| Nintendo GameCube disc |  Rune II | 2003 | From Soft. |
| Nintendo GameCube disc | Shikigami no Shiro 2 Model DOL-G2SJ-JPN | 2003 | Kids Station |
| Nintendo GameCube disc | Shonen Jump's Naruto - Clash of Ninja | 2003 | Tomy |
| Nintendo GameCube disc | Shrek Super Party | 2003 | TDK Mediactive, Inc. |
| Nintendo GameCube disc | Skies of Arcadia Legends Model DOL-GEAE-USA | 2003 | SEGA of America, Inc. San Francisco, CA, USA |
| Nintendo GameCube disc | Skies of Arcadia Legends Model DOL-GEAP-EUR | 2003 | SEGA Europe Ltd. |
| Nintendo GameCube disc | Sonic Adventure DX - Director's Cut Model DOL-GXSE-USA | 2003 | SEGA of America, Inc. San Francisco, CA, USA |
| Nintendo GameCube disc | Sonic Adventure DX - Director's Cut Model DOL-GXSP-EUR | 2003 | SEGA Europe Ltd. |
| Nintendo GameCube disc | Sonic Heroes | 2003 | SEGA Corp. |
| Nintendo GameCube disc | Sonic Mega Collection Model DOL-GSOP-EUR | 2003 | Infogrames Europe 546430 |
| Nintendo GameCube disc | SoulCalibur II | 2003 | NAMCO, Ltd. Japan |
| Nintendo GameCube disc | SoulCalibur II Model DOL-GRSE-USA | 2003 | NAMCO Hometek, Ltd. USA |
| Nintendo GameCube disc |  SoulCalibur II Model DOL-GRSP-EUR | 2003 | Nintendo Co., Ltd. Japan |
| Nintendo GameCube disc | Spawn Armageddon Model DOL-GPWE-USA | 2003 | NAMCO Hometek, Ltd. USA |
| Nintendo GameCube disc | Speed Kings Model DOL-GDCE-USA | 2003 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Nintendo GameCube disc | Sphinx and the Cursed Mummy | 2003 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo GameCube disc | Spider-Man | 2003 | Capcom Co., Ltd. Japan |
| Nintendo GameCube disc | Spirits & Spells | 2003 | DreamCatcher Interactive |
| Nintendo GameCube disc | SpongeBob SquarePants - Battle for Bikini Bottom Model DOL-GQPE-USA | 2003 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo GameCube disc | SSX 3 Model DOL-GXBE-USA | 2003 | Electronic Arts CA, USA 14633 |
| Nintendo GameCube disc | Star Wars Rogue Squadron III - Rebel Strike Model DOL-GLRE-USA | 2003 | LucasArts Ent. Co. |
| Nintendo GameCube disc | Star Wars Rogue Squadron III - Rebel Strike Model DOL-GLRP-EUR | 2003 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo GameCube disc | Starsky & Hutch | 2003 | Empire Interactive Europe, Ltd. |
| Nintendo GameCube disc | Summoner - A Goddess Reborn Model DOL-GS2E-USA | 2003 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo GameCube disc | Superman - Shadow of Apokolips Model DOL-GSUP-EUR | 2003 | Infogrames Europe 546430 |
| Nintendo GameCube disc | SX Superstar | 2003 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Nintendo GameCube disc | Tak and the Power of Juju Model DOL-GJUE-USA | 2003 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo GameCube disc | Tales of Symphonia Model DOL-GTOJ-JPN | 2003 | NAMCO, Ltd. Japan |
| Nintendo GameCube disc | Teenage Mutant Ninja Turtles Model DOL-GTFE-USA | 2003 | Konami of America CA, USA |
| Nintendo GameCube disc | Tengai Makyou II - Manjimaru Model DOL-GT2J-JPN | 2003 | Hudson Soft. Hudson Group Japan |
| Nintendo GameCube disc | The Hobbit Model DOL-GHBE-USA | 2003 | Sierra Ent., Inc. USA |
| Nintendo GameCube disc | The Italian Job | 2003 | Eidos Interactive |
| Nintendo GameCube disc | The Legacy of Kain Series - Blood Omen 2 Model DOL-GO2D-NOE | 2003 | Eidos Interactive |
| Nintendo GameCube disc | The Legend of Zelda - Collector's Edition Model DOL-PZLE-USA | 2003 | Nintendo of America, Inc. USA 45496 |
| Nintendo GameCube disc | The Legend of Zelda - Ocarina of Time + Master Quest Model DOL-D43E-USA | 2003 | Nintendo of America, Inc. USA 45496 |
| Nintendo GameCube disc | The Legend of Zelda - The Wind Waker Model DOL-GZLE-USA | 2003 | Nintendo of America, Inc. USA 45496 |
| Nintendo GameCube disc | The Legend of Zelda - The Wind Waker Model DOL-GZLP-EUR | 2003 | Nintendo Co., Ltd. Japan |
| Nintendo GameCube disc | The Lord of the Rings - The Return of the King Model DOL-GKLD-NOE | 2003 | Electronic Arts CA, USA 14633 |
| Nintendo GameCube disc | The Lord of the Rings - The Return of the King Model DOL-GKLE-USA | 2003 | Electronic Arts CA, USA 14633 |
| Nintendo GameCube disc | The Lord of the Rings - The Two Towers Model DOL-GLOD-NOE | 2003 | Electronic Arts CA, USA 14633 |
