| PC/MS-Windows CD |  Education Platinum Sw | 1994 | Limelight Media, Inc. Terre Haute, IN, USA |
| PC/MS-Windows CD | EF2000 Tactcom | 1996 | Ocean Soft., Ltd. 13156 |
| PC/MS-Windows CD | eGames Master's Edition 151 | 2002 | eGames, Inc Langhorne, PA, USA |
| PC/MS-Windows CD | Eggerland Episode 0 - Quest of Lala | 1996 | HAL Laboratory, Inc. Japan |
| PC/MS-Windows CD | Egypt 1156 B.C. - Tomb of the Pharaoh | 1998 | Cryo Interactive Ent. |
| PC/MS-Windows CD | Egypt II - The Heliopolis Prophecy | 2000 | DreamCatcher Interactive |
| PC/MS-Windows CD | Eighteen | 2004 | Inter Heart Japan |
| PC/MS-Windows CD | Eigou-Kaiki | 2004 | DO Corp. Japan |
| PC/MS-Windows CD | Eiyuu Densetsu V - Umi no Oriuta | 199? | Falcom Nihon Falcom Corp. Japan |
| PC/MS-Windows CD | Electric Device Marian | 1995 | Janis Computer Soft., Inc. Japan |
| PC/MS-Windows CD | Elements of Destruction | 2008 | ValuSoft |
| PC/MS-Windows CD | Elements Of War | 2011 | Kalypso Media GmbH |
| PC/MS-Windows CD | Elf All Star Datsui-Jan | 2000 | Elf Japan |
| PC/MS-Windows CD | Elf All Star Datsui-Jan 2 | 2001 | Elf Japan |
| PC/MS-Windows CD | Elf Hime Nina - Jutai Juurin | 2008 | Black Lilith |
| PC/MS-Windows CD | Eliminator | 1999 | Psygnosis, Ltd. |
| PC/MS-Windows CD | Elminage Gothic | 2014 | Ghostlight, Ltd. |
| PC/MS-Windows CD | Elven Legacy | 2009 | Paradox Interactive |
| PC/MS-Windows CD | Emergency - Fighters for Life | 1998 | TopWare Interactive AG |
| PC/MS-Windows CD | Emergency 2 - The Ultimate Fight for Life | 2003 | Take-Two Interactive |
| PC/MS-Windows CD | Emergency 2012 | 2010 | Deep Silver, Inc. |
| PC/MS-Windows CD | Emergency 2013 | 2012 | Deep Silver, Inc. |
| PC/MS-Windows CD | Emergency 2014 | 2013 | Deep Silver, Inc. |
| PC/MS-Windows CD | Emergency 3 | 2005 | Strategy First |
| PC/MS-Windows CD | Emergency Fire Response | 2003 | DreamCatcher Interactive |
| PC/MS-Windows CD | Emergency Police | 2000 | KOCH Media Deutschland GmbH |
| PC/MS-Windows CD | Emergency Room 2 | 1999 | Legacy Interactive |
| PC/MS-Windows CD | EMIT Value Set Model KN10991030 | 199? | KOEI Co., Ltd. Japan |
| PC/MS-Windows CD | EMIT Vol. 1 - Toki no Maigo Model KN10601040 | 1994 | KOEI Co., Ltd. Japan |
| PC/MS-Windows CD | EMIT Vol. 3 - Watashi ni Sayonara o Model KN10741050 | 1995 | KOEI Co., Ltd. Japan |
| PC/MS-Windows CD | Emperor - Battle for Dune | 2001 | Electronic Arts CA, USA 14633 |
| PC/MS-Windows CD | Emperor - Rise of the Middle Kingdom | 2002 | Sierra Ent., Inc. USA |
| PC/MS-Windows CD | Empire - Total War | 2009 | SEGA Corp. |
| PC/MS-Windows CD | Empire Earth | 2001 | Vivendi Universal Games, Inc. |
| PC/MS-Windows CD | Empire Earth - The Art of Conquest | 2002 | Sierra Ent., Inc. USA |
| PC/MS-Windows CD | Empire Earth II | 2005 | Vivendi Universal Games, Inc. |
| PC/MS-Windows CD | Empire Earth III | 2007 | Vivendi Universal Games, Inc. |
| PC/MS-Windows CD | Empire of the Ants | 2000 | Microïds |
| PC/MS-Windows CD | Empires - Dawn of the Modern World | 2003 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| PC/MS-Windows CD | Enclave | 2002 | Vivendi Universal Games, Inc. |
