| TRS-80 cass. |  Micro-80 Pinball Machine | 1980 | Micro-80, Inc. |
| TRS-80 cass. | Microchess | 1980 | Rainbow Computing, Inc. |
| TRS-80 cass. | MiGs & Messerschmitts | 1980 | Wesely & Maker |
| TRS-80 cass. | Mind Warp | 1980 | Instant Soft., Inc. |
| TRS-80 cass. | Monty Plays Monopoly | 1980 | Ritam Corp. |
| TRS-80 cass. | Name That State Quiz | 1980 | Synergistic Solar, Inc. |
| TRS-80 cass. | Olympic Decathlon | 1980 | Microsoft |
| TRS-80 cass. | Pacifica | 1980 | Rainbow Computing, Inc. |
| TRS-80 cass. | Parsector V Parsector 8 | 1980 | Synergistic Solar, Inc. |
| TRS-80 cass. | Pot O'Gold I | 1980 | Rainbow Computing, Inc. |
| TRS-80 cass. | Pot O'Gold II | 1980 | Rainbow Computing, Inc. |
| TRS-80 cass. | Pursuit Games Model CS-3004 | 1980 | Creative Computing Soft. |
| TRS-80 cass. | Rainbow's Casino | 1980 | Rainbow Computing, Inc. |
| TRS-80 cass. | Slag Model 010-0018 | 1980 | Adventure International |
| TRS-80 cass. | Softside April | 1980 | SoftSide Publications, Inc. |
| TRS-80 cass. | Softside August CV | 1980 | SoftSide Publications, Inc. |
| TRS-80 cass. | Softside December CV | 1980 | SoftSide Publications, Inc. |
| TRS-80 cass. | Softside February | 1980 | SoftSide Publications, Inc. |
| TRS-80 cass. | Softside January | 1980 | SoftSide Publications, Inc. |
| TRS-80 cass. | Softside June | 1980 | SoftSide Publications, Inc. |
| TRS-80 cass. | Softside March | 1980 | SoftSide Publications, Inc. |
| TRS-80 cass. | Softside May | 1980 | SoftSide Publications, Inc. |
| TRS-80 cass. | Softside November CV | 1980 | SoftSide Publications, Inc. |
| TRS-80 cass. | Softside October CV | 1980 | SoftSide Publications, Inc. |
| TRS-80 cass. | Softside September CV | 1980 | SoftSide Publications, Inc. |
| TRS-80 cass. | Space Colony Model 010-0053 | 1980 | Adventure International |
| TRS-80 cass. | Space Games-3 Model CS-3002 | 1980 | Creative Computing Soft. |
| TRS-80 cass. | Space Warp Model 26-1912 | 1980 | Radio Shack Fort Worth, TX, USA |
| TRS-80 cass. | Spider Mountain Adventure | 1980 | Programmer's Guild, The |
| TRS-80 cass. | Star Trader Orion | 1980 | Automated Simulations, Inc. |
| TRS-80 cass. | Star Trek + Star Wars | 1980 | Rainbow Computing, Inc. |
| TRS-80 cass. | Star Trek 3.5 Model 010-0025 | 1980 | Adventure International |
| TRS-80 cass. | Star Trek III.5 | 1980 | Ramware |
| TRS-80 cass. | Strategy Games Model CS-3005 | 1980 | Creative Computing Soft. |
| TRS-80 cass. | Super Nova | 1980 | Big Five Soft. Van Nuys, CA, USA |
| TRS-80 cass. | T80-FS1 Flight Simulator | 1980 | SubLOGIC Corp. Champaign, IL, USA |
| TRS-80 cass. | The Count Model CS-3011 | 1980 | Creative Computing Soft. |
| TRS-80 cass. | The Great Race Model 011-0035 | 1980 | Adventure International |
| TRS-80 cass. | The Human Adventure | 1980 | Med Systems |
| TRS-80 cass. | The Mean Checker Machine Model 010-0040 | 1980 | Adventure International |
