| NEC PC-9801 Series 5.25in. disk |  Concert | 1994 | Aypio Japan |
| NEC PC-9801 Series 5.25in. disk | Construction Tool - Maze-kun | 1989 | Telenet Japan |
| NEC PC-9801 Series 5.25in. disk | Constructors Grand Prix | 1992 | Soft Studio Wing Japan |
| NEC PC-9801 Series 5.25in. disk | Continental - Bishoujo RPG 18 | 1992 | Game Technopolis Japan |
| NEC PC-9801 Series 5.25in. disk | Corpse Party | 1996 | Kenix Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | Cosmic Psycho | 1991 | Cocktail Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | Cosmic Soldier | 1985 | Kogado Studio Japan |
| NEC PC-9801 Series 5.25in. disk | Cosmos Club 18 | 1988 | Jast Japan |
| NEC PC-9801 Series 5.25in. disk | Cranston Manor | 1983 | Starcraft, Inc. Japan |
| NEC PC-9801 Series 5.25in. disk | Cray Shoot | 199? | Bio 100% Japan |
| NEC PC-9801 Series 5.25in. disk | Crazy Labyrinth | 199? | Cats' Organization Japan |
| NEC PC-9801 Series 5.25in. disk | Cream Lemon - Star Trap 18 | 1987 | Jast Japan |
| NEC PC-9801 Series 5.25in. disk | CrEastar - Planets in Legend | 1989 | Bothtec, Inc. Japan |
| NEC PC-9801 Series 5.25in. disk | Crescent 18 | 1993 | Silky's Japan |
| NEC PC-9801 Series 5.25in. disk | Crescent Moon Girl 18 | 1989 | Alicesoft Japan |
| NEC PC-9801 Series 5.25in. disk | Crimson III | 1990 | Xtal Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | Cross Changer 18 | 1994 | Ucom Japan |
| NEC PC-9801 Series 5.25in. disk | Cruise Chaser - Blassty | 1986 | Square Co., Ltd. Japan |
| NEC PC-9801 Series 5.25in. disk | Crusher Joe - Kanraku Wakusei no Inbou | 1994 | Family Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | CRW - Metal Jacket | 1994 | Wiz Japan |
| NEC PC-9801 Series 5.25in. disk | CRW 2 | 1995 | Wiz Japan |
| NEC PC-9801 Series 5.25in. disk | Crystal Chaser - Tenkuu no Mashoukyuu | 1991 | Telenet Japan |
| NEC PC-9801 Series 5.25in. disk | Crystal Dream | 1989 | Striker Japan |
| NEC PC-9801 Series 5.25in. disk | Crystal Dream II - Maou no Genei | 1990 | Striker Japan |
| NEC PC-9801 Series 5.25in. disk | Crystal Quest | 1992 | Pixy Bell Japan |
| NEC PC-9801 Series 5.25in. disk | Crystal Rinal - Ouma no Meikyuu 18 | 1994 | DO Corp. Japan |
| NEC PC-9801 Series 5.25in. disk | Curse | 1994 | Queensoft Japan |
| NEC PC-9801 Series 5.25in. disk | Curse of Castle | 199? | Elf Japan |
| NEC PC-9801 Series 5.25in. disk | Custom Mate | 1993 | Cocktail Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | Custom Mate 2 | 1994 | Cocktail Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | Custom Mate 3 | 1995 | Cocktail Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | Cutie Cop Quiz - Nusumareta File no Nazo | 1994 | Ice Japan |
| NEC PC-9801 Series 5.25in. disk | Cyber Illusion 18 | 1995 | Pearl Soft. Japan |
| NEC PC-9801 Series 5.25in. disk | Cyber School 98 | 1992 | Low Tech Team Japan |
| NEC PC-9801 Series 5.25in. disk | Cyber Vaccine Itekomashi | 199? | Nichikon Japan |
| NEC PC-9801 Series 5.25in. disk | Cyber Writer DX | 199? | Unknown Japan |
| NEC PC-9801 Series 5.25in. disk | CyberBlock Metal Orange 18 | 1991 | Cybertech Custom Japan |
| NEC PC-9801 Series 5.25in. disk | Cybernoid Alpha | 1995 | DO Corp. Japan |
| NEC PC-9801 Series 5.25in. disk | D - Oushuu Shinkirou | 1990 | Wolf Team Japan |
| NEC PC-9801 Series 5.25in. disk | D'ark | 1992 | Himeya Soft., Inc. Japan |
