| Sinclair ZX Spectrum pack. |  Escape From Singe's Castle Model 147 | 1991 | EDOS Electronic Distribution of Software |
| Arcade Video game |  Escape Kids | 1991 | Konami Industry Co., Ltd. Japan |
| MSX 2 disk | Estland Monogatari - Estland Campaing | 1991 | Medo Japan |
| Sega Game Gear cart. | Eternal Legend - Eien no Densetsu Model G-3402 | 1991 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sinclair ZX Spectrum cass. | Euro Boss | 1991 | Challenge Soft. |
| Amstrad CPC cass. | Euro Boss | 1991 | Challenge Soft. |
| IBM PC 3.5in. disk | Euro-Stad | 1991 | HVB Soft. |
| NEC PC-8801 Series disk | Europa Sensen Model KN10221010 | 1991 | KOEI Co., Ltd. Japan |
| Commodore C64 cass. | European Football Champ | 1991 | Domark Group, Ltd. |
| Sinclair ZX Spectrum cass. | European Superleague | 1991 | CDS Soft., Ltd. |
| Amstrad CPC 464 disk |  European Superleague | 1991 | Proein Soft Line Spain |
| Sinclair ZX Spectrum+3 disk | European Superleague | 1991 | CDS Soft., Ltd. |
| Amstrad CPC 464 disk | European Superleague | 1991 | CDS Soft., Ltd. |
| Sinclair ZX Spectrum+3 disk | Even Yet Another Big Disk | 1991 | Zenobi Soft. |
| Amstrad CPC pack. | Everyone's A Wally - Meet The Gang | 1991 | EDOS Electronic Distribution of Software |
| Pool Table | Excalibur | 1991 | Dynamo Corp. Grand Prairie, TX, USA |
| Commodore Amiga 500 disk | Exile | 1991 | ASL Audiogenic Soft., Ltd. |
| Atari ST disk | Exile | 1991 | ASL Audiogenic Soft., Ltd. |
| Commodore C64 disk | Exile | 1991 | ASL Audiogenic Soft., Ltd. |
| Commodore C64 cass. | Exile | 1991 | ASL Audiogenic Soft., Ltd. |
| NEC PC-Engine CD | Exile - Toki no Hasama he Model TJCD1014 | 1991 | Telenet Japan |
| Sega Mega Drive cart. | Exile - Toki no Hazama he Model T-49093 | 1991 | Riot Japan |
| Sega Genesis cart. | Exile Model 49186 | 1991 | Renovation Products USA |
| Nintendo NES cart. | Exodus - Journey to the Promised Land | 1991 | Wisdom Tree, Inc. CA, USA |
| Amstrad CPC pack. | Exolon Model 364 | 1991 | EDOS Electronic Distribution of Software |
| Sharp X68000 Series 5.25in. disk | eXOn | 1991 | Softec Japan |
| NEC PC-9801 Series 5.25in. disk | eXOn | 1991 | Softec Japan |
| NEC PC-9801 Series 5.25in. disk |  eXOn Demo | 1991 | Softec Japan |
| V.R. game | Exorex | 1991 | Virtuality, Ltd. Virtuality Group |
| Commodore C64 disk | Exploding Atoms | 1991 | Markt & Technik |
| Amstrad CPC pack. | Exploding Wall | 1991 | EDOS Electronic Distribution of Software |
| Acorn BBC Micro B disk | Explorer | 1991 | DragonSoft |
| Sinclair ZX Spectrum cass. | Exterminator | 1991 | ASL Audiogenic Soft., Ltd. |
| Amstrad CPC 464 disk | Exterminator | 1991 | System 4 de Espana, S.A. Spain |
| Amstrad CPC cass. | Exterminator Model 4 SHX-375 | 1991 | System 4 de Espana, S.A. Spain |
| Amstrad CPC cass. | Exterminator Model ASL60AM | 1991 | ASL Audiogenic Soft., Ltd. |
| Nintendo Game Boy Cart. | Extra Bases! Model DMG-FS-USA | 1991 | Bandai America, Inc. 45557 |
| NEC PC-8801 Series disk | Extra Disk vol. 1 | 1991 | Unknown Japan |
| Slot Machine | Extrabelle Regal model | 1991 | Royal Bell, Ltd. |
| Sinclair ZX Spectrum cass. | Extreme | 1991 | Digital Integration |
