| Nintendo 64 cart. |  Carnivalé - Cenzo's Adventure | 2000 | Vatical Ent. |
| Nintendo 64 cart. |  Castlevania - Legacy of Darkness | 2000 | Konami Co., Ltd. Japan |
| Nintendo 64 cart. | Cruis'n Exotica | 2000 | Midway Home Ent. |
| Nintendo 64 cart. | Custom Robo V2 Model NUS-NCZJ | 2000 | Nintendo Co., Ltd. Japan |
| Nintendo 64 cart. | CyberTiger | 2000 | Electronic Arts CA, USA 14633 |
| Nintendo 64 cart. | Daffy Duck Starring as Duck Dodgers | 2000 | Infogrames Interactive, Inc. 329720 |
| Nintendo 64 cart. | Dance Dance Revolution - Disney Dancing Museum Model NUS-NDFJ | 2000 | Konami Co., Ltd. Japan |
| Nintendo 64 cart. | Die Hard 64 | 2000 | Fox Interactive |
| Nintendo 64 cart. | Donald Duck - Goin' Quackers | 2000 | UBI Soft Creteil, France 307211 |
| Nintendo 64 cart. | Donald Duck - Quack Attack | 2000 | UBI Soft Creteil, France 307211 |
| Nintendo 64 cart. |  Donkey Kong 64 Model NUS-NDOP-AUS | 2000 | Nintendo Australia Pty, Ltd. |
| Nintendo 64 cart. | Doraemon 3 - Nobita no Machi SOS! Model NUS-ND3J | 2000 | Epoch Co., Ltd. Tokyo, Japan |
| Nintendo 64 cart. | Duck Dodgers Starring Daffy Duck | 2000 | Infogrames Interactive, Inc. 329720 |
| Nintendo 64 cart. | ECW Hardcore Revolution | 2000 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Nintendo 64 cart. | Excitebike 64 Model NUS-NMXE-USA | 2000 | Nintendo of America, Inc. USA 45496 |
| Nintendo 64 cart. | Excitebike 64 Model NUS-NMXJ | 2000 | Nintendo Co., Ltd. Japan |
| Nintendo 64 cart. | F1 Racing Championship | 2000 | UBI Soft Creteil, France 307211 |
| Nintendo 64 cart. | Fighter Destiny 2 | 2000 | SouthPeak Interactive, LLC |
| Nintendo 64 cart. | Fushigi no Dungeon - Fuurai no Shiren 2 - Oni Shuurai! Shiren Jou! Model NUS-NSIJ-JPN | 2000 | Nintendo Co., Ltd. Japan |
| Nintendo 64 cart. | Ganbare! Nippon! Olympics 2000 Model NUS-N3HJ | 2000 | Konami Co., Ltd. Japan |
| Nintendo 64 cart. | Gauntlet Legends Model NUS-NGDJ | 2000 | Epoch Co., Ltd. Tokyo, Japan |
| Nintendo 64 cart. | Hercules - The Legendary Journeys | 2000 | Titus Gagny, France |
| Nintendo 64 cart. | Hey You, Pikachu! Model NUS-NPGE-USA | 2000 | Nintendo of America, Inc. USA 45496 |
| Nintendo 64 cart. | Hoshi no Kirby 64 Model NUS-NK4J | 2000 | Nintendo Co., Ltd. Japan |
| Nintendo 64 cart. | Hydro Thunder Model NUS-NHTE-USA | 2000 | Midway Home Ent. |
| Nintendo 64 cart. | Hydro Thunder Model NUS-NHTP-EUR | 2000 | Midway Home Ent. |
| Nintendo 64 cart. | Ide Yousuke no Mahjong Juku Model NUS-NIMJ | 2000 | Seta Co., Ltd. Japan |
| Nintendo 64 cart. | Indiana Jones and the Infernal Machine | 2000 | LucasArts Ent. Co. |
| Nintendo 64 cart. | Indy Racing 2000 | 2000 | Infogrames Interactive, Inc. 329720 |
| Nintendo 64 cart. | International Superstar Soccer 2000 | 2000 | Konami Co., Ltd. Japan |
| Nintendo 64 cart. | International Track & Field - Summer Games | 2000 | Konami Co., Ltd. Japan |
| Nintendo 64 cart. | International Track & Field 2000 | 2000 | Konami Co., Ltd. Japan |
| Nintendo 64 cart. | Itoi Shigesato no Bass Tsuri No. 1 Kettei Ban! Model NUS-NIBJ | 2000 | Nintendo Co., Ltd. Japan |
| Nintendo 64 cart. | Jeremy McGrath Supercross 2000 | 2000 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Nintendo 64 cart. | Jikkyou Powerful Pro Yakyuu 2000 Model NUS-NPAJ | 2000 | Konami Co., Ltd. Japan |
| Nintendo 64 cart. | John Romero's Daikatana | 2000 | Kemco, Ltd. |
| Nintendo 64 cart. | John Romero's Daikatana Model NUS-NDWJ | 2000 | Kemco, Ltd. |
| Nintendo 64 cart. | Kirby 64 - The Crystal Shards Model NUS-NK4E-USA | 2000 | Nintendo of America, Inc. USA 45496 |
| Nintendo 64 cart. | Madden NFL 2001 | 2000 | Electronic Arts CA, USA 14633 |
| Nintendo 64 cart. | Mario Party 2 | 2000 | Nintendo Co., Ltd. Japan |
