 | 1994 | Core Design, Ltd. |
| Sega Mega Drive cart. | Bubble and Squeak | 1994 | SUNSOFT Kounan, Japan |
| Sega Mega Drive cart. | Buck Rogers - Countdown to Doomsday | 1992 | Electronic Arts CA, USA 14633 |
| Sega Mega Drive cart. | Budokan | 1991 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Budokan - The Martial Spirit Model E117SMXI | 1990 | Electronic Arts CA, USA 14633 |
| Sega Mega Drive cart. | Bugs Bunny in Double Trouble Model 051050 | 1996 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Bugs Bunny in Double Trouble Model MK-1840-50 | 1996 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Burning Force | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Burning Force Model T-14023 | 1990 | NAMCOT Japan |
| Sega Mega Drive cart. | Caesar no Yabou II Model T-22063 | 1992 | Micronet Co., Ltd. Japan |
| Sega Mega Drive cart. | Caesar no Yabou Model T-22033 | 1991 | Micronet Co., Ltd. Japan |
| Sega Mega Drive cart. | Cannon Fodder | 1994 | Virgin Interactive Ent., Ltd. UK 013715 |
| Sega Mega Drive cart. | Cannon Fodder Model FCAN00SMC | 199? | SEGA OziSoft Australia |
| Sega Mega Drive cart. | Capt'n Havoc | 1994 | Codemasters Soft. Co., Ltd., The 015026 |
