| Sharp X68000 Series 5.25in. disk |  Dog Fight! | 1992 | Biwahosi Soft. |
| Sharp X68000 Series 5.25in. disk | Doki Doki Amanachan | 1990 | Toy Pops |
| Sharp X68000 Series 5.25in. disk | Doki Doki Card League | 1990 | Great Japan |
| Sharp X68000 Series 5.25in. disk | Dome | 1988 | System Sacom Corp. Japan |
| Sharp X68000 Series 5.25in. disk | Door Door P | 1990 | Chun Soft |
| Sharp X68000 Series 5.25in. disk | DOR 18 | 1992 | DO Corp. Japan |
| Sharp X68000 Series 5.25in. disk | DOR Part 2 18 | 1992 | DO Corp. Japan |
| Sharp X68000 Series 5.25in. disk | DOR Part 3 18 | 1992 | DO Corp. Japan |
| Sharp X68000 Series 5.25in. disk | DOR Special Edition '93 18 | 1993 | DO Corp. Japan |
| Sharp X68000 Series 5.25in. disk | DOR Special Edition Sakigake 18 | 1993 | DO Corp. Japan |
| Sharp X68000 Series 5.25in. disk | Dori Dor Qizu | 1993 | Daikokuya Dennou |
| Sharp X68000 Series 5.25in. disk | Dorix | 1998 | YoKoMuMu |
| Sharp X68000 Series 5.25in. disk | Double Eagle | 1988 | Artdink Corp. Japan |
| Sharp X68000 Series 5.25in. disk | Double Eagle - Tricky Hole | 198? | Artdink Corp. Japan |
| Sharp X68000 Series 5.25in. disk | Double Target | 1990 | Proceed Japan |
| Sharp X68000 Series 5.25in. disk | Doukyuusei 18 | 1992 | Elf Japan |
| Sharp X68000 Series 5.25in. disk | Downtown Nekketsu Monogatari Model CZ-254AS P | 1990 | Sharp Japan |
| Sharp X68000 Series 5.25in. disk | Dr. A San Kyoudai Series Tomomichan no Dobon | 199? | Unknown Japan |
| Sharp X68000 Series 5.25in. disk | Dr. Orima | 1990 | Halman |
| Sharp X68000 Series 5.25in. disk | Dr. Stop! 18 | 1992 | Alicesoft Japan |
| Sharp X68000 Series 5.25in. disk | Dracula Hakushaku - Bishoujo-tachi no Chi no Shitatari 18 | 1992 | IDES Japan |
| Sharp X68000 Series 5.25in. disk | Dragon | 1989 | LOG Japan |
| Sharp X68000 Series 5.25in. disk | Dragon City X Shitei | 1991 | IDES Japan |
| Sharp X68000 Series 5.25in. disk | Dragon Cross | 19?? | Masqurade |
| Sharp X68000 Series 5.25in. disk | Dragon Eyes 18 | 1991 | Game Technopolis Japan |
| Sharp X68000 Series 5.25in. disk | Dragon Knight 18 | 1989 | Elf Japan |
| Sharp X68000 Series 5.25in. disk | Dragon Knight 4 18 | 1994 | Elf Japan |
| Sharp X68000 Series 5.25in. disk | Dragon Knight 4 - Special Disk | 1994 | Elf Japan |
| Sharp X68000 Series 5.25in. disk | Dragon Knight II 18 | 1991 | Elf Japan |
| Sharp X68000 Series 5.25in. disk | Dragon Knight III | 1992 | Elf Japan |
| Sharp X68000 Series 5.25in. disk | Dragon Knight III for Adult 18 | 1992 | Elf Japan |
| Sharp X68000 Series 5.25in. disk | Dragon Province | 199? | Justice Japan |
| Sharp X68000 Series 5.25in. disk | Dragon Quest | 1992 | Mitsuru Kamiyama |
| Sharp X68000 Series 5.25in. disk | Dragon Slayer | 1995 | SPS Japan |
| Sharp X68000 Series 5.25in. disk | Dragon Slayer - Eiyuu Densetsu Model GS-204 | 1993 | SPS Japan |
| Sharp X68000 Series 5.25in. disk | Dragon Spirit Model DP-3205006 P | 1988 | Dempa Shinbunsha Japan |
| Sharp X68000 Series 5.25in. disk | Dragon Wars | 1991 | Starcraft, Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Drakkhen | 1991 | Epic/Sony Records Sony Music Ent., Inc. Japan |
| Sharp X68000 Series 5.25in. disk | Drinky & Smokey | 1994 | Dream Staff |
| Sharp X68000 Series 5.25in. disk | Dual Targets - The 4th Unit Act. 3 | 1989 | Data West, Inc. Japan |
