| Sony PlayStation CD |  Sentinel Returns Model SLES-01051 | 1998 | Psygnosis, Ltd. |
| Sony PlayStation CD |  Sentinel Returns Model SLUS-00604 | 1998 | Psygnosis, Ltd. |
| Sony PlayStation CD | Serial Experiments Lain Model SLPS-01603~4 | 1998 | Pioneer LDC, Inc. Japan |
| Sony PlayStation CD |  Service Price Edition: Love Game's - Wai Wai Tennis Model SLPS-01647 | 1998 | Tears Japan |
| Sony PlayStation CD | Sesame Street - Elmo's Letter Adventure Model SLUS-00621 | 1998 | NewKidCo International, Inc. |
| Sony PlayStation CD | Sesame Street - Elmo's Number Journey Model SLUS-00622 | 1998 | NewKidCo International, Inc. |
| Sony PlayStation CD | Shadow Gunner - The Robot Wars Model SLES-01359 | 1998 | UBI Soft Creteil, France 307211 |
| Sony PlayStation CD | Shadow Master Model SLES-00888 | 1998 | Psygnosis, Ltd. |
| Sony PlayStation CD | Shadow Master Model SLUS-00545 | 1998 | Psygnosis, Ltd. |
| Sony PlayStation CD | Shadow Tower Model SLPS-01420 | 1998 | From Soft. |
| Sony PlayStation CD | Shake Kids Model SLPS-01472 | 1998 | On DiMand Co., Ltd. Japan |
| Sony PlayStation CD | Shane Warne Cricket '99 Model SLES-01576 | 1998 | Codemasters Soft. Co., Ltd., The 015026 |
| Sony PlayStation CD | Shanghai - Mateki Buyuu Model SLPS-01552 | 1998 | SUNSOFT Kounan, Japan |
| Sony PlayStation CD | Shichisei Toushin Guyferd - Crown Kaimetsu Sakusen Model SLPS-01619 | 1998 | Capcom Co., Ltd. Japan |
| Sony PlayStation CD | Shin Nihon Pro Wrestling - Toukon Retsuden 3 Model SLPS-01314 | 1998 | Tomy |
| Sony PlayStation CD | Shin Nihon Pro Wrestling - Toukon Retsuden 3 Model SLPS-01366 | 1998 | Tomy |
| Sony PlayStation CD | Shin Sedai Robot Senki - Brave Saga Model SLPS-01755 | 1998 | Takara Co., Ltd. Japan |
| Sony PlayStation CD | Shin Sedai Robot Senki - Brave Saga Model SLPS-01756 | 1998 | Takara Co., Ltd. Japan |
| Sony PlayStation CD | Shin Seiki Evangelion - Eva to Yukai na Nakama-tachi Model SLPS-01485 | 1998 | Gainax Japan |
| Sony PlayStation CD | Shiritsu Justice Gakuen - Legion of Heroes Model SLPS-01240~1 | 1998 | Capcom Co., Ltd. Japan |
| Sony PlayStation CD | Shisenfuu Gekikara Mahjong Model SLPS-01648 | 1998 | C-lab Japan |
| Sony PlayStation CD | Shougi Saikyou 2 Model SLPM-86069 | 1998 | Magical Co., Ltd. Japan |
| Sony PlayStation CD | Shura no Mon Model SLPS-01202 | 1998 | Kodansha Japan |
| Sony PlayStation CD | Side Pocket 3 - 3D Polygon Billiard Game Model SLPS-01079 | 1998 | Data East Corp. Japan |
| Sony PlayStation CD | Silent Möbius - Case: Titanic Model SLPS-01618 | 1998 | Gainax Japan |
| Sony PlayStation CD | Silent Möbius - Genei no Datenshi Model SLPS-01803 | 1998 | Bandai Co., Ltd. Japan |
| Sony PlayStation CD | Silhouette Mirage - Reprogrammed Hope Model SLPS-01449 | 1998 | ESP Ent. Soft. Publishing |
| Sony PlayStation CD | Sim City 2000 Model SLPS-91098 | 1998 | Artdink Corp. Japan |
| Sony PlayStation CD | Simple 1500 Series Vol. 1: The Mahjong Model SLPS-01631 | 1998 | Culture Publishers |
| Sony PlayStation CD | Simple 1500 Series Vol. 2: The Shougi Model SLPS-01632 | 1998 | Culture Publishers |
| Sony PlayStation CD | Simple 1500 Series Vol. 3: The Gomoku Narabe Model SLPS-01633 | 1998 | Culture Publishers |
| Sony PlayStation CD | Simple 1500 Series Vol. 4: The Reversi Model SLPS-01634 | 1998 | Culture Publishers |
| Sony PlayStation CD | Simple 1500 Series Vol. 5: The Igo Model SLPS-01683 | 1998 | Culture Publishers |
| Sony PlayStation CD | Simple 1500 Series Vol. 6: The Hanafuda Model SLPS-01684 | 1998 | Culture Publishers |
| Sony PlayStation CD | Simple 1500 Series Vol. 7: The Card Model SLPS-01685 | 1998 | Culture Publishers |
| Sony PlayStation CD | Simple 1500 Series Vol. 8: The Solitaire Model SLPS-01686 | 1998 | Culture Publishers |
| Sony PlayStation CD | Simulation RPG Tsukuru Model SLPS-00876 | 1998 | ASCII Corp. Japan |
| Sony PlayStation CD | Ski Air Mix Model SLPS-01476 | 1998 | KID Kindle Imagine Develop |
| Sony PlayStation CD | Skullmonkeys Model SLES-01090 | 1998 | Electronic Arts CA, USA 14633 |
| Sony PlayStation CD | Skullmonkeys Model SLES-01091 | 1998 | Electronic Arts CA, USA 14633 |
