| Sega Mega Drive cart. |  Pro Striker Final Stage Model G-5547 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Pro Yakyuu Super League '91 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Pulseman Model G-4098 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Puyo Puyo Model G-4082 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Pyramid Magic II | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | QuackShot - I Love Donald Duck - Guruzia Ou no Hihou Model G-4054 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. |  QuackShot starring Donald Duck | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Rambo III | 1989 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Ranger-X Model 1076-50 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Rent a Hero Model G-5508 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Richard Scarry's Busytown | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Ristar - The Shooting Star Model G-4126 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Ristar Model 1555-50 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Rolling Thunder 2 P | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Ryuuko no Ken Model G-4113 P | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Samurai Spirits Model G-4127 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Sangokushi Retsuden - Ransei no Eiyuutachi Model G-5504 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Scholastic's The Magic School Bus | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Sega Gold Collection: Street Fighter II' - Special Champion Edition | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Sega Sports 1 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Senjou no Ookami II Model G-4051 P | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shadow Dancer - The Secret of Shinobi Model G-4043 | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shadowrun | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shin Souseiki Ragnacenty Model G-5536 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shining and the Darkness Model G-5506 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shining Force - Kamigami no Isan Model G-5512 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shining Force - The Legacy of Great Intention Model 1312-03 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shining Force II - Koe no Fuuin Model G-5521 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shining Force II Model 1315-03 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shining in the Darkness Model 1310-50 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shinobi III - Return of the Ninja Master Model 1136-50 | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Shura no Mon Model G-4073 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Side Pocket Model 670-2893-50 | 1992 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Snake Rattle n' Roll | 1993 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Soleil Model 1182-05 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Soleil Model 1182-06 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Soleil Model 1182-09 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Soleil Model 1182-18 | 1995 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Sonic & Knuckles Model 1563-50 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Mega Drive cart. | Sonic & Knuckles Model G-4124 | 1994 | SEGA Enterprises, Ltd. Tokyo, Japan |
