| NEC PC-Engine HuCARD |  Gradius Model KM91001 | 1991 | Konami Industry Co., Ltd. Japan |
| NEC PC-Engine HuCARD | Hanata-Kadaka!? Model TP03018 | 1991 | Taito Corp. Japan |
| NEC PC-Engine HuCARD | Hatris | 1991 | Tengen, Inc. Milpilas, CA, USA |
| NEC PC-Engine HuCARD | Hit the Ice Model TP03019 | 1991 | Taito Corp. Japan |
| NEC PC-Engine HuCARD | Hyper Shooting DEAD MOON - Tsuki Sekai no Akumu Model TS91001 | 1991 | TSS |
| NEC PC-Engine HuCARD | Idol Hanafuda Fan Club | 1991 | Games Express |
| NEC PC-Engine HuCARD | Jackie Chan Model HC90032 | 1991 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | Kaizou Choujin Shubibinman 2 - Aratanaru Teki Model NCS91001 | 1991 | Masaya |
| NEC PC-Engine HuCARD | Legend of Hero Tonma Model IC03005 P | 1991 | Irem Corp. Japan |
| NEC PC-Engine HuCARD | Magical Chase Model PL91001 | 1991 | Palsoft |
| NEC PC-Engine HuCARD | Mesopotamia Model AT03001 | 1991 | Atlus Co., Ltd. Japan |
| NEC PC-Engine HuCARD | Metal Stoker Model FA03-009 | 1991 | Face Co., Ltd. Tokyo, Japan |
| NEC PC-Engine HuCARD | Monster Pro Wres Model AK91002 | 1991 | ASK Kodansha Co., Ltd. Japan |
| NEC PC-Engine HuCARD | Morita Shougi PC Model NAPH-1021 | 1991 | NEC Avenue, Ltd. Japan |
| NEC PC-Engine HuCARD | Moto Roader II | 1991 | Masaya |
| NEC PC-Engine HuCARD | Neutopia II Model HC91047 | 1991 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | NHK Okaasan to Issho Niko Niko, Pun Model NV91001 | 1991 | NHK Enterprise |
| NEC PC-Engine HuCARD | Obocchama-kun Model NC91001 | 1991 | NAMCOT Japan |
| NEC PC-Engine HuCARD | Override Model DE90006 | 1991 | Data East Corp. Japan |
| NEC PC-Engine HuCARD | Parasol Stars - The Story of Bubble Bobble III Model TP03017 | 1991 | Taito Corp. Japan |
| NEC PC-Engine HuCARD | PC Genjin 2 Model HC91043 | 1991 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | Populous Model HC91041 | 1991 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | Power Eleven Model HC91039 | 1991 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | Power Gate Model PV1008 | 1991 | Pack-In-Video Co., Ltd. Japan |
| NEC PC-Engine HuCARD | Power League IV Model HC91046 | 1991 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | Pro Yakyuu World Stadium '91 | 1991 | NAMCOT Japan |
| NEC PC-Engine HuCARD | Puzzle Boy | 1991 | Telenet Japan |
| NEC PC-Engine HuCARD | Racing Damashii Model IC03006 | 1991 | Irem Corp. Japan |
| NEC PC-Engine HuCARD | Raiden Model HC91049 P | 1991 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | S.C.I. - Special Criminal Investigation Model TP03016 | 1991 | Taito Corp. Japan |
| NEC PC-Engine HuCARD | Salamander Model KM91002 P | 1991 | Konami Industry Co., Ltd. Japan |
| NEC PC-Engine HuCARD | Shougi Shoshinsha Muyou | 1991 | Home Data Japan |
| NEC PC-Engine HuCARD | Silent Debuggers Model DE90004 | 1991 | Data East Corp. Japan |
| NEC PC-Engine HuCARD | Skweek Model JC63011 | 1991 | Victor Musical Industries, Inc. Japan |
| NEC PC-Engine HuCARD | Spiral Wave | 1991 | Media Rings Corp. Japan |
| NEC PC-Engine HuCARD | Super Metal Crusher | 1991 | Pack-In-Video Co., Ltd. Japan |
| NEC PC-Engine HuCARD | Super Momotarou Dentetsu II | 1991 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | Tennokoe Bank | 1991 | Hudson Soft. Hudson Group Japan |
| NEC PC-Engine HuCARD | Time Cruise II Model FA03-010 | 1991 | Face Co., Ltd. Tokyo, Japan |
| NEC PC-Engine HuCARD | Titan | 1991 | Naxat Soft. Japan |
