| LeapFrog Leapster cart. |  Demo - Herbst 2004 II | 2003 | LeapFrog |
| Sammy Atomiswave cart. | Demolish Fist | 2003 | Sammy Corp. Japan |
| PC/MS-Windows CD | Demolition Champions | 2003 | ValuSoft |
| Nintendo GBA cart. | Densetsu no Stafy 2 Model AGB-AVFJ-JPN | 2003 | Nintendo Co., Ltd. Japan |
| Slot Machine | Denver | 2003 | Mega |
| Slot Machine | Denver Duck and the Quest for the Golden Egg | 2003 | IGT International Game Technologies Reno, NV, USA |
| Pachislot | Derby Boy | 2003 | Sammy Corp. Japan |
| Pachinko | Deruderu Monster | 2003 | Sammy Corp. Japan |
| PC/MS-Windows CD | Des Blood VR | 2003 | Illusion Japan |
| Sony PlayStation CD |  Destructo 2 Model SLES-04073 | 2003 | Phoenix Games |
| Sony PlayStation CD | Detective Mouse Model SLES-04130 | 2003 | Phoenix Games |
| PC/MS-Windows CD | Deus Ex - Invisible War | 2003 | Eidos Interactive |
| Microsoft XBOX disc | Deus Ex - Invisible War | 2003 | Unknown |
| Nintendo GBA cart. | Deutschland Sucht den Superstar | 2003 | Codemasters Soft. Co., Ltd., The 015026 |
| Sony PlayStation 2 disc | Devil May Cry 2 Model SLPM-65232~3 | 2003 | Capcom Co., Ltd. Japan |
| Pachinko | Devilman club | 2003 | Newgin Japan |
| Slot Machine | Diamond Bar | 2003 | Unknown Korea |
| Slot Machine | Diamond Bar V1 | 2003 | Unknown Korea |
| Slot Machine | Diamond Bar V2 | 2003 | Unknown Korea |
| Slot Machine | Diamond Bar V3 | 2003 | Unknown Korea |
| Slot Machine | Diamond Line Frenzy | 2003 | Bally Gaming, Inc. Las Vegas, NV, USA |
| Slot Machine | Diamond Solitaire | 2003 | Konami Gaming, Inc. Las Vegas, NV, USA |
| Slot Machine | Diamonds in the Rough | 2003 | WMS Gaming, Inc. Chicago, IL, USA |
| Microsoft XBOX disc | Die Hard - Vendetta | 2003 | Unknown |
| LeapFrog Leapster cart. | Digging for Dinosaurs | 2003 | LeapFrog |
| Nintendo GBA cart. | Digimon - Battle Spirit 2 Model AGB-BDSE-USA | 2003 | Bandai America, Inc. 45557 |
| Nintendo GBA cart. | Digimon - Battle Spirit 2 Model AGB-BDSP | 2003 | Bandai Co., Ltd. Japan |
| Nintendo GBA cart. | Digimon - Battle Spirit Model AGB-A8SE-USA | 2003 | Bandai America, Inc. 45557 |
| Nintendo GBA cart. | Digimon - Battle Spirit Model AGB-A8SP | 2003 | Bandai Co., Ltd. Japan |
| Nintendo GBA cart. | Digimon Ruby | 2003 | Unknown China |
| Microsoft XBOX disc | Dino Crisis 3 | 2003 | Unknown |
| Medal video game | Dino King II | 2003 | Taito Corp. Japan |
| Video Slot Machine | Dinosaur | 2003 | Aristocrat Leisure Industries Pty, Ltd. |
| Sony PlayStation CD | Dinosaurs Model SLES-04063 | 2003 | Phoenix Games |
| Microsoft XBOX disc | Dinotopia - The Sunstone Odyssey | 2003 | Unknown |
| Sony PlayStation CD | Dirt Jockey - Heavy Equipment Operator Model SLUS-01552 | 2003 | Mastiff, LLC |
| PC/MS-Windows CD | Disciples II - Guardians of the Light | 2003 | Strategy First |
| PC/MS-Windows CD | Disciples II - Rise of the Elves | 2003 | Strategy First |
| PC/MS-Windows CD | Disciples II - Servants of the Dark | 2003 | Strategy First |
| Sony PlayStation CD | Disney El planeta del tesoro Model SCES-03941 | 2003 | Sony Computer Ent. Europe SCEE |
