| Nintendo GBA cart. |  Shikakui Atama o Maruku Suru. Advance - Kokugo, Sansuu, Shakai, Rika Model AGB-B4RJ-JPN | 2004 | Rocket Co. Japan |
| PC/MS-Windows CD | Shikigami no Shiro II | 2004 | Media Quest Japan |
| PC/MS-Windows CD | Shimai 2 | 2004 | 13cm Japan |
| Pachislot | Shimanchu | 2004 | Eipex Tokyo, Japan |
| Nintendo GBA cart. | Shin Megami Tensei Devil Children - Messiah Riser Model AGB-BDLJ-JPN | 2004 | Atlus Co., Ltd. Japan |
| Pachinko | Shin Meiga | 2004 | Heiwa Japan |
| Sony PSP UMD | Shin Sangoku Musou | 2004 | KOEI Co., Ltd. Japan |
| Sony PlayStation 2 disc | Shin Sangoku Musou 3 - Empires Model SLPM-65561/SLPM-62498 | 2004 | KOEI Co., Ltd. Japan |
| Sony PlayStation 2 disc | Shin Sangoku Musou 3 - Empires Model SLPM-65564/SLPM-62498 | 2004 | KOEI Co., Ltd. Japan |
| Sony PlayStation 2 disc | Shin Sangoku Musou 3 - Empires Model SLPM-65565 | 2004 | KOEI Co., Ltd. Japan |
| Pachinko | Shin Umimonogatari Special | 2004 | Sanyo Japan |
| Nintendo GBA cart. | Shingata Medarot - Kabuto Version Model AGB-BKVJ-JPN | 2004 | Imagineer Co., Ltd. Japan |
| Nintendo GBA cart. | Shingata Medarot - Kuwagata Version Model AGB-BKUJ-JPN | 2004 | Imagineer Co., Ltd. Japan |
| Slot Machine | Shining Crystal Model WMH-209SC | 2004 | Paokai Electronic Enterprise Co., Ltd. Taiwan |
| Nintendo GBA cart. | Shining Force - Kuroki Ryuu no Fukkatsu Model AGB-AF5J-JPN | 2004 | SEGA Corp. |
| Nintendo GBA cart. |  Shining Force - Resurrection of the Dark Dragon Model AGB-AF5E-USA | 2004 | Atlus USA, Inc. CA, USA |
| Nintendo GBA cart. | Shining Force - Resurrection of the Dark Dragon Model AGB-AF5P | 2004 | T-HQ, Inc. Toy HeadQuarters |
| Nintendo GBA cart. | Shining Soul II Model AGB-AU2E-USA | 2004 | Atlus USA, Inc. CA, USA |
| Nintendo GBA cart. | Shining Soul II Model AGB-AU2P | 2004 | T-HQ, Inc. Toy HeadQuarters |
| PC/MS-Windows CD | ShinSeiki Evangerion - Ikari Shinji Ikusei Keikaku | 2004 | Gainax Japan |
| Slot Machine | Shiny Penny | 2004 | IGT International Game Technologies Reno, NV, USA |
| Nintendo GBA cart. | Shiren Monsters Netsal Model AGB-ANVJ-JPN | 2004 | Chun Soft |
| Nintendo GBA cart. | Shonen Jump's Shaman King - Master of Spirits Model AGB-BSOE-USA | 2004 | Konami Corp. Japan |
| Nintendo GBA cart. | Shonen Jump's Yu-Gi-Oh Destiny Board Traveler Model AGB-BYDE-USA | 2004 | Konami Corp. Japan |
| Nintendo GBA cart. | Shonen Jump's Yu-Gi-Oh Reshef of Destruction Model AGB-AY8E-USA | 2004 | Konami Corp. Japan |
| Nintendo GBA cart. | Shonen Jump's Yu-Gi-Oh! World Championship Tournament 2004 Model AGB-BYWE-USA | 2004 | Konami Corp. Japan |
| Redemption mechanical game | Shoot it Up | 2004 | Andamiro Co., Ltd. |
| Slot Machine | Show Boat | 2004 | WMS Gaming, Inc. Chicago, IL, USA |
| Sony PlayStation 2 disc | Showdown - Legends of Wrestling Model SLES-52579 | 2004 | Acclaim Ent., Inc. Glen Cove, NY, USA |
| Nintendo GBA cart. | Shrek 2 - Beg for Mercy Model AGB-BSIE-USA | 2004 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo GBA cart. | Shrek 2 - Beg for Mercy Model AGB-BSIP | 2004 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo GBA cart. | Shrek 2 Model AGB-BSEX-EUR | 2004 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo GBA cart. | Shrek 2 Model AGB-BSSE-USA | 2004 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo GBA cart. | Shrek 2 Model AGB-BSSP | 2004 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo GameCube disc | Shrek 2 Model DOL-G3RD-NOE | 2004 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo GameCube disc | Shrek 2 Model DOL-G3RE-USA | 2004 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Sony PlayStation 2 disc | Shrek 2 Model SLES-52457 | 2004 | Activision Publishing, Inc. Los Angeles, CA, USA 47875 |
| Nintendo Famicom cart. | Shui Hu Shen Shou Model ES-1087 | 2004 | Waixing Computer & Technology Co., Ltd. China |
| Nintendo Famicom cart. | Shui Hu Shen Shou Model NJ019 | 2004 | Shenzhen Nanjing Technology Co., Ltd. China |
| Amstrad CPC 464 disk | Shyntow - Le chemin de l'esprit Hb | 2004 | Unknown |
