| Pachinko |  Segawa Eiko de Gozaimasu Model FX | 2004 | Maruhon Japan |
| Pachinko | Segawa Eiko de Gozaimasu Model MX | 2004 | Maruhon Japan |
| Medal game (video) | Sekai Kaseki Hakken | 2004 | NAMCO, Ltd. Japan |
| MSX cart. | Seleniak Hb | 2004 | Guzuta |
| Sony PlayStation 2 disc | Sengoku Ace & Sengoku Blade Psikyo Shooting Collection Vol.2 Model SLPM-62563 | 2004 | Taito Corp. Japan |
| PC/MS-Windows CD | Sentinel - Descendants in Time | 2004 | DreamCatcher Interactive |
| Nintendo GBA cart. | Sentouin Yamada Hajime Model AGB-BSYJ-JPN | 2004 | Kids Station |
| Medal game (video) | Sepian | 2004 | Unknown Korea |
| Nintendo GameCube disc | Serious Sam - Next Encounter Model DOL-G3BE-USA | 2004 | Global Star Soft. |
| Nintendo GBA cart. | Serious Sam Advance Model AGB-AENE-USA | 2004 | Global Star Soft. |
| Nintendo GBA cart. | Serious Sam Advance Model AGB-AENP | 2004 | Global Star Soft. |
| Slot Machine | Sev-Vin the Clowns | 2004 | IGT International Game Technologies Reno, NV, USA |
| Medal game (video) | Seven Fever | 2004 | Unknown Korea |
| Medal game (video) | Seven Steal Alpha | 2004 | ITec Korea |
| Medal game (video) | Seven Steal Beta | 2004 | ITec Korea |
| Slot Machine | Seven Streak | 2004 | WMS Gaming, Inc. Chicago, IL, USA |
| Slot Machine | Seven Strike | 2004 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Seven Times Pay Party Party Time! | 2004 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Sevenman Bonus | 2004 | Dragon Co., Ltd. |
| PC/MS-Windows CD | Sexy Beach 2 - Chiku Chiku beach | 2004 | Illusion Japan |
| Sony PlayStation 2 disc |  Shadow of Rome demo Model SLUS-29139 | 2004 | Capcom Ent., Inc. USA 13388 |
| Sony PlayStation 2 disc | Shadow of Rome Taikenban Model SLPM-61109 | 2004 | Capcom Co., Ltd. Japan |
| PC/MS-Windows CD | Shadow Ops - Red Mercury | 2004 | Atari Interactive, Inc. |
| Microsoft XBOX disc | Shadow Ops - Red Mercury | 2004 | Unknown |
| Slot Machine | Shake Dem Bones | 2004 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Shake Your Booty | 2004 | IGT International Game Technologies Reno, NV, USA |
| Slot Machine | Shanghai Surprise | 2004 | IGT International Game Technologies Reno, NV, USA |
| Nintendo GBA cart. | Shark Story | 2004 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo GBA cart. | Shark Tale Model AGB-B9TJ-JPN | 2004 | Taito Corp. Japan |
| Nintendo GBA cart. | Shark Tale Model AGB-BSUE-USA | 2004 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo GBA cart. | Shark Tale Model AGB-BSUP | 2004 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| PC/MS-Windows CD | Shellshock - Nam '67 | 2004 | Eidos Interactive |
| Microsoft XBOX disc | Shellshock - Nam '67 | 2004 | Unknown |
| PC/MS-Windows CD | Sherlock Holmes - Secret of the Silver Earring | 2004 | Ubisoft Ent. Montreuil sous Bois, France |
| Nintendo GBA cart. | Shikakui Atama o Maruku Suru. Advance - Kanji, Keisan Model AGB-B4KJ-JPN | 2004 | Rocket Co. Japan |
| Nintendo GBA cart. | Shikakui Atama o Maruku Suru. Advance - Kokugo, Sansuu, Shakai, Rika Model AGB-B4RJ-JPN | 2004 | Rocket Co. Japan |
| PC/MS-Windows CD | Shikigami no Shiro II | 2004 | Media Quest Japan |
| PC/MS-Windows CD | Shimai 2 | 2004 | 13cm Japan |
| Pachislot | Shimanchu | 2004 | Eipex Tokyo, Japan |
| Nintendo GBA cart. | Shin Megami Tensei Devil Children - Messiah Riser Model AGB-BDLJ-JPN | 2004 | Atlus Co., Ltd. Japan |
