| Sinclair ZX Spectrum+3 disk |  Escape from the Planet of the Robot Monsters | 1990 | Erbe Soft. Spain |
| Atari ST disk |  Escape from the Planet of the Robot Monsters | 1990 | Domark Group, Ltd. |
| Commodore C64 cass. | Escape from the Planet of the Robot Monsters | 1990 | Domark Group, Ltd. |
| Sinclair ZX Spectrum cass. | Escape from the Planet of the Robot Monsters Model 485-5 | 1990 | Domark Group, Ltd. |
| Amstrad CPC cass. | Escape from the Planet of the Robot Monsters Model AM 600 | 1990 | Erbe Soft. Spain |
| Atari ST disk | Espacial | 1990 | Aventuras AD, S.A. Spain |
| Commodore C64 cass. | ESWAT | 1990 | US Gold, Ltd. Birmingham, England 13442 |
| Sega Mega Drive cart. | ESWAT - City Under Siege | 1990 | SEGA Enterprises, Ltd. Tokyo, Japan |
| Sega Genesis cart. | ESWAT - City Under Siege Model 1110 | 1990 | SEGA of America, Inc. San Francisco, CA, USA |
| Amstrad CPC 464 disk | Etrange Castel Hb | 1990 | Fanatic |
| Arcade Video game |  Eunos Roadster Driving Simulator | 1990 | NAMCO, Ltd. Japan |
| Commodore Amiga 500 disk |  European Soccer Challenge | 1990 | Smash 16 |
| Sinclair ZX Spectrum cass. | European Soccer Challenge | 1990 | Players Soft. |
| Amstrad CPC cass. | European Soccer Challenge | 1990 | Players Soft. |
| Commodore C64 cass. | European Soccer Challenge | 1990 | Players Soft. |
| Commodore Amiga 500 disk | European Superleague | 1990 | CDS Soft., Ltd. |
| Arcade Video game | Every Second Counts | 1990 | Bell-Fruit Mfg. Co., Ltd. B.F.M. UK |
| Arcade Video game | Evil Stone | 1990 | Spacy Industrial, Ltd. |
| Fujitsu FM Towns CD | Excellent 10 Model HMB-201 | 1990 | Amorphous Japan |
| Sinclair ZX Spectrum cass. | Excessus | 1990 | Wazertown Works Spain |
| MSX type-in | Excite Derby | 1990 | Dempa Shinbunsha Japan |
| Nintendo Famicom BASIC type-in | Exciting Arithmetic | 1990 | Dempa Shinbunsha Japan |
| National JR-200 type-in | Exclude II | 1990 | Dempa Shinbunsha Japan |
| Sharp X1 5.25in. disk | Exodus - Ultima III Model M88J5555 | 1990 | Pony Canyon, Inc. Japan |
| Sinclair ZX Spectrum cass. | Expedice | 1990 | Proxima Soft. Czech Republic |
| Nintendo NES cart. | Exploding Fist | 1990 | Tradewest, Inc. Corsicana, TX, USA |
| Amstrad CPC cass. | Exploding Wall | 1990 | Byte Back 018854 |
| Commodore C64 cass. | Exploding Wall | 1990 | MC Lothlorien |
| Amstrad CPC type-in | Explor | 1990 | Laser Press SARL Saint-Mandé, France |
| Commodore Amiga 500 disk | Explora III - Sous le signe du Serpent | 1990 | 16 32 Diffusion France |
| Atari ST disk | Explora III - Sous le Signe du Serpent | 1990 | Infomedia France |
| Commodore Amiga 500 disk | Extase | 1990 | Virgin Interactive Ent., Ltd. UK 013715 |
| Atari ST disk | Extase | 1990 | Virgin Games, Ltd. UK 013715 |
| Sharp X68000 Series 5.25in. disk | Exterlien 18 | 1990 | DO Corp. Japan |
| NEC PC-9801 Series 5.25in. disk | Exterlien 18 | 1990 | DO Corp. Japan |
| NEC PC-8801 Series disk | Exterlien 18 | 1990 | DO Corp. Japan |
| MSX 2 disk | Exterlien 18 | 1990 | DO Corp. Japan |
| Commodore Amiga 500 disk | Exterminator | 1990 | ASL Audiogenic Soft., Ltd. |
| Atari ST disk | Exterminator | 1990 | ASL Audiogenic Soft., Ltd. |
| Commodore C64 cass. | Exterminator | 1990 | ASL Audiogenic Soft., Ltd. |
