| Nintendo Game Boy Cart. |  Dragon Slayer I Model DMG-DSA | 1990 | Epoch Co., Ltd. Tokyo, Japan |
| Nintendo NES cart. |  Dragon Spirit - The New Legend Model NES-P4-USA | 1990 | Bandai America, Inc. 45557 |
| Nintendo Game Boy Cart. | Dragon Tail Model DMG-DRA | 1990 | I'Max Japan |
| Nintendo Famicom cart. | Dragon Unit Model ATH-ZX | 1990 | Athena Co., Ltd. Japan |
| Nintendo NES cart. | Dragon Warrior II Model NES-D2-USA | 1990 | Enix of America |
| Commodore Amiga 500 disk | Dragon Wars | 1990 | Interplay |
| Apple IIGS disk | Dragon Wars | 1990 | Interplay |
| NEC PC-9801 Series 5.25in. disk | Dragon Wars Model SCF03NEF54 | 1990 | Starcraft, Inc. Japan |
| NEC TurboGrafx-16 cart. | Dragon's Curse Model TGX020039 | 1990 | NEC Home Electronics, Ltd. |
| IBM PC/AT DOS 3.5in. disk |  Dragon's Lair | 1990 | Merit Soft. |
| Commodore Amiga 500 disk | Dragon's Lair - Escape from Singe's Castle | 1990 | Visionary |
| Atari ST disk | Dragon's Lair - Escape from Singe's Castle | 1990 | ReadySoft, Inc. Canada |
| Nintendo NES cart. | Dragon's Lair Model NES-L9-USA | 1990 | CSG Imagesoft |
| Commodore Amiga 500 disk | Dragonflight | 1990 | Grandslam Ent., Ltd. |
| Atari ST disk | Dragons Breath | 1990 | Palace Soft. 013518 |
| Commodore Amiga 500 disk | Drakkhen | 1990 | Infogrames Interactive, Inc. 329720 |
| Commodore Amiga 500 disk | Drakkhen | 1990 | Draconian |
| IBM PC 5.25in. disk | Drakkhen | 1990 | Infogrames Interactive, Inc. 329720 |
| Fujitsu FM Towns CD | Drakkhen Model TSC130 | 1990 | Fujitsu, Ltd. Japan |
| Atari 400/800 cass. | Dreadnought | 1990 | Byte Back 018854 |
| NEC PC-6001mkII type-in | Dream Land - Obake no Undoukai | 1990 | Dempa Shinbunsha Japan |
| NEC PC-8801 Series disk | Dreamy Alien Girls | 1990 | Great Japan |
| Amstrad CPC type-in | Drehdriss | 1990 | DMV Daten und Medien Verlag Eschwege, Germany |
| IBM PC DOS pack. | DressMeUp | 1990 | ShareGames |
| Commodore Amiga 500 disk | Drivin' Force | 1990 | Digital Magic |
| Sharp X68000 type-in | Drop Block | 1990 | Dempa Shinbunsha Japan |
| NEC TurboGrafx-16 cart. | Drop Off Model TGX020042 | 1990 | NEC Home Electronics, Ltd. |
| NEC PC-Engine HuCARD | Drop Rock Hora Hora Model DE90005 | 1990 | Data East Corp. Japan |
| Acorn Archimedes disk | Drop Ship | 1990 | Fourth Dimension, The |
| MSX type-in | Dropper | 1990 | Dempa Shinbunsha Japan |
| Nintendo Game Boy Cart. | Druaga no Tou Model DMG-ADA | 1990 | Angel Studios |
| Nintendo NES cart. | Duck Maze Model HES-DM | 1990 | HES Home Ent. Suppliers Sydney, Australia |
| Nintendo NES cart. | Dudes with Attitude | 1990 | American Video Ent., Inc. Burlingame, CA, USA |
| NEC PC-9801 Series 5.25in. disk | Duel | 1990 | KSK Kure Soft. Koubou Japan |
| NEC PC-8801 Series disk | Duel - Kawanakajima Scenario | 1990 | KSK Kure Soft. Koubou Japan |
| IBM PC DOS pack. | Dueling Dragons | 1990 | ShareGames |
| NEC PC-8801 Series disk | Duet | 1990 | Unknown Japan |
| Hartung Game Master cart. | Dungeon Adventure | 1990 | Hartung |
| NEC PC-9801 Series 5.25in. disk | Dungeon Buster 18 | 1990 | Great Japan |
| NEC PC-8801 Series disk | Dungeon Buster | 1990 | Great Japan |
