| Sega Mega Drive cart. |  Mega Games 3 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Mega Games 6 Vol. 1 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Mega Games 6 Vol. 2 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Mega Games 6 Vol. 3 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Mega Games I | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. |  Mega Kids: The Berenstain Bears' Camping Adventure | 1993 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Mega Man - The Wily Wars Model T-2046-50 | 1994 | Capcom Co., Ltd. Japan |
| Sega Mega Drive cart. | Mega SWIV | 1994 | Time Warner Interactive |
| Sega Mega Drive cart. | Mega Turrican Model T-93246-50 | 1994 | Sony Imagesoft |
| Sega Mega Drive cart. | Mega-Lo-Mania Model T-68053 | 1993 | CRI CSK Research Institute Japan |
| Sega Mega Drive cart. | Mega-Lo-Mania Model T-70056-50 | 1992 | Virgin Games, Ltd. UK 013715 |
| Sega Mega Drive cart. | MegaPanel | 1990 | NAMCOT Japan |
| Sega Mega Drive cart. | MegaTrax Model T-14113 | 1991 | NAMCOT Japan |
| Sega Mega Drive cart. | Meng Huan Shui Guo Pan - 777 Casino | 199? | City Man China |
| Sega Mega Drive cart. | Mercs | 1992 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Mercs Model 1119-50 P | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Metal Fangs Model T-60033 | 1993 | Victor Musical Industries, Inc. Japan |
| Sega Mega Drive cart. | Michael Jackson's Moonwalker Model G-4028 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Mick & Mack as the Global Gladiators Model T-70066-50 | 1993 | Virgin Games, Ltd. UK 013715 |
| Sega Mega Drive cart. | Mickey Mania - The Timeless Adventures of Mickey Mouse Model G-4131 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Mickey Mania - The Timeless Adventures of Mickey Mouse Model T-93216-50 | 1994 | Sony Imagesoft |
| Sega Mega Drive cart. | Micro Machines - Turbo Tournament '96 Model T-120126-50 | 1995 | Codemasters Soft. Co., Ltd., The 015026 |
| Sega Mega Drive cart. | Micro Machines 2 - Turbo Tournament Model T-120096-50 | 1994 | Codemasters Soft. Co., Ltd., The 015026 |
| Sega Mega Drive cart. | Micro Machines Military Model T-1201166-50 | 1996 | Codemasters Soft. Co., Ltd., The 015026 |
| Sega Mega Drive cart. | Micro Machines Model T120016-50 | 1993 | Codemasters Soft. Co., Ltd., The 015026 |
| Sega Mega Drive cart. | Midnight Resistance Model T-13043 P | 1991 | Data East Corp. Japan |
| Sega Mega Drive cart. | Mig-29 Fighter Pilot Model T-48133 | 1993 | Tengen, Inc. Milpilas, CA, USA |
| Sega Mega Drive cart. | Mig-29 Fighter Pilot Model T-88026-50 | 1993 | Domark Group, Ltd. |
| Sega Mega Drive cart. | Might and Magic - Gates to Another World | 1991 | Electronic Arts CA, USA 14633 |
| Sega Mega Drive cart. | Mighty Morphin Power Rangers | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Mighty Morphin Power Rangers - The Movie | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Minato no Traysia Model T-49073 | 1992 | Riot Japan |
| Sega Mega Drive cart. | Monster World IV Model G-5519 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Mortal Kombat - Shinken Kourin Densetsu Model T-81014 | 1994 | Acclaim Japan |
| Sega Mega Drive cart. | Mortal Kombat 3 Model 050010 | 1995 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Mortal Kombat 3 Model T-81536-50 | 1995 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Sega Mega Drive cart. | Mortal Kombat II Model 047070 | 1994 | Tec Toy Industria de Brinquedos S.A. Brazil |
| Sega Mega Drive cart. | Mortal Kombat II Model FMOR01SMC | 1994 | SEGA OziSoft Australia |
| Sega Mega Drive cart. | Mortal Kombat II Model T-8104A P | 1994 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Sega Mega Drive cart. | Mortal Kombat II Model T-81346-50 | 1994 | Acclaim Ent., Inc. Glen Cove, NY, USA |
